2023
Clinical Utility of Ileal Motility in Children With Defecation Disorders and Children With Chronic Intestinal Pseudo‐Obstruction
Colliard K, Nurko S, Flores A, Rodriguez L. Clinical Utility of Ileal Motility in Children With Defecation Disorders and Children With Chronic Intestinal Pseudo‐Obstruction. Journal Of Pediatric Gastroenterology And Nutrition 2023, 77: 327-331. PMID: 37229777, DOI: 10.1097/mpg.0000000000003841.Peer-Reviewed Original ResearchConceptsAntroduodenal manometryDefecation disordersPostprandial responseGroup BChronic Intestinal Pseudo-ObstructionIntestinal Pseudo-ObstructionNormal postprandial responseModerate agreementSmall bowel motilityLogistic regression analysisOstomy closurePseudo-ObstructionBowel motilityRetrospective reviewIleal motilityIndication groupGroup AClinical utilityYounger agePatientsMotility patternsPhase IIIMotor complexDisordersManometry
2013
Relationship between postprandial metabolomics and colon motility in children with constipation
Rodriguez L, Roberts LD, LaRosa J, Heinz N, Gerszten R, Nurko S, Goldstein AM. Relationship between postprandial metabolomics and colon motility in children with constipation. Neurogastroenterology & Motility 2013, 25: 420-e299. PMID: 23421516, PMCID: PMC3877617, DOI: 10.1111/nmo.12086.Peer-Reviewed Original ResearchConceptsTreatment of constipationColonic motilityMotility indexMotility patternsNormal postprandial increasePostprandial motility patternCohort of childrenPostprandial metabolic changesSignificant metabolite changesColon manometryColon motilityConstipated childrenProspective studyStandardized mealKynurenic acidMeal challengePostprandial increasePostprandial changesMultiple time pointsConstipationLipid metabolitesPotential metabolic targetsAbstractTextSpecific metabolitesMetabolic changes