2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfection
2007
Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections
Gupta K, MacIntyre A, Vanasse G, Dembry LM. Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections. Journal Of Clinical Microbiology 2007, 45: 3930-3934. PMID: 17942648, PMCID: PMC2168566, DOI: 10.1128/jcm.01510-07.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBeta-LactamsChildChild, PreschoolCommunity-Acquired InfectionsDrug PrescriptionsFemaleHealth Services ResearchHumansInfantInfant, NewbornMaleMethicillin ResistanceMiddle AgedPrevalenceStaphylococcal InfectionsStaphylococcus aureusUnited StatesConceptsCA-MRSA soft tissue infectionsSoft tissue infectionsInitial empirical therapyCA-MRSA isolatesEmpirical therapyAntimicrobial therapyCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolatesStaphylococcal chromosomal cassette mec type IVS. aureus soft tissue infectionsResistant Staphylococcus aureus infectionsMethicillin-Resistant Staphylococcus aureus IsolatesInactive antimicrobial therapyRate of prescribingCA-MRSA infectionsInitial antimicrobial therapyMajority of patientsMedical record reviewSubset of patientsCommunity-Associated MethicillinStaphylococcus aureus infectionPanton-Valentine leukocidinStaphylococcus aureus isolatesBeta-lactam antibioticsDiscordant therapyRate of use
2000
Molecular Typing Demonstrating Transmission of Gram-Negative Rods in a Neonatal Intensive Care Unit in the Absence of a Recognized Epidemic
Almuneef M, Baltimore R, Farrel P, Reagan-Cirincione P, Dembry L. Molecular Typing Demonstrating Transmission of Gram-Negative Rods in a Neonatal Intensive Care Unit in the Absence of a Recognized Epidemic. Clinical Infectious Diseases 2000, 32: 220-227. PMID: 11170911, DOI: 10.1086/318477.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Typing TechniquesCross InfectionDNA, BacterialDrug Resistance, MicrobialElectrophoresisFecesFemaleGenotypeGentamicinsGram-Negative Aerobic Rods and CocciGram-Negative Bacterial InfectionsHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMicrobial Sensitivity TestsConceptsNeonatal intensive care unitIntensive care unitShared strainsCare unitMolecular typing techniquesRectal swab culturesColonization of infantsGentamicin-resistant strainsWeeks of ageTyping techniquesAntibiotic treatmentAntibiotic useSwab culturesGram-negative rodsGentamicin susceptibilityInfantsTotal daysOutbreak investigationIdentical strainsNegative rodsUnique strainsHigh rateContour-clamped homogeneous electric field electrophoresisAdmissionGentamicin
1999
A Decade of Prevalence Surveys in a Tertiary-Care Center: Trends in Nosocomial Infection Rates, Device Utilization, and Patient Acuity
Weinstein J, Mazon D, Pantelick E, Reagan-Cirincione P, Dembry L, Hierholzer W. A Decade of Prevalence Surveys in a Tertiary-Care Center: Trends in Nosocomial Infection Rates, Device Utilization, and Patient Acuity. Infection Control And Hospital Epidemiology 1999, 20: 543-548. PMID: 10466554, DOI: 10.1086/501675.Peer-Reviewed Original ResearchConceptsNosocomial infection ratesAcute care patientsNosocomial bloodstream infectionsPrevalence surveyNosocomial infectionsInfection rateBloodstream infectionsPotential quality improvement initiativesAbnormal laboratory indicatorsAnnual prevalence surveysInvasive device utilizationTertiary care centerAbnormal laboratory valuesSeverity of illnessAcute care bedsInfection control practitionersSurveillance System dataRate of infectionQuality improvement initiativesObstetric-gynecologic servicesCase mix indexChart reviewCare patientsFoley catheterLaboratory indicators