Natural biomacromolecule based composite scaffolds from silk fibroin, gelatin and chitosan toward tissue engineering applications
Asadpour S, Kargozar S, Moradi L, Ai A, Nosrati H, Ai J. Natural biomacromolecule based composite scaffolds from silk fibroin, gelatin and chitosan toward tissue engineering applications. International Journal Of Biological Macromolecules 2019, 154: 1285-1294. PMID: 31733251, DOI: 10.1016/j.ijbiomac.2019.11.003.Peer-Reviewed Original ResearchConceptsComposite scaffoldsTissue engineering applicationsSilk fibroinMechanical strengthEngineering applicationsFabricated composite scaffoldsNatural extra cellular matrixBiocompatibility of scaffoldsDifferent blending ratiosFreeze-drying techniqueSilk fibroin-chitosanGood interconnectivityTensile testsSuitable porositySurface wettabilityBlending ratioDegradation measurementsBombyx mori silkwormPore sizeChitosan-gelatinFibroinCell affinityDegradation rateExtra-cellular matrixWater uptake