2021
Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy
Zakko A, Zakko L, Grimshaw AA, Laine L. Antiplatelet Monotherapy Is Associated with an Increased Risk of Bleeding After Endoscopic Sphincterotomy. Digestive Diseases And Sciences 2021, 67: 4161-4169. PMID: 34796411, DOI: 10.1007/s10620-021-07302-w.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyPost-sphincterotomy bleedingAntiplatelet monotherapyInclusion criteriaRisk of bleedingROBINS-I toolNewcastle-Ottawa ScaleHigh-quality studiesRandom-effects modelBackgroundClinical guidelinesAntithrombotic therapyAdult patientsCohort studyEndoscopic sphincterotomyPrimary outcomeAntiplatelet agentsOvid EmbaseRetrograde cholangiopancreatographyCochrane LibraryOvid MEDLINEMonotherapyMethodological qualityBleedingUnique citationsPatients
2005
Clinical Utility of Diagnostic Tests for Constipation in Adults: A Systematic Review
Rao S, Ozturk R, Laine L. Clinical Utility of Diagnostic Tests for Constipation in Adults: A Systematic Review. The American Journal Of Gastroenterology 2005, 100: ajg2005283. PMID: 15984989, DOI: 10.1111/j.1572-0241.2005.41845.x.Peer-Reviewed Original ResearchConceptsBlood testsDiagnostic testsSystematic reviewAnorectal manometry studyDiagnosis of constipationRetrospective endoscopic studySlow transit constipationAbdominal X-rayBalloon expulsion testColonic transit studyTransit constipationAnorectal manometryColonic transitEndoscopic studyBalloon expulsionBarium enemaProspective studyExpulsion testPhysiologic abnormalitiesHistorical controlsConstipationManometry studiesStudy populationAlarm featuresMethodological quality
2004
The hepatotoxicity of non‐steroidal anti‐inflammatory drugs
Rubenstein JH, Laine L. The hepatotoxicity of non‐steroidal anti‐inflammatory drugs. Alimentary Pharmacology & Therapeutics 2004, 20: 373-380. PMID: 15298630, DOI: 10.1111/j.1365-2036.2004.02092.x.Peer-Reviewed Original ResearchConceptsNon-steroidal anti-inflammatory drug usersNon-steroidal anti-inflammatory drugsAnti-inflammatory drugsLiver injuryDrug usersParticular non-steroidal anti-inflammatory drugsComparative riskPopulation-based epidemiological studyRare complicationExcess riskRelevant hepatotoxicityInclusion criteriaMethodological qualityEpidemiological studiesPrecise riskPatient countsCumulative exposureInjuryHospitalizationDrugsRiskHepatotoxicityIncidenceCurrent useDeath
1998
Has the impact of helicobacter pylori therapy on ulcer recurrence in the united states been overstated?
Laine L, Hopkins R, Girardi L. Has the impact of helicobacter pylori therapy on ulcer recurrence in the united states been overstated? The American Journal Of Gastroenterology 1998, 93: 1409. PMID: 9732917, DOI: 10.1111/j.1572-0241.1998.452_a.x.Peer-Reviewed Original ResearchConceptsH. pylori eradicationH. pylori therapyUlcer recurrencePylori eradicationPylori therapyH. pylori cureNon-NSAID ulcersCompletion of therapyHelicobacter pylori therapyUse of NSAIDsDuodenal ulcer patientsNorth American trialsUlcer recurrence rateHigh methodological qualityEndoscopic biopsy testsReview of abstractsEndoscopic followUlcer patientsDuodenal ulcerRelevant trialsRecurrence rateStudy inclusionOdds ratioCommon odds ratioMethodological quality