2015
Hypertensive Disorders and Pregnancy-Related Stroke
Leffert LR, Clancy CR, Bateman BT, Bryant AS, Kuklina EV. Hypertensive Disorders and Pregnancy-Related Stroke. Obstetrics And Gynecology 2015, 125: 124-131. PMID: 25560114, PMCID: PMC4445352, DOI: 10.1097/aog.0000000000000590.Peer-Reviewed Original ResearchConceptsTraditional stroke risk factorsPregnancy-associated strokeHypertensive disordersPregnancy hospitalizationsStroke risk factorsStroke-related complicationsStroke riskRisk factorsOdds ratioNationwide Inpatient SampleCongenital heart diseaseCross-sectional studyComplication rateStroke hospitalizationsInpatient SampleHeart diseaseNationwide rateHospitalizationPregnancyStrokeLogistic regressionCongenital coagulationDisordersConfidence intervalsComplications
2014
Opioid Abuse and Dependence during Pregnancy
Maeda A, Bateman BT, Clancy CR, Creanga AA, Leffert LR. Opioid Abuse and Dependence during Pregnancy. Anesthesiology 2014, 121: 1158-1165. PMID: 25405293, DOI: 10.1097/aln.0000000000000472.Peer-Reviewed Original ResearchConceptsOpioid abuseObstetrical outcomesIntrauterine growth restrictionNationwide Inpatient SampleObstetrical morbidityPlacental abruptionPreterm laborCesarean deliveryMaternal deathsPremature rupturePregnant womenCardiac arrestRelevant confoundersInpatient SampleGrowth restrictionPreventive strategiesTherapeutic interventionsPregnancyLogistic regressionNationwide trendsHospitalizationPrevalenceAbuseOutcomesUnited StatesCardiac Arrest during Hospitalization for Delivery in the United States, 1998–2011
Mhyre JM, Tsen LC, Einav S, Kuklina EV, Leffert LR, Bateman BT. Cardiac Arrest during Hospitalization for Delivery in the United States, 1998–2011. Anesthesiology 2014, 120: 810-818. PMID: 24694844, PMCID: PMC4445354, DOI: 10.1097/aln.0000000000000159.Peer-Reviewed Original ResearchConceptsAmniotic fluid embolismCardiac arrestPotential etiologiesHeart failureCommon potential etiologyMaternal cardiac arrestNationwide Inpatient SampleDemographic risk factorsMaternal cardiopulmonary arrestHospital dischargeCardiopulmonary arrestU.S. hospitalizationsUnderlying etiologyInpatient SampleMaternal arrestRisk factorsHospitalizationSurvival rateEtiologySepsisEmbolismHemorrhageArrestPatientsSurvival
2012
Outcomes of hospitalization in pregnant women with CNS neoplasms: a population-based study
Terry AR, Barker FG, Leffert L, Bateman BT, Souter I, Plotkin SR. Outcomes of hospitalization in pregnant women with CNS neoplasms: a population-based study. Neuro-Oncology 2012, 14: 768-776. PMID: 22513749, PMCID: PMC3367848, DOI: 10.1093/neuonc/nos078.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBostonBrain NeoplasmsCesarean SectionChildDelivery, ObstetricFemaleFetal Growth RetardationFollow-Up StudiesHospitalizationHumansMaternal MortalityObstetric Labor, PrematurePregnancyPregnancy Complications, NeoplasticPregnancy OutcomeRetrospective StudiesRisk FactorsSpinal NeoplasmsSurvival RateYoung AdultConceptsBenign brain tumorsIntrauterine growth restrictionMalignant brain tumorsNationwide Inpatient SamplePopulation-based studyCNS neoplasmsBrain tumorsCaesarean deliveryPreterm laborSpine tumorsPregnancy outcomesMaternal mortalityPregnancy-related admissionsAdverse pregnancy outcomesRetrospective cohort studyOutcomes of hospitalizationLogistic regression modelsPregnancy complicationsCohort studyHyperemesis gravidarumSurgical patientsObstetric riskPregnant womenInpatient SampleGrowth restrictionPeripartum Subarachnoid Hemorrhage
Bateman B, Olbrecht V, Berman M, Minehart R, Schwamm L, Leffert L. Peripartum Subarachnoid Hemorrhage. Anesthesiology 2012, 116: 324-333. PMID: 22166951, DOI: 10.1097/aln.0b013e3182410b22.Peer-Reviewed Original ResearchConceptsSubarachnoid hemorrhageHypertensive disordersRisk factorsPregnancy-related admissionsIndependent risk factorIntracranial venous thrombosisNationwide Inpatient SampleAfrican American raceVariety of etiologiesRange of etiologiesSickle cell diseaseIdentified admissionsHospital deathMaternal morbidityNonpregnant patientsNonpregnant womenIndependent predictorsMalignant etiologySevere headacheVenous thrombosisNonpregnant controlsPregnancy resultsVenous bleedingInstitution experienceInpatient Sample
2011
Influence of Patient Comorbidities on the Risk of Near-miss Maternal Morbidity or Mortality
Mhyre J, Bateman B, Leffert L. Influence of Patient Comorbidities on the Risk of Near-miss Maternal Morbidity or Mortality. Anesthesiology 2011, 115: 963-972. PMID: 21934482, DOI: 10.1097/aln.0b013e318233042d.Peer-Reviewed Original ResearchConceptsNear-miss morbidityMorbidity/mortalityMaternal morbidityNear-miss maternal morbidityImportant medical comorbiditiesEnd-organ injuryHigh-quality intrapartum careSystemic lupus erythematosusNationwide Inpatient SampleHigh-risk groupLength of stayMiss morbidityMedical comorbiditiesObstetric complicationsPulmonary hypertensionPatient comorbiditiesLupus erythematosusIntrapartum carePregnant womenNational burdenInpatient SampleMaternal characteristicsObstetric diseasesPublic health investmentDelivery outcomes
2010
The Epidemiology of Postpartum Hemorrhage in a Large, Nationwide Sample of Deliveries
Bateman BT, Berman MF, Riley LE, Leffert LR. The Epidemiology of Postpartum Hemorrhage in a Large, Nationwide Sample of Deliveries. Anesthesia & Analgesia 2010, 110: 1368-1373. PMID: 20237047, DOI: 10.1213/ane.0b013e3181d74898.Peer-Reviewed Original ResearchConceptsPostpartum hemorrhageUterine atonyRisk factorsCesarean deliveryRate of PPHCases of PPHIncidence of PPHSubstantial maternal morbidityIndependent risk factorClinical Modification codesNationwide Inpatient SampleLogistic regression modelingAntepartum haemorrhageDelivery complicationsHospital deathMaternal morbidityMaternal outcomesMultiple gestationsCommon complicationHospital admissionHypertensive diseaseCommon etiologyMaternal ageInpatient SampleContemporary epidemiology