Proton Pump Inhibitors and Bone Fractures?
Laine L. Proton Pump Inhibitors and Bone Fractures? The American Journal Of Gastroenterology 2009, 104: ajg200948. PMID: 19262543, DOI: 10.1038/ajg.2009.48.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnti-Ulcer AgentsCausalityDose-Response Relationship, DrugFractures, BoneHip FracturesHumansProton Pump InhibitorsRisk FactorsConceptsProton pump inhibitorsAverage daily dosePPI useHip fractureDaily dosePump inhibitorsReceptor antagonistContinuous proton-pump inhibitorsCase-control studyPotential confounding factorsDose-response relationshipLack of associationManitoba patientsAppropriate indicationsUK patientsCalcium absorptionFracture riskMEDLINE searchBone fracturesHigh dosesConfounding factorsCausal associationDuration responseRelevant articlesLonger duration