2024
Testing in functional constipation—What's new and what works
Rodriguez L. Testing in functional constipation—What's new and what works. Alimentary Pharmacology & Therapeutics 2024, 60: s30-s41. PMID: 38940015, DOI: 10.1111/apt.17857.Peer-Reviewed Original ResearchColonic manometryFecal incontinenceConventional therapyRadiopaque markersFunctional constipationNon-retentive fecal incontinenceDiagnostic studiesFailed medical therapyLumbar spine MRIRecto-anal inhibitory reflexAnal resting pressureAbdominal X-raySpine MRIAnorectal manometryMedical therapyPaediatric constipationSurgical interventionClinical findingsInhibitory reflexEvaluate anatomySpinal abnormalitiesColonic transitMedical historyPaediatric gastroenterologistsConstipation
2012
Endoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study
Rodriguez L, Rosen R, Manfredi M, Nurko S. Endoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study. Gastrointestinal Endoscopy 2012, 75: 302-309. PMID: 22248598, PMCID: PMC3260460, DOI: 10.1016/j.gie.2011.09.042.Peer-Reviewed Original ResearchConceptsOpen-label studyBotulinum toxin APredictive factorsToxin ASingle tertiary care centerLong-term clinical outcomesRefractory gastroparesis symptomsSymptoms of gastroparesisPlacebo-controlled trialTertiary care centerManagement of childrenSingle case reportsTreatment of childrenGastroparesis refractoryGastroparesis symptomsIntrapyloric injectionReported exacerbationsSpastic disordersClinical improvementMedian durationOlder patientsBotulinum injectionMale patientsMedical therapyRetrospective review
2010
Antegrade colonic enemas and intestinal diversion are highly effective in the management of children with intractable constipation
Christison-Lagay ER, Rodriguez L, Kurtz M, St. Pierre K, Doody DP, Goldstein AM. Antegrade colonic enemas and intestinal diversion are highly effective in the management of children with intractable constipation. Journal Of Pediatric Surgery 2010, 45: 213-219. PMID: 20105606, DOI: 10.1016/j.jpedsurg.2009.10.034.Peer-Reviewed Original ResearchConceptsAntegrade continence enemaIntractable constipationSatisfactory outcomeContinence enemaIntestinal continuityRetrospective reviewSurgical approachPredictors of successColonic manometry studiesPassage of stoolPrimary colonic resectionManagement of childrenOptimal surgical approachAntegrade colonic enemaInitial therapyAbdominal distensionIdiopathic constipationPrimary resectionColonic resectionAdditional surgeryColonic manometryMedical therapyPediatric patientsACE procedureColonic enema