2023
Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdults
2021
Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US Veterans
Allore HG, Gnjidic D, Skanderson M, Han L. Association Between Potentially Inappropriate Medications and 30-Day Post–Hospital Discharge Outcomes in US Veterans. Annals Of Pharmacotherapy 2021, 56: 256-263. PMID: 34282638, PMCID: PMC8770754, DOI: 10.1177/10600280211032072.Peer-Reviewed Original ResearchConceptsAdjusted hazard ratioRisk of mortalityHospital dischargeMean ageAcute care hospital readmissionPrimary care clinic visitsCohort's mean agePrevalence of PIMsInappropriate medication useRisk of readmissionHospital discharge outcomesEmergency room visitsHealth care utilizationAdverse drug eventsCentral nervous systemCause mortalityInappropriate medicationsPIM useClinic visitsHazard ratioProspective cohortDischarge outcomesHospital readmissionMedication useOlder inpatients
2013
The impact of medication use on symptom burden in older patients with multiple medical morbidities
Han M, Tinetti M, Agostini J, Han L, Lee H, Walke L. The impact of medication use on symptom burden in older patients with multiple medical morbidities. Journal Of Clinical Gerontology And Geriatrics 2013, 4: 84-88. DOI: 10.1016/j.jcgg.2013.03.002.Peer-Reviewed Original ResearchSymptom burdenMedical morbidityMedication useVeterans Affairs primary care clinicsGreater medication useMultiple medical morbiditiesNumber of medicationsMedical record reviewPrimary care clinicsSurvey of patientsAdverse drug eventsCross-sectional studySeverity of symptomsAdditional medicationOlder patientsCare clinicsRecord reviewRoutine appointmentsDrug eventsChi-square analysisMorbiditySevere symptomsMedicationsLinear regression analysisSymptom categories