2023
Clinical features in adults with acquired cutis laxa: a retrospective review
O’Connell K, Schaefer M, Atzmony L, Vleugels R, Choate K, LaChance A, Min M. Clinical features in adults with acquired cutis laxa: a retrospective review. British Journal Of Dermatology 2023, 188: 800-816. PMID: 36849736, PMCID: PMC10230959, DOI: 10.1093/bjd/ljad043.Peer-Reviewed Original ResearchConceptsAcquired cutis laxaCutis laxaThorough systemic investigationRare dermatological conditionMedication exposureAdult patientsRetrospective reviewPatient historyDermatological conditionsGenetic predispositionGenetic mutationsPatientsSystemic investigationEnvironmental insultsExposureComorbiditiesEtiologyInsultLaxaSymptomatology
2022
Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders
Atzmony L, Ugwu N, Hamilton C, Paller A, Zech L, Antaya R, Choate K. Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders. Pediatric Dermatology 2022, 39: 903-907. PMID: 35853659, PMCID: PMC9712156, DOI: 10.1111/pde.15094.Peer-Reviewed Original ResearchConceptsInflammatory linear verrucous epidermal nevusVerrucous epidermal nevusEpidermal nevusCARD14 mutationsHotspot mutationsLinear verrucous epidermal nevusPathogenesis-directed therapyCohort of patientsErythematous scaly plaquesRare skin diseaseLines of BlaschkoSomatic pathogenic variantsNSDHL mutationsHistopathological evaluationInflammatory disordersScaly plaquesHistopathologic evaluationHistopathological criteriaLinear porokeratosisSkin lesionsAffected skinPatientsSkin diseasesClinical descriptorsHeterogenous group
2021
Pigmented demodicidosis ‐ an under‐recognized cause of facial hyperpigmentation
Feuerman H, Atzmony L, Glick M, Sherman S, Snast I, Hodak E, Segal R. Pigmented demodicidosis ‐ an under‐recognized cause of facial hyperpigmentation. International Journal Of Dermatology 2021, 61: 564-569. PMID: 34897670, DOI: 10.1111/ijd.15992.Peer-Reviewed Original ResearchConceptsFacial hyperpigmentationMedical files of patientsFiles of patientsOutpatient dermatology clinicBackground erythemaHistopathological featuresDermatology clinicMedical filesReticulate pigmentationDermoscopic findingsFollicular openingsFacial pigmentationHyperpigmentationHair folliclesSkin roughnessDemodicidosisPatientsDiagnostic dataErythemaFindingsCohortFolliclesClinicAffected areasInfiltration
2019
Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy
Atzmony L, Lim YH, Hamilton C, Leventhal JS, Wagner A, Paller AS, Choate KA. Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy. Journal Of The American Academy Of Dermatology 2019, 82: 123-131. PMID: 31449901, PMCID: PMC7039698, DOI: 10.1016/j.jaad.2019.08.043.Peer-Reviewed Original ResearchConceptsPorokeratosis lesionsPorokeratosis palmaris et plantaris disseminataPathogenesis-directed therapyTreatment of porokeratosisWeeks of therapyInitiation of therapyPathway gene mutationsDisseminated superficial actinic porokeratosisPathogenesis-based therapiesCase series designSuperficial actinic porokeratosisAdverse eventsTopical therapyTherapeutic optionsComplete clearanceLinear porokeratosisPatientsActinic porokeratosisTherapyPorokeratosisLesionsGene mutationsModerate improvementLovastatinToxic metabolites
2018
Psychological stress and psoriasis: a systematic review and meta‐analysis
Snast I, Reiter O, Atzmony L, Leshem Y, Hodak E, Mimouni D, Pavlovsky L. Psychological stress and psoriasis: a systematic review and meta‐analysis. British Journal Of Dermatology 2018, 178: e363-e363. DOI: 10.1111/bjd.16620.Peer-Reviewed Original ResearchPsychological stressStressful eventsRecalled stressful eventsLack of robust evidencePsoriasis patientsDiagnosis of stress disordersChronic inflammatory skin diseaseInfluence of psychological stressPatient recallWorsening of psoriasisInflammatory skin diseaseStress disorderPatient's memoryEvaluate disease severityRobust evidencePsoriasis onsetPsoriasis severityPsoriasisPatientsControl groupDisease severitySkin diseasesPsychological stress and psoriasis: a systematic review and meta‐analysis
Snast I, Reiter O, Atzmony L, Leshem Y, Hodak E, Mimouni D, Pavlovsky L. Psychological stress and psoriasis: a systematic review and meta‐analysis. British Journal Of Dermatology 2018, 178: 1044-1055. PMID: 29124739, DOI: 10.1111/bjd.16116.Peer-Reviewed Original ResearchConceptsCase-control studyOdds ratioPsychological stressExacerbation of psoriasisOnset of psoriasisCross-sectional studyStress disorder diagnosisStressful eventsPsoriasis exacerbationRetrospective studyCohort studySystematic reviewMeta-analysesPsoriasisCochrane LibraryMeta-analysisPatientsExacerbationDisorder diagnosisStress reactivityAssociationSurveyStress levelsPsycINFOOdds
2017
Venous thromboembolism in patients with pemphigus: A cohort study
Leshem Y, Atzmony L, Dudkiewicz I, Hodak E, Mimouni D. Venous thromboembolism in patients with pemphigus: A cohort study. Journal Of The American Academy Of Dermatology 2017, 77: 256-260. PMID: 28495498, DOI: 10.1016/j.jaad.2017.01.059.Peer-Reviewed Original ResearchConceptsVenous thromboembolism riskDevelopment of venous thromboembolismVenous thromboembolism risk factorsVenous thromboembolismCharacteristics of venous thromboembolismRisk factorsAsymptomatic venous thromboembolismDeep vein thrombosesFollow-up timeVenous thromboembolic eventsPemphigus diagnosisPemphigus treatmentPatient yearsPulmonary embolismVein thrombosesCause of deathRetrospective studyThrombo-prophylaxisHealth recordsPatientsHigh riskPemphigusDiagnosed pemphigusControl populationThromboembolism
2016
Is There a Role for Opportunistic Infection Prophylaxis in Pemphigus? An Expert Survey
Leshem Y, Snast I, Friedland R, Atzmony L, Levi A, Hodak E, Mimouni D. Is There a Role for Opportunistic Infection Prophylaxis in Pemphigus? An Expert Survey. American Journal Of Clinical Dermatology 2016, 18: 127-132. PMID: 27826815, DOI: 10.1007/s40257-016-0233-1.Peer-Reviewed Original ResearchConceptsOpportunistic infection prophylaxisImmunosuppressive therapyInfection prophylaxisInitiation of immunosuppressive therapyEffects of immunosuppressive therapyAdverse effects of immunosuppressive therapyEmergence of resistant pathogensCessation of immunosuppressionHistory of OIInfectious disease specialistsDrug of choiceTertiary care settingBackgroundOpportunistic infectionsImmunosuppressive agentsImmunosuppressive conditionsRisk stratificationDisease specialistsFrequent drugsResistant pathogensSide effectsSevere diseaseHepatitis virusObjectiveOur objectivePatientsPemphigus
2015
Erythrodermic mycosis fungoides and Sézary syndrome treated with extracorporeal photopheresis as part of a multimodality regimen: A single‐centre experience
Atzmony L, Amitay-Laish I, Gurion R, Shahal-Zimra Y, Hodak E. Erythrodermic mycosis fungoides and Sézary syndrome treated with extracorporeal photopheresis as part of a multimodality regimen: A single‐centre experience. Journal Of The European Academy Of Dermatology And Venereology 2015, 29: 2382-2389. PMID: 26299651, DOI: 10.1111/jdv.13243.Peer-Reviewed Original ResearchConceptsExtracorporeal photopheresisErythrodermic mycosis fungoidesSezary syndromeLeukaemic involvementMycosis fungoidesErythrodermic MFTreated with extracorporeal photopheresisBlood responseNarrow-band ultraviolet BSkin responsePatch-stage MFClinical response rateElectron beam radiotherapyTopical nitrogen mustardTertiary medical centreMultimodal approachBeam radiotherapyMultimodality regimenClinical responseAdjunctive therapyInterferon-aSurvival advantageMedical filesPhotopheresisPatients
2012
Symptomatic venous thromboembolism in elderly patients following major orthopedic surgery of the lower limb is associated with elevated vitamin B12 serum levels
Grossfeld A, Dekel S, Lerman Y, Sherman S, Atzmony L, Salai M, Justo D. Symptomatic venous thromboembolism in elderly patients following major orthopedic surgery of the lower limb is associated with elevated vitamin B12 serum levels. Clinical Biochemistry 2012, 46: 54-58. PMID: 23000313, DOI: 10.1016/j.clinbiochem.2012.09.011.Peer-Reviewed Original ResearchConceptsVitamin B12 serum levelsB12 serum levelsAssociated with systemic inflammationVenous thromboembolism risk factorsSymptomatic venous thromboembolismSerum levelsVenous thromboembolismElderly patientsStudy groupOrthopedic surgerySystemic inflammationControl groupCo-morbiditiesRisk factorsAssociated with venous thromboembolismPatients venous thromboembolismLower limbsRetrospective studyVTE patientsMedical chartsSurgeryPatientsIndependent of demographicsMortalityThromboembolism
2010
Thrombosis associated with acute cytomegalovirus infection: A meta-analysis
Justo D, Finn T, Atzmony L, Guy N, Steinvil A. Thrombosis associated with acute cytomegalovirus infection: A meta-analysis. European Journal Of Internal Medicine 2010, 22: 195-199. PMID: 21402253, DOI: 10.1016/j.ejim.2010.11.006.Peer-Reviewed Original ResearchConceptsAcute CMV infectionSplanchnic vein thrombosisCMV infectionImmunocompetent patientsImmunocompromised patientsVein thrombosisTreated with antiviral agentsDuration of anticoagulant therapyClinical characteristics of patientsIn-hospital mortality rateSigns of thrombosisIncidence of thrombosisCharacteristics of patientsAcute cytomegalovirusAnticoagulant therapyFemale-male ratioClinical characteristicsSplenic infarctionInherited predispositionHospitalized patientsThrombosisPatientsAntiviral agentsMedical literatureClinical experienceIncidence of Cytomegalovirus-associated thrombosis and its risk factors: A case-control study
Atzmony L, Halutz O, Avidor B, Finn T, Zimmerman O, Steinvil A, Zeltser D, Giladi M, Justo D. Incidence of Cytomegalovirus-associated thrombosis and its risk factors: A case-control study. Thrombosis Research 2010, 126: e439-e443. PMID: 20926120, DOI: 10.1016/j.thromres.2010.09.006.Peer-Reviewed Original ResearchConceptsAcute CMV infectionAssociated with thrombosisCMV infectionConsecutive patientsRisk factorsControl groupSex-matched consecutive patientsStudy groupCohort of patientsTertiary medical centerConsecutive matched patientsBinary logistic regression analysisLogistic regression analysisVenous thrombosesVenous thrombosisMatched patientsThrombosis incidenceInherited predispositionMedical chartsArterial thrombosisPhysician awarenessThrombosisAge-matchedPatientsMedical Center
2009
Inherited and acquired predispositions for thrombosis in immunocompetent patients with cytomegalovirus-associated thrombosis
Atzmony L, Grosfeld A, Saar N, Justo D. Inherited and acquired predispositions for thrombosis in immunocompetent patients with cytomegalovirus-associated thrombosis. European Journal Of Internal Medicine 2009, 21: 2-5. PMID: 20122604, DOI: 10.1016/j.ejim.2009.10.002.Peer-Reviewed Original ResearchConceptsImmunocompetent adultsInherited predispositionImmunocompetent patientsFactor V Leiden mutationV Leiden mutationThrombosis risk factorsImmunocompromised patientsInherited thrombophiliaOral contraceptivesCase seriesCase reportElderly patientsClinical circumstancesThrombosisClinical importanceRisk factorsPatientsPredispositionComplicationsCMVAdultsReportsThrombophiliaContraceptionInfantsC-reactive protein velocity following antibiotics in patients with chronic obstructive pulmonary disease exacerbation and community acquired pneumonia
Justo D, Lachmi S, Saar N, Joffe E, Atzmony L, Mashav N, Henis O, Sade B, Chundadze T, Steinvil A, Paran Y. C-reactive protein velocity following antibiotics in patients with chronic obstructive pulmonary disease exacerbation and community acquired pneumonia. European Journal Of Internal Medicine 2009, 20: 518-521. PMID: 19712857, DOI: 10.1016/j.ejim.2009.03.008.Peer-Reviewed Original ResearchConceptsCAP patientsChronic obstructive pulmonary disease exacerbationsCommunity acquired pneumoniaChronic obstructive pulmonary diseaseInitiation of antibacterial treatmentChronic obstructive pulmonary disease exacerbation patientsCRP levelsExacerbation patientsC-reactive protein velocityAntibacterial treatmentTreated with cephalosporinsChronic obstructive pulmonary disease patientsDays of hospitalizationChest X-rayInternal medicine departmentObstructive pulmonary diseaseProductive coughAntibiotic administrationDisease exacerbationStudy groupPulmonary diseaseCRPPatientsExacerbationMedicine departmentTakotsubo cardiomyopathy and QT interval prolongation: who are the patients at risk for torsades de pointes?
Samuelov-Kinori L, Kinori M, Kogan Y, Swartzon M, Shalev H, Guy D, Ferenidou F, Mashav N, Sadeh B, Atzmony L, Kliuk-Ben-Basat O, Steinvil A, Justo D. Takotsubo cardiomyopathy and QT interval prolongation: who are the patients at risk for torsades de pointes? Journal Of Electrocardiology 2009, 42: 353-357.e1. PMID: 19261294, DOI: 10.1016/j.jelectrocard.2009.01.005.Peer-Reviewed Original ResearchConceptsQT interval prolongationInterval prolongationTorsades de pointesTakotsubo cardiomyopathySystolic dysfunctionRisk factorsSuspicion of congenital long-QT syndromeFemale sexClinical circumstancesCongenital long QT syndromeMaximal troponin levelsQT-prolonging agentsLow ejection fractionLong QT syndromePeer review reportsTroponin levelsEjection fractionQT syndromeSinus rhythmAtrial fibrillationMale sexPatientsProlongationLiterature searchTakotsubo
2008
Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report
Atzmony L, Saar N, Chundadze T, Arbel Y, Justo D, Mashav N. Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report. Journal Of Medical Case Reports 2008, 2: 385. PMID: 19087249, PMCID: PMC2615038, DOI: 10.1186/1752-1947-2-385.Peer-Reviewed Original ResearchFactor V Leiden mutationV Leiden mutationSplenic infarctionAcute cytomegalovirus infectionConclusionThis case reportTrans-esophageal echocardiographySpontaneous splenic infarctionCytomegalovirus infectionImmunocompromized patientsAnticoagulant treatmentFemale patientsCase reportCaucasian womenMural thrombusPatientsMedical literatureThrombosisInfarctionCytomegalovirusMutationsEchocardiographyThrombusInfectionCases