2023
Relationship Between Distressing Symptoms and Changes in Disability After Major Surgery Among Community-living Older Persons
Gill T, Han L, Feder S, Gahbauer E, Leo-Summers L, Becher R. Relationship Between Distressing Symptoms and Changes in Disability After Major Surgery Among Community-living Older Persons. Annals Of Surgery 2023, 279: 65-70. PMID: 37389893, PMCID: PMC10761592, DOI: 10.1097/sla.0000000000005984.Peer-Reviewed Original ResearchConceptsMajor surgeryDistressing symptomsElective surgeryFunctional outcomeOlder personsCommunity-living older personsMultiple distressing symptomsSocioeconomic disadvantageCommunity-living personsTiming of surgerySerious health eventsNumber of disabilitiesSurgerySignificant associationSymptomsHealth eventsRate ratioPotential targetDisabilityUnit increaseDeleterious effectsOutcomesPersonsMultimorbidityAdmission
2022
Multimorbidity measures differentially predicted mortality among older Chinese adults
Yao SS, Xu HW, Han L, Wang K, Cao GY, Li N, Luo Y, Chen YM, Su HX, Chen ZS, Huang ZT, Hu YH, Xu B. Multimorbidity measures differentially predicted mortality among older Chinese adults. Journal Of Clinical Epidemiology 2022, 146: 97-105. PMID: 35259446, DOI: 10.1016/j.jclinepi.2022.03.002.Peer-Reviewed Original ResearchConceptsNet reclassification indexIntegrated discrimination improvementMultimorbidity measuresMortality prediction modelOlder Chinese adultsMultimorbidity patternsC-statisticCondition countMortality predictionChinese adultsMultimorbidity trajectoriesNet reclassification improvementCox regressionReclassification improvementReclassification indexChronic conditionsDiscrimination improvementMortality riskHigh riskIntegrated discriminationMultimorbidityStudy designMortalityAdultsAgePatterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese
Huang ZT, Luo Y, Han L, Wang K, Yao SS, Su HX, Chen S, Cao GY, De Fries CM, Chen ZS, Xu HW, Hu YH, Xu B. Patterns of cardiometabolic multimorbidity and the risk of depressive symptoms in a longitudinal cohort of middle-aged and older Chinese. Journal Of Affective Disorders 2022, 301: 1-7. PMID: 34999125, DOI: 10.1016/j.jad.2022.01.030.Peer-Reviewed Original ResearchConceptsCardiometabolic multimorbidityCardiometabolic diseasesHeart diseaseDepressive symptomsSelf-reported chronic conditionsEpidemiological Studies Depression ScaleAbsence of strokeRisk of depressionRetirement Longitudinal Study 2011Multiple cardiometabolic diseasesDose effectMental health preventionOlder ChineseAdditive effectChronic conditionsDisease combinationsLongitudinal cohortDepression ScaleHigh riskMultimorbidityPerson-centered healthcareDiabetesSymptomsHealth preventionChina Health
2020
Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adults
Liu Z, Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity in Chinese older adults. Innovation In Aging 2020, 4: 908-909. PMCID: PMC7741254, DOI: 10.1093/geroni/igaa057.3342.Peer-Reviewed Original ResearchChinese older adultsAdverse health outcomesCognitive frailtyHealth outcomesInstrumental ADLOlder adultsPhysical frailtyCognitive impairmentInternational Consensus GroupRetirement Longitudinal StudyPhysical frailty assessmentFrailty assessmentIADL disabilitySecondary preventionDaily livingHigh riskMobility disabilityMultimorbidityConsensus groupFrailtyChina HealthNormal cognitionBaseline cognitionHealthy agingDeathCognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study
Chen C, Park J, Wu C, Xue Q, Agogo G, Han L, Hoogendijk EO, Liu Z, Wu Z. Cognitive frailty in relation to adverse health outcomes independent of multimorbidity: results from the China health and retirement longitudinal study. Aging 2020, 12: 23129-23145. PMID: 33221750, PMCID: PMC7746379, DOI: 10.18632/aging.104078.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAge FactorsAgedAged, 80 and overChinaCognitionCognitive AgingCognitive DysfunctionDisability EvaluationFemaleFrail ElderlyFrailtyFunctional StatusHealth SurveysHospitalizationHumansLongitudinal StudiesMaleMiddle AgedMobility LimitationMultimorbidityPrognosisRetirementRisk AssessmentRisk FactorsConceptsCognitive frailtyInstrumental ADLPhysical frailtyHealth outcomesCognitive impairmentAdverse health outcomesRetirement Longitudinal StudyPhysical frailty assessmentChinese older adultsFrailty assessmentIADL disabilitySecondary preventionDaily livingHigh riskMobility disabilityMultimorbidityFrailtyChina HealthNormal cognitionBaseline cognitionHealthy agingOlder adultsDeathBasic activitiesHospitalizationAssociations between Multimorbidity and Physical Performance in Older Chinese Adults
Yao SS, Meng X, Cao GY, Huang ZT, Chen ZS, Han L, Wang K, Su HX, Luo Y, Hu Y, Xu B. Associations between Multimorbidity and Physical Performance in Older Chinese Adults. International Journal Of Environmental Research And Public Health 2020, 17: 4546. PMID: 32599778, PMCID: PMC7344642, DOI: 10.3390/ijerph17124546.Peer-Reviewed Original ResearchConceptsSlow gait speedMultimorbidity patternsGait speedGrip strengthOlder Chinese adultsPhysical performanceHighest quartileChronic conditionsLowest quartileChinese adultsWorse physical performanceMaximum grip strengthRetirement Longitudinal Study 2011Average gait speedHealth care servicesMultimorbid populationClinical guidelinesOdds ratioMultimorbidityClinical settingChina HealthQuartileOlder adultsClinical performanceIncreased numberMultimorbidity among Two Million Adults in China
Wang X, Yao S, Wang M, Cao G, Chen Z, Huang Z, Wu Y, Han L, Xu B, Hu Y. Multimorbidity among Two Million Adults in China. International Journal Of Environmental Research And Public Health 2020, 17: 3395. PMID: 32414117, PMCID: PMC7277827, DOI: 10.3390/ijerph17103395.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseCerebrovascular diseaseMultimorbidity patternsMultimorbidity prevalenceBeijing Medical Claim DataMedical claims dataMiddle-aged groupOlder Chinese individualsMillion adultsMorbidity treatmentOlder patientsRheumatoid arthritisPreventive careHeart diseaseChronic diseasesClaims dataHypertensionOlder groupOlder adultsStrong associationDiseaseCOPDMultimorbidityChinese individualsAppropriate guidelines
2019
Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study
Yao SS, Cao GY, Han L, Chen ZS, Huang ZT, Gong P, Hu Y, Xu B. Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study. The Journals Of Gerontology Series A 2019, 75: 1974-1980. PMID: 31406983, DOI: 10.1093/gerona/glz185.Peer-Reviewed Original ResearchConceptsPatterns of multimorbidityPrevalence of multimorbidityMultimorbidity patternsRetirement Longitudinal StudyOlder ChineseChina HealthPopulation-based studyDemographic characteristicsIndividual chronic diseasesLongitudinal studyCommon multimorbidity patternsLogistic regression modelsParticipants' demographic characteristicsNationally Representative SampleEntire cohortPotential confoundersChronic diseasesRepresentative sampleMultimorbidityAlcohol consumptionMemory-related diseasesUrban-rural differencesPrevalenceInterventional implicationsResidential region
2018
MULTIMORBIDITY PATTERNS AND ASSOCIATIONS WITH FUNCTIONAL OUTCOMES AMONG OLDER CHINESE
Xu B, Han L, Li M, Cao G, Yao S, Hu Y. MULTIMORBIDITY PATTERNS AND ASSOCIATIONS WITH FUNCTIONAL OUTCOMES AMONG OLDER CHINESE. Innovation In Aging 2018, 2: 498-498. PMCID: PMC6228077, DOI: 10.1093/geroni/igy023.1855.Peer-Reviewed Original ResearchChronic conditionsMultimorbidity patternsFunctional outcomeHandgrip strengthChina HealthPatterns of multimorbidityMultiple chronic conditionsIntegrated care planMaximum handgrip strengthHandgrip strength valuesRetirement Longitudinal StudyLower cognitive scoresOlder patientsFunctional statusOverall prevalenceCare plansElevated riskNutrition SurveyClinical problemClinical decisionChinese populationCognitive functionMultimorbidityCognitive scoresLongitudinal study