Featured Publications
Evaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods
Han L, Goulet JL, Skanderson M, Bathulapalli H, Luther SL, Kerns RD, Brandt CA. Evaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods. Pain Medicine 2018, 20: 90-102. PMID: 29584926, PMCID: PMC6329442, DOI: 10.1093/pm/pny027.Peer-Reviewed Original ResearchConceptsIntegrative health approachesPS matchingCIH exposureMusculoskeletal painPropensity score methodsSelf-rated pain intensityHealth approachHigher pain intensity ratingsPain intensity outcomesChronic musculoskeletal painPain intensity ratingsIPTW modelsRetrospective cohortPain intensityChronic painClinical visitsInitial diagnosisChiropractic careUS veteransBaseline differencesTreatment weightingExposure groupPainScore methodTreatment effectivenessOpioid dosing trends over eight years among US Veterans with musculoskeletal disorders after returning from service in support of recent conflicts
Han L, Allore H, Goulet J, Bathulapali H, Skanderson M, Brandt C, Haskell S, Krebs E. Opioid dosing trends over eight years among US Veterans with musculoskeletal disorders after returning from service in support of recent conflicts. Annals Of Epidemiology 2017, 27: 563-569.e3. PMID: 28890282, PMCID: PMC5647654, DOI: 10.1016/j.annepidem.2017.08.015.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnalgesics, OpioidChronic PainDrug PrescriptionsElectronic PrescribingFemaleHumansMaleMental HealthMiddle AgedMusculoskeletal DiseasesOpioid-Related DisordersPrescription DrugsStress Disorders, Post-TraumaticUnited StatesUnited States Department of Veterans AffairsVeteransVeterans HealthYoung AdultConceptsHigh-dose prescribingOpioid prescriptionsMental health diagnosesMusculoskeletal disordersDaily morphine equivalentsHealth diagnosisHigh-dose therapyLong-term opioidsHigh-dose prescriptionsAverage daily dosePosttraumatic stress disorderMorphine equivalentsDose therapyDaily dosePatient characteristicsChronic painUS veteransOdds ratioPrescribingStress disorderBaseline periodGeographic confoundingVeteransPrescriptionOpioids
2024
Leveraging Electronic Health Records to Assess Residential Mobility Among Veterans in the Veterans Health Administration
Wang K, Hendrickson Z, Miller M, Abel E, Skanderson M, Erdos J, Womack J, Brandt C, Desai M, Han L. Leveraging Electronic Health Records to Assess Residential Mobility Among Veterans in the Veterans Health Administration. Medical Care 2024, 62: 458-463. PMID: 38848139, DOI: 10.1097/mlr.0000000000002017.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationElectronic health recordsResidential addressesHealth recordsHealth AdministrationLeveraging electronic health recordsInfluence health care utilizationVeterans Health Administration dataAssociations of sociodemographicsHealth care utilizationHealth care systemPatient's residential addressCross-sectional analysisGeneralized logistic regressionCare utilizationHealth systemResidential mobilitySubstance use disordersCare systemPatient's residenceLogistic regressionVeteransMultinomial outcomesHealthOdds
2022
Multimorbidity measures differentially predicted mortality among older Chinese adults
Yao SS, Xu HW, Han L, Wang K, Cao GY, Li N, Luo Y, Chen YM, Su HX, Chen ZS, Huang ZT, Hu YH, Xu B. Multimorbidity measures differentially predicted mortality among older Chinese adults. Journal Of Clinical Epidemiology 2022, 146: 97-105. PMID: 35259446, DOI: 10.1016/j.jclinepi.2022.03.002.Peer-Reviewed Original ResearchConceptsNet reclassification indexIntegrated discrimination improvementMultimorbidity measuresMortality prediction modelOlder Chinese adultsMultimorbidity patternsC-statisticCondition countMortality predictionChinese adultsMultimorbidity trajectoriesNet reclassification improvementCox regressionReclassification improvementReclassification indexChronic conditionsDiscrimination improvementMortality riskHigh riskIntegrated discriminationMultimorbidityStudy designMortalityAdultsAge
2021
Functional Disability Among Older Versus Younger Adults With Advanced Non–Small-Cell Lung Cancer
Presley CJ, Arrato NA, Janse S, Shields PG, Carbone DP, Wong ML, Han L, Gill TM, Allore HG, Andersen BL. Functional Disability Among Older Versus Younger Adults With Advanced Non–Small-Cell Lung Cancer. JCO Oncology Practice 2021, 17: e848-e858. PMID: 33939536, PMCID: PMC8258136, DOI: 10.1200/op.20.01004.Peer-Reviewed Original ResearchConceptsBaseline disabilityFunctional disabilityAdvanced NSCLCBrain metastasesLung cancerHigher oddsUsual activitiesDepressive symptomsEastern Cooperative Oncology Group performance statusAdvanced non-small cell lung cancerNon-small cell lung cancerDisability groupsECOG PS 0Poor ECOG PSCell lung cancerFunctional status scoresECOG PSPatient characteristicsPerformance statusProspective cohortPS 0Systemic treatmentEuroQol-5DPsychologic symptomsDisease characteristics
2019
Associations between home deaths and end-of-life nursing care trajectories for community-dwelling people: a population-based registry study
Kjellstadli C, Han L, Allore H, Flo E, Husebo BS, Hunskaar S. Associations between home deaths and end-of-life nursing care trajectories for community-dwelling people: a population-based registry study. BMC Health Services Research 2019, 19: 698. PMID: 31615500, PMCID: PMC6794846, DOI: 10.1186/s12913-019-4536-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolContinuity of Patient CareFemaleHome Care ServicesHome NursingHospice CareHospitalsHumansIndependent LivingInfantInfant, NewbornLogistic ModelsLongitudinal StudiesMaleMiddle AgedNorwayNursing CarePalliative CareRegistriesResearch DesignRetrospective StudiesSkilled Nursing FacilitiesTerminal CareYoung AdultConceptsSkilled nursing facilitiesHome deathCommunity-dwelling peoplePlace of deathHome nursingSNF stayAssociation of placeNursing servicesPopulation-based registry studyHome nursing servicesPalliative home careContinuity of careRetrospective longitudinal studyDays of lifeMunicipal healthcare servicesLogistic regression modelsGroup-based trajectory modelsDeath RegistryMultinomial logistic regression modelsNorwegian CauseRegistry studyBackgroundFew studiesNational registryCare trajectoriesNursing hours
2018
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium
Knauert MP, Gilmore EJ, Murphy TE, Yaggi HK, Van Ness PH, Han L, Hirsch LJ, Pisani MA. Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. Journal Of Critical Care 2018, 48: 124-129. PMID: 30179762, PMCID: PMC6226351, DOI: 10.1016/j.jcrc.2018.08.028.Peer-Reviewed Original ResearchConceptsICU patientsIll patientsOdds ratioHigher oddsSleep spindlesIntensive care unit outcomesGrade of encephalopathySignificant sleep disruptionWorse ICU outcomeMedical ICU patientsAcute brain injuryObservational cohort studySedative-hypnotic useImportant prognostic valueLength of stayStage N2 sleepK-complexesCohort studyCritical illnessHospital dischargeRankin ScaleICU outcomesPrognostic valueSevere gradesMedical records
2014
Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions
Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H. Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions. PLOS ONE 2014, 9: e90733. PMID: 24614535, PMCID: PMC3948696, DOI: 10.1371/journal.pone.0090733.Peer-Reviewed Original ResearchConceptsMultiple chronic conditionsAnti-hypertensive treatmentCardiovascular eventsAnti-hypertensive medicationsHigh-intensity groupChronic conditionsOlder adultsHazard ratioPropensity scoreIntensity groupStandardized daily doseCommunity-living participantsPropensity score adjustmentCV eventsMedication intensityLess comorbidityDaily doseRandomized trialsMAIN OUTCOMERepresentative cohortScore adjustmentSurvey cohortRCT resultsCohortMortality
2002
Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia
Cole MG, McCusker J, Dendukuri N, Han L. Symptoms of Delirium Among Elderly Medical Inpatients With or Without Dementia. Journal Of Neuropsychiatry 2002, 14: 167-175. PMID: 11983791, DOI: 10.1176/jnp.14.2.167.Peer-Reviewed Original Research