2019
Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach.
Kachadourian LK, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach. The Primary Care Companion For CNS Disorders 2019, 21 PMID: 31050228, DOI: 10.4088/pcc.18m02402.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPositive affectMeasures of functioningCognitive functioningNegative thoughtsPTSD symptomsConcentration difficultiesSleep difficultiesTreatment of PTSDUS military veteransSeverity of PTSDPosttraumatic stress disorder (PTSD) symptomsSuicidal ideationDSM-5 PTSD symptomsMilitary veteransLifetime trauma burdenIrritability/aggressionHyperarousal symptomsDisorder symptomsStress disorderPsychogenic amnesiaPTSD diagnosisQuality of lifeMental functioningMost variancePharmacotherapies for PTSD and Substance Use Disorders
Kachadourian L, Jensen K, Sofuoglu M, Petrakis I. Pharmacotherapies for PTSD and Substance Use Disorders. 2019, 239-259. DOI: 10.4324/9781315442648-13.ChaptersOpioid use disorderAlcohol use disorderPosttraumatic stress disorderUse disordersPTSD/SUDPharmacological treatmentComorbid posttraumatic stress disorderUse of pharmacotherapySubstance use disordersEffectiveness of foodIntramuscular naltrexoneLabel medicationsEpidemiological studiesMedication developmentDrug AdministrationPharmacotherapyStress disorderAvailable evidenceDisordersNew targetsNaltrexoneTreatmentBiological mechanismsSpecific substancesSUD
2018
Protective correlates of suicidality among veterans with histories of posttraumatic stress disorder and major depressive disorder: Results from the National Health and Resilience in Veterans Study
Kachadourian LK, Tsai J, Harpaz-Rotem I, Southwick SM, Pietrzak RH. Protective correlates of suicidality among veterans with histories of posttraumatic stress disorder and major depressive disorder: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2018, 246: 731-737. PMID: 30616162, DOI: 10.1016/j.jad.2018.12.058.Peer-Reviewed Original ResearchMeSH KeywordsAdultCross-Sectional StudiesDepressive Disorder, MajorFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOptimismPrevalenceProtective FactorsResilience, PsychologicalRisk FactorsStress Disorders, Post-TraumaticSuicidal IdeationSuicideSuicide, AttemptedSurveys and QuestionnairesUnited StatesVeteransYoung AdultConceptsMajor depressive disorderPosttraumatic stress disorderProtective correlatesSuicidal ideationSuicide attemptsProtective factorsDepressive disorderNational HealthVeterans StudyMultivariable logistic regression analysisSuicidal behaviorStress disorderHistory of PTSDLogistic regression analysisSample of veteransAssessment of suicidalityLifetime suicide attemptsRisk factorsHigh-risk sampleTreatment approachesU.S. veteransWeb-based surveyCross-sectional natureSuicide riskSelf-report itemsNegative Affect Intensity and Hostility in Individuals With Alcohol Use Disorder With or Without Posttraumatic Stress Disorder
Gandelman E, Petrakis I, Kachadourian L, Ralevski E. Negative Affect Intensity and Hostility in Individuals With Alcohol Use Disorder With or Without Posttraumatic Stress Disorder. Journal Of Dual Diagnosis 2018, 14: 96-101. PMID: 29461925, DOI: 10.1080/15504263.2018.1434264.Peer-Reviewed Original ResearchConceptsNegative affect intensityPosttraumatic stress disorderComorbid alcohol use disorderAlcohol use disorderAffect intensityStress disorderHostility levelsUse disordersBuss-Durkee Hostility InventoryNegative affectPTSD symptomatologyDiagnosis severityAUD severityHostility InventorySymptomatology improvementHostilityHigh levelsPlacebo control groupParticipantsIndividualsDisordersFirst studyAffectSecondary analysisIntensity scaleSuicidal ideation in military veterans with alcohol dependence and PTSD: The role of hostility
Kachadourian LK, Gandelman E, Ralevski E, Petrakis IL. Suicidal ideation in military veterans with alcohol dependence and PTSD: The role of hostility. American Journal On Addictions 2018, 27: 124-130. PMID: 29489046, DOI: 10.1111/ajad.12688.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderSuicidal ideationAlcohol dependencePTSD symptom severityDepression symptomsMilitary veteransPlacebo-controlled treatment studySymptom severitySignificant public health problemComorbid posttraumatic stress disorderPublic health problemRelevant risk factorsRisk of suicideLifetime suicidal ideationUS military veteransRisk factorsTreatment approachesHealth problemsTreatment studiesRole of hostilityCovert hostilityStress disorderCivilian samplesVeteransIdeation
2017
Relationship between substance use and attitudes towards seeking professional psychological help among veterans filing PTSD claims
Meshberg-Cohen S, Kachadourian L, Black AC, Rosen MI. Relationship between substance use and attitudes towards seeking professional psychological help among veterans filing PTSD claims. Addictive Behaviors 2017, 74: 9-12. PMID: 28558337, DOI: 10.1016/j.addbeh.2017.05.024.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderSubstance use disordersPsychological helpCo-occurring substance use disordersProfessional Psychological Help-Short FormMale OEF/OIF veteransProfessional psychological helpSubstance useOEF/OIF veteransDemographic covariatesSample of veteransMental health treatmentStress disorderOIF veteransTreatment viewsTreatment attitudesHealth treatmentUse disordersFavorable attitudesVeteransBaseline assessmentAttitudesGeneral skepticismSubscale analysisComplicate treatment
2014
Trauma, PTSD, and binge and hazardous drinking among women and men: Findings from a national study
Kachadourian LK, Pilver CE, Potenza MN. Trauma, PTSD, and binge and hazardous drinking among women and men: Findings from a national study. Journal Of Psychiatric Research 2014, 55: 35-43. PMID: 24838049, PMCID: PMC4094352, DOI: 10.1016/j.jpsychires.2014.04.018.Peer-Reviewed Original ResearchConceptsPast-year posttraumatic stress disorderPosttraumatic stress disorderNon-binge drinkingHazardous drinkingBinge drinkingTrauma exposurePTSD statusAlcohol abuse/dependenceNon-hazardous drinkingPast-year bingeWave 2 National Epidemiologic SurveyAbuse/dependenceLifetime trauma exposurePatterns of drinkingNational Epidemiologic SurveyDrinking behaviorLogistic regression modelsSignificant gender-related differencesGender-related differencesTrauma-exposed individualsMultinomial logistic regression modelsGender-specific effectsPsychiatric comorbiditySocio-demographic covariatesMental health practitioners