2019
Update on Obstetric Hemorrhage
Reale S, Leffert L, Farber M. Update on Obstetric Hemorrhage. Current Anesthesiology Reports 2019, 9: 60-68. DOI: 10.1007/s40140-019-00311-6.Peer-Reviewed Original ResearchPostpartum hemorrhageObstetric hemorrhageRecent evidence-based advancesEarly fibrinogen replacementPreventable maternal morbidityTranexamic acid therapyMassive transfusion protocolRecent epidemiologic dataEvidence-based advancesPostpartum hemorrhage managementConsensus BundleMaternal morbidityTransfusion protocolTransfusion strategyBlood lossAcid therapyEpidemiologic dataFibrinogen replacementHemorrhageHemorrhage managementImportant causeProtocol useEnhanced risk assessmentMorbidityNational Partnership
2018
The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality
McQUAID E, Leffert LR, Bateman BT. The Role of the Anesthesiologist in Preventing Severe Maternal Morbidity and Mortality. Clinical Obstetrics & Gynecology 2018, 61: 372-386. PMID: 29319586, DOI: 10.1097/grf.0000000000000350.Peer-Reviewed Original ResearchMeSH KeywordsAirway ManagementAnesthesia, EpiduralAnesthesia, GeneralAnesthesiologistsAnesthetics, LocalBlood TransfusionEchocardiographyEpidural AbscessFemaleHeadacheHematoma, Epidural, SpinalHumansIntubation, IntratrachealMaternal DeathMeningitisMonitoring, PhysiologicObstetric Labor ComplicationsPhysician's RolePregnancyPuerperal DisordersRespiratory AspirationRisk FactorsConceptsObstetric anesthesiologistSevere maternal morbidityLife-saving interventionsMaternal morbidityCesarean deliveryUnstable patientsGeneral anesthesiaObstetric suiteObstetric proceduresBedside managementClinical scenariosAnesthesiologistsIntensivistsAnesthesiaGreater experienceDeliveryAnalgesiaMorbidityPatientsUnique roleMortalityClinicians
2017
The Validity of Discharge Billing Codes Reflecting Severe Maternal Morbidity
Sigakis M, Leffert L, Mirzakhani H, Sharawi N, Rajala B, Callaghan W, Kuklina E, Creanga A, Mhyre J, Bateman B. The Validity of Discharge Billing Codes Reflecting Severe Maternal Morbidity. Obstetric Anesthesia Digest 2017, 37: 16-17. DOI: 10.1097/01.aoa.0000512008.03839.93.Peer-Reviewed Original ResearchMassachusetts General HospitalPositive predictive valueMaternal morbiditySevere maternal complicationsSevere maternal morbidityHospital discharge dataMichigan Health SystemMaternal complicationsGeneral HospitalDiseases codesBilling codesAcademic centersPredictive valueICD codesHealth systemMorbidityPresent studyDischarge dataComplicationsHospitalAnesthetic and Obstetric Management of Placenta Accreta: Clinical Experience and Available Evidence
Toledano R, Leffert L. Anesthetic and Obstetric Management of Placenta Accreta: Clinical Experience and Available Evidence. Current Anesthesiology Reports 2017, 7: 93-102. DOI: 10.1007/s40140-017-0200-2.Peer-Reviewed Original ResearchPlacenta accretaObstetric managementManagement of womenCesarean delivery rateTiming of deliveryPeripartum hysterectomyAdherent placentaMaternal hemorrhageNeuraxial anesthesiaHigh morbidityConsensus guidelinesPatient preferencesLeading causeMultidisciplinary planningCommon causeAccretaClinician experienceAntenatal diagnosisClinical experienceMultidisciplinary teamInterventional radiologyEmergency deliveryAvailable evidenceMorbidityCurrent literature
2016
The Validity of Discharge Billing Codes Reflecting Severe Maternal Morbidity
Sigakis MJ, Leffert LR, Mirzakhani H, Sharawi N, Rajala B, Callaghan WM, Kuklina EV, Creanga AA, Mhyre JM, Bateman BT. The Validity of Discharge Billing Codes Reflecting Severe Maternal Morbidity. Anesthesia & Analgesia 2016, 123: 731-738. PMID: 27387839, PMCID: PMC7481827, DOI: 10.1213/ane.0000000000001436.Peer-Reviewed Original ResearchConceptsICD-9-CM codesSevere maternal morbidityPositive predictive valueMaternal morbidityMassachusetts General HospitalMichigan Health SystemGeneral HospitalClinical categoriesHealth systemCorresponding medical chartsConfidence intervalsLower confidence limitAnesthesia complicationsDelivery hospitalizationsObstetric categoryDelivery admissionMedical chartsDischarge diagnosisDiseases codesClinical dataLaboratory valuesBilling codesInternational ClassificationMorbidityBilling records
2015
What’s new in obstetric anesthesia? Focus on preeclampsia
Leffert L. What’s new in obstetric anesthesia? Focus on preeclampsia. International Journal Of Obstetric Anesthesia 2015, 24: 264-271. PMID: 25936785, DOI: 10.1016/j.ijoa.2015.03.008.Peer-Reviewed Original ResearchConceptsMulti-organ systemsHigh-risk patientsPrevalence of preeclampsiaDefinition of preeclampsiaObstetric care teamPregnant patientsFetal effectsObstetric anesthesiaClinical managementCare teamPreeclampsiaTherapeutic interventionsPatientsContemporary dataRecent updatesComorbiditiesMorbidityPregnancyAnesthesiaPathogenesisEtiologyFetusesPrevalenceDiagnosisCare
2012
Influence of Patient Comorbidities on the Risk of Near-Miss Maternal Morbidity or Mortality
Mhyre J, Bateman B, Leffert L. Influence of Patient Comorbidities on the Risk of Near-Miss Maternal Morbidity or Mortality. Obstetric Anesthesia Digest 2012, 32: 212-213. DOI: 10.1097/01.aoa.0000422690.35910.a1.Peer-Reviewed Original Research