2007
Evaluation of Proton Pump Inhibitor Use in Patients With Acute Coronary Syndromes Based on Risk Factors for Gastrointestinal Bleed
Schreiner GC, Laine L, Murphy SA, Cannon CP. Evaluation of Proton Pump Inhibitor Use in Patients With Acute Coronary Syndromes Based on Risk Factors for Gastrointestinal Bleed. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2007, 6: 169-172. PMID: 18091407, DOI: 10.1097/hpc.0b013e318159921e.Peer-Reviewed Original ResearchConceptsUse of PPIsAcute coronary syndromeProton pump inhibitorsGI risk factorsRisk factorsCoronary syndromeHigh GI risk patientsProton pump inhibitor useNonsteroidal anti-inflammatory agentsInfection Therapy-ThrombolysisLong-term bleedingPrior GI eventsDual antiplatelet therapyUse of anticoagulantsAnti-inflammatory agentsAtorvastatin EvaluationAntiplatelet therapyGastrointestinal bleedGastrointestinal bleedingGI bleedingGI eventsInhibitor useRisk patientsTrials databasesPump inhibitors
1990
Multipolar electrocoagulation versus injection therapy in the treatment of bleeding peptic ulcers A prospective, randomized trial
Laine L. Multipolar electrocoagulation versus injection therapy in the treatment of bleeding peptic ulcers A prospective, randomized trial. Gastroenterology 1990, 99: 1303-1306. PMID: 2210238, DOI: 10.1016/0016-5085(90)91154-x.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationInjection therapyVisible vesselEndoscopic evidenceActive bleedingBloody nasogastric aspirateUpper gastrointestinal bleedHigh-risk patientsUnstable vital signsIncidence of surgeryTreatment of patientsCost of hospitalizationUnits of bloodFurther bleedingGastrointestinal bleedHospital stayNasogastric aspirateClinical evidencePeptic ulcerComparable efficacyMortality ratePatientsBleedingUlcers