The Temporal Relationship Between Depression Symptoms and Cognitive Functioning in Older Medical Patients—Prospective or Concurrent?
Han L, McCusker J, Abrahamowicz M, Cole M, Capek R. The Temporal Relationship Between Depression Symptoms and Cognitive Functioning in Older Medical Patients—Prospective or Concurrent? The Journals Of Gerontology Series A 2006, 61: 1319-1323. PMID: 17234828, DOI: 10.1093/gerona/61.12.1319.Peer-Reviewed Original ResearchConceptsMini-Mental State ExaminationHamilton Depression Rating ScaleHDRS scoresDepression symptomsCognitive impairmentInpatients 65 yearsIndependent risk factorTime pointsOlder medical patientsDepression Rating ScaleOld-age depressionLower MMSE scoresSame time pointsCognitive functioningSubsequent time pointsOne-point increaseTemporal relationshipCardiovascular riskMMSE changeIllness severityMedical patientsRisk factorsMMSE scoresDepressive symptomsEpidemiological studiesRecoverable Cognitive Dysfunction at Hospital Admission in Older Persons During Acute Illness
Inouye SK, Zhang Y, Han L, Leo‐Summers L, Jones R, Marcantonio E. Recoverable Cognitive Dysfunction at Hospital Admission in Older Persons During Acute Illness. Journal Of General Internal Medicine 2006, 21: 1276-1281. PMID: 16965558, PMCID: PMC1924736, DOI: 10.1111/j.1525-1497.2006.00613.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAcute DiseaseAgedAged, 80 and overCognition DisordersCohort StudiesDeliriumDementiaEducational StatusFemaleHospitalizationHumansIncidenceMalePredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesRecovery of FunctionSeverity of Illness IndexConceptsMini-Mental State ExaminationCognitive dysfunctionAcute illnessOlder personsProspective cohort studyAdjusted odds ratioHigher illness severityPotential clinical implicationsMajority of casesHigher educational levelCohort studyHospital admissionPrimary outcomeIllness severityMultivariable analysisConsecutive admissionsOdds ratioAcademic hospitalFunctional impairmentMMSE scoresState ExaminationDeliriumMMSE impairmentDysfunctionPatients