Relationship between postprandial metabolomics and colon motility in children with constipation
Rodriguez L, Roberts LD, LaRosa J, Heinz N, Gerszten R, Nurko S, Goldstein AM. Relationship between postprandial metabolomics and colon motility in children with constipation. Neurogastroenterology & Motility 2013, 25: 420-e299. PMID: 23421516, PMCID: PMC3877617, DOI: 10.1111/nmo.12086.Peer-Reviewed Original ResearchConceptsTreatment of constipationColonic motilityMotility indexMotility patternsNormal postprandial increasePostprandial motility patternCohort of childrenPostprandial metabolic changesSignificant metabolite changesColon manometryColon motilityConstipated childrenProspective studyStandardized mealKynurenic acidMeal challengePostprandial increasePostprandial changesMultiple time pointsConstipationLipid metabolitesPotential metabolic targetsAbstractTextSpecific metabolitesMetabolic changes