2019
Modulatory Role of SIRT1 and Resistin as Therapeutic Targets in Patients with Aortic Valve Stenosis
Samiei N, Hosseini S, Maleki M, Moradi L, Joghataei M, Arabian M. Modulatory Role of SIRT1 and Resistin as Therapeutic Targets in Patients with Aortic Valve Stenosis. Archives Of Medical Research 2019, 50: 333-341. PMID: 31677538, DOI: 10.1016/j.arcmed.2019.10.001.Peer-Reviewed Original ResearchConceptsSilent information regulator 1Aortic valve stenosisPeripheral blood mononuclear cellsResistin levelsValve stenosisAS groupExpression of SIRT1Modulatory roleAortic valve replacementLevels of resistinBlood mononuclear cellsInformation regulator 1Effects of resveratrolAS preventionValve replacementPharmacological therapyMononuclear cellsResistin expressionSIRT1 expressionTargeted therapySIRT1 levelsTherapeutic effectHealthy subjectsNovel biomarkersTherapeutic target
2016
Epidermal growth factor receptor targeting alters gene expression and restores the adhesion function of cancerous cells as measured by single cell force spectroscopy
Azadi S, Tafazzoli-Shadpour M, Omidvar R, Moradi L, Habibi-Anbouhi M. Epidermal growth factor receptor targeting alters gene expression and restores the adhesion function of cancerous cells as measured by single cell force spectroscopy. Molecular And Cellular Biochemistry 2016, 423: 129-139. PMID: 27696309, DOI: 10.1007/s11010-016-2831-x.Peer-Reviewed Original ResearchConceptsCell-cell adhesionE-cadherin expressionEpidermal growth factor receptorGrowth factor receptorAdhesion functionCell-cell adhesion forcesCell-cell adhesion functionSingle-cell force spectroscopyFactor receptorAlters gene expressionCell force spectroscopyE-cadherin geneTime PCR analysisBlockade of EGFRTreatment of cellsForce spectroscopy techniquesHuman epithelial cancer cell linesEpithelial cancer cell linesCancerous cellsCell mechanical propertiesEGFR activityGene expressionCell behaviorInhibition of metastasisCancer progression
2008
The Study of Developmental Capacity of Vitrified Mouse Blastocysts in Different Straws after Transfer to Mouse Pseudo Pregnant
Saki G, Rahim F, Moradi L. The Study of Developmental Capacity of Vitrified Mouse Blastocysts in Different Straws after Transfer to Mouse Pseudo Pregnant. Pakistan Journal Of Biological Sciences 2008, 11: 1809-14. PMID: 18817221, DOI: 10.3923/pjbs.2008.1809.1814.Peer-Reviewed Original ResearchConceptsBirth rateConventional strawRe-expansion rateFemale NMRI micePregnant miceNMRI miceCervical dislocationUterine hornVitrification of blastocystsCPS groupSuper ovulationPregnancyMouse blastocystsPseudo-pregnant miceMiceReproductive technologiesMouse abdomenFresh blastocystsUntreated controlsDevelopmental capacityPre-implantation mammalian embryosBlastocystsM16 mediumGroupGonadotrophin