2023
A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial
Katamba A, Gupta A, Turimumahoro P, Ochom E, Ggita J, Nakasendwa S, Nanziri L, Musinguzi J, Hennein R, Sekadde M, Hanrahan C, Byaruhanga R, Yoeli E, Turyahabwe S, Cattamanchi A, Dowdy D, Haberer J, Armstrong-Hough M, Kiwanuka N, Davis J. A user-centred implementation strategy for tuberculosis contact investigation in Uganda: protocol for a stepped-wedge, cluster-randomised trial. BMC Public Health 2023, 23: 1568. PMID: 37592314, PMCID: PMC10436440, DOI: 10.1186/s12889-023-16510-0.Peer-Reviewed Original ResearchConceptsContact investigationClinical effectiveness outcomesPrimary implementation outcomeTB contact investigationTB preventative therapyTB treatment initiationTimely TB diagnosisTrial registrationThe trialTuberculosis contact investigationCluster-randomised trialHigh-burden settingsImplementation-effectiveness trialEvidence-based interventionsUganda National CouncilWorld Health OrganizationProportion of contactsTB evaluationPeer-reviewed journalsMiddle-income countriesTreatment initiationTB diagnosisPreventative therapyUndiagnosed personsInfectious deathSputum samples
2022
Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial
Armstrong-Hough M, Ggita J, Gupta AJ, Shelby T, Nangendo J, Ayen DO, Davis JL, Katamba A. Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial. BMJ Open 2022, 12: e061508. PMID: 35613785, PMCID: PMC9134160, DOI: 10.1136/bmjopen-2022-061508.Peer-Reviewed Original ResearchConceptsCommunity health workersHIV testingHIV test uptakeHIV status awarenessHome HIV testingHousehold contactsContact investigationTB stigmaTest uptakeHIV stigmaPublic Health Institutional Review BoardHealth Institutional Review BoardTB contact investigationTuberculosis contact investigationCluster-randomised trialHousehold tuberculosis contact investigationPublic health facilitiesVerbal informed consentHuman Investigation CommitteeMakerere University SchoolInstitutional review boardUganda National CouncilProportion of contactsHome HIVStatus awarenessCost-effectiveness analysis of human-centred design for global health interventions: a quantitative framework
Liu C, Lee J, Gupta A, Tucker A, Larkin C, Turimumahoro P, Katamba A, Davis J, Dowdy D. Cost-effectiveness analysis of human-centred design for global health interventions: a quantitative framework. BMJ Global Health 2022, 7: e007912. PMID: 35346954, PMCID: PMC8961136, DOI: 10.1136/bmjgh-2021-007912.Peer-Reviewed Original ResearchConceptsCost-effectiveness analysisLong-term costsUp-front costsQuantitative frameworkCost scenariosIntervention costsLarge initial costGlobal health interventionsHealth interventionsCostContact investigationInitial costHealth benefitsTB contact investigationTuberculosis contact investigationPayWillingnessHealth systemFrameworkNumber of clientsDALYsBenefitsUgandaInterventionGlobal health
2021
A Cost Analysis of Implementing Mobile-Health Facilitated Tuberculosis Contact Investigation in a Low Income Setting
Turimumahoro P, Tucker A, Meyer A, Tampi R, Babirye D, Ochom E, Ggita J, Ayakaka I, Hojoon S, Katamba A, David D, Davis J. A Cost Analysis of Implementing Mobile-Health Facilitated Tuberculosis Contact Investigation in a Low Income Setting. 2021, a1722-a1722. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1722.Peer-Reviewed Original ResearchTuberculosis contact investigationLow-income settingsContact investigationIncome settingsCost analysisIdentifying the Functional Components of a Community of Practice to Improve Tuberculosis Contact Investigation in Uganda
Hennein R, Ggita J, Turimumahoro P, Ochom E, Meyer A, Armstrong-Hough M, Katamba A, Davis J. Identifying the Functional Components of a Community of Practice to Improve Tuberculosis Contact Investigation in Uganda. 2021, a3925-a3925. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3925.Peer-Reviewed Original ResearchTuberculosis contact investigationContact investigationEvaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study.
Diaz G, Victoria AM, Meyer AJ, Niño Y, Luna L, Ferro BE, Davis J. Evaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study. American Journal Of Tropical Medicine And Hygiene 2021, 104: 1309-1316. PMID: 33617470, PMCID: PMC8045602, DOI: 10.4269/ajtmh.20-0809.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyTuberculosis contact investigationContact investigationTB patientsHousehold visitsTB evaluationClinic visitsCohort studyEarly TB diagnosisIndex TB patientsTB contact investigationActive TB patientsTherapy initiationPreventive therapyTB diagnosisSymptomatic contactsMultivariable modelClinic referralsIndex patientsPatientsContact tracingVisitsCumulative probabilityLittle dataReferral
2019
Home-based tuberculosis contact investigation in Uganda: a household randomised trial
Davis JL, Turimumahoro P, Meyer AJ, Ayakaka I, Ochom E, Ggita J, Mark D, Babirye D, Okello DA, Mugabe F, Fair E, Vittinghoff E, Armstrong-Hough M, Dowdy D, Cattamanchi A, Haberer JE, Katamba A. Home-based tuberculosis contact investigation in Uganda: a household randomised trial. ERJ Open Research 2019, 5: 00112-2019. PMID: 31367636, PMCID: PMC6661318, DOI: 10.1183/23120541.00112-2019.Peer-Reviewed Original ResearchCommunity health workersTB contact investigationTuberculosis contact investigationContact investigationTB evaluationIndex patientsWorld Health OrganizationIntervention armHousehold tuberculosis contact investigationCare armHousehold contactsPulmonary TBSputum testingCare contactsHIV diagnosisSecondary outcomesHIV testingPrimary outcomeSymptomatic contactsHealth workersMicrobiologic testingHome evaluationIntervention componentsSputumPatients
2018
Text Messages Sent to Household Tuberculosis Contacts in Kampala, Uganda: Process Evaluation
Meyer AJ, Babirye D, Armstrong-Hough M, Mark D, Ayakaka I, Katamba A, Haberer JE, Davis JL. Text Messages Sent to Household Tuberculosis Contacts in Kampala, Uganda: Process Evaluation. JMIR MHealth And UHealth 2018, 6: e10239. PMID: 30459147, PMCID: PMC6280036, DOI: 10.2196/10239.Peer-Reviewed Original ResearchTuberculosis contact investigationHousehold tuberculosis contactHousehold contactsTuberculosis contactsContact investigationProcess evaluationText Messaging InterventionHousehold tuberculosis contact investigationText message interventionDetailed process evaluationText message deliveryText messagesIntervention armIndex patientsMessage interventionHealth outcomesSeparate daysYoung womenInconsistent effectivenessYoung adultsTelephone surveyYoung menInterventionText messagingDemographic differences
2017
Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study
Armstrong-Hough M, Turimumahoro P, Meyer AJ, Ochom E, Babirye D, Ayakaka I, Mark D, Ggita J, Cattamanchi A, Dowdy D, Mugabe F, Fair E, Haberer JE, Katamba A, Davis JL. Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study. PLOS ONE 2017, 12: e0187145. PMID: 29108007, PMCID: PMC5673209, DOI: 10.1371/journal.pone.0187145.Peer-Reviewed Original ResearchConceptsHousehold contact investigationNational TB ProgrammeContact investigationTB evaluationActive TBHealth workersPatient householdsMulti-center observational studyIndex TB patientsTB contact investigationLay health workersTuberculosis contact investigationMulti-center studyRoutine public health settingPublic health settingsTB patientsTB programsEligible contactsTuberculosis unitProgrammatic settingsRisk factorsIndex householdsIndex patientsObservational studyRisk contactsIdentifying barriers to and facilitators of tuberculosis contact investigation in Kampala, Uganda: a behavioral approach
Ayakaka I, Ackerman S, Ggita JM, Kajubi P, Dowdy D, Haberer JE, Fair E, Hopewell P, Handley MA, Cattamanchi A, Katamba A, Davis JL. Identifying barriers to and facilitators of tuberculosis contact investigation in Kampala, Uganda: a behavioral approach. Implementation Science 2017, 12: 33. PMID: 28274245, PMCID: PMC5343292, DOI: 10.1186/s13012-017-0561-4.Peer-Reviewed Original ResearchConceptsLay health workersTB contact investigationTuberculosis contact investigationContact investigationTB patientsHousehold contactsBackgroundThe World Health OrganizationIndex TB patientsHigh-burden countriesHousehold tuberculosis contact investigationHealth center staffHealth care workersWorld Health OrganizationFocus group discussionsScreening visitCross-sectional qualitative dataRelevant intervention functionsIndex patientsHealth workersRisk contactsPatientsTargeted interventionsClinicHealth OrganizationConclusionsThe use