2020
Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction
Vyas M, Celli R, Singh M, Patel N, Aslanian HR, Boffa D, Deng Y, Ciarleglio MM, Laine L, Jain D. Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction. Human Pathology 2020, 105: 67-73. PMID: 32941964, PMCID: PMC11152084, DOI: 10.1016/j.humpath.2020.08.007.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsBile refluxIntestinal metaplasiaReactive gastropathyGEJ regionMucosal injuryMucosal changesGastroesophageal junctionAntral intestinal metaplasiaDistal esophageal adenocarcinomaDetailed clinical historySex-matched patientsGastric antral biopsiesAnti-inflammatory drugsGastric bile refluxMucosal inflammationProximal stomachDistal esophagusMedication usePancreatic metaplasiaPathology databaseProximal gastricAntral biopsiesClinical historyGastric biopsies
1998
Evaluation of the FlexSure HP whole blood antibody test for diagnosis of Helicobacter pylori infection
Sadowski D, Cohen H, Laine L, Greenberg P, Goldstein J, Mihalov M, Cutler A. Evaluation of the FlexSure HP whole blood antibody test for diagnosis of Helicobacter pylori infection. The American Journal Of Gastroenterology 1998, 93: ajg1998490. PMID: 9820383, DOI: 10.1111/j.1572-0241.1998.00604.x.Peer-Reviewed Original ResearchConceptsHelicobacter pylori infectionRapid urease testPylori infectionWhole blood testH. pyloriWhole bloodBlood testsUrease testPositive rapid urease testBlood antibody testH. pylori infectionProton pump inhibitorsH. pylori diagnosisDetection of antibodiesUpper endoscopyStudy enrollmentPump inhibitorsGastric biopsiesIgG antibodiesSerum testAntibody testOffice testsAntral tissueBacterial infectionsPatients
1988
Histology of alcoholic hemorrhagic “gastritis”: A prospective evaluation
Laine L, Weinstein W. Histology of alcoholic hemorrhagic “gastritis”: A prospective evaluation. Gastroenterology 1988, 94: 1254-1262. PMID: 3258836, DOI: 10.1016/0016-5085(88)90661-0.Peer-Reviewed Original ResearchConceptsSubepithelial hemorrhageAlcoholic patientsHemorrhagic gastritisBiopsy specimensProminent inflammatory cell infiltrationFoveolar regionInflammatory cell infiltrateInflammatory cell infiltrationGastrointestinal bleedingUpper endoscopyCell infiltrateMucosal edemaProspective evaluationAdjacent mucosaBarrett's esophagusCell infiltrationGastric biopsiesHemorrhagic lesionsTarget lesionsHistologic natureHemorrhage scoreHistologic scoringBiopsy siteHemorrhagePatients