2015
Treatment of Refractory Gastrointestinal Strictures With Mitomycin C
Rustagi T, Aslanian HR, Laine L. Treatment of Refractory Gastrointestinal Strictures With Mitomycin C. Journal Of Clinical Gastroenterology 2015, 49: 837-847. PMID: 25626632, DOI: 10.1097/mcg.0000000000000295.Peer-Reviewed Original ResearchConceptsMitomycin C applicationMitomycin CGastrointestinal stricturesSystematic reviewLimited therapeutic interventionsAdditional randomized trialsLarge prospective studiesDifficult management problemSearch of MEDLINEBenign gastrointestinal stricturesTitles/abstractsCutaneous sclerosisAdverse eventsPartial responseComplete responseCaustic injuryRandomized trialsRefractory stricturesEsophageal strictureProspective studyEmbase databasesCommon siteEffective therapyInclusion criteriaOptimal dose
1995
Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis.
Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Annals Of Internal Medicine 1995, 123: 280-7. PMID: 7611595, DOI: 10.7326/0003-4819-123-4-199508150-00007.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingTreatment of patientsEndoscopic ligationVariceal bleedingEsophageal varicesEndoscopic treatmentDuplicate data abstractionDuplicate independent reviewEndoscopic treatment sessionsRate of deathRelevant primary articlesReview of citationsVariceal obliterationBacterial peritonitisLigation therapyPulmonary infectionEsophageal strictureMethodologic qualitySclerotherapyMortality rateTreatment sessionsPatientsRelevant articlesPrimary investigatorUnpublished studies
1993
Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices.
Laine L, el-Newihi HM, Migikovsky B, Sloane R, Garcia F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Annals Of Internal Medicine 1993, 119: 1-7. PMID: 8498757, DOI: 10.7326/0003-4819-119-1-199307010-00001.Peer-Reviewed Original ResearchConceptsRisk of deathEsophageal varicesVariceal eradicationEndoscopic examinationLigation groupInitial endoscopic examinationUrban county hospitalKaplan-Meier estimatesLigation treatmentTransfusion requirementsVariceal obliterationFurther bleedingHospital stayEndoscopic sclerotherapyEndoscopic therapyEsophageal ulcerLocal complicationsRecurrent varicesBlood transfusionSevere bleedingEndoscopic ligationTreatment failureEsophageal strictureCounty HospitalSclerotherapy