2005
Isotretinoin does have an adverse effect on bone mineral density
Milstone LM, Insogna KL, Leachman SA. Isotretinoin does have an adverse effect on bone mineral density. Journal Of The American Academy Of Dermatology 2005, 53: 181. PMID: 15965453, DOI: 10.1016/j.jaad.2005.03.025.Commentaries, Editorials and Letters
2002
Is retinoid-induced osteopenia reversible?
Milstone AM, Milstone LM. Is retinoid-induced osteopenia reversible? JAMA Dermatology 2002, 138: 1516-7. PMID: 12437467, DOI: 10.1001/archderm.138.11.1516-a.Commentaries, Editorials and Letters
1999
Bone Densities in Patients Receiving Isotretinoin for Cystic Acne
Leachman SA, Insogna KL, Katz L, Ellison A, Milstone LM. Bone Densities in Patients Receiving Isotretinoin for Cystic Acne. JAMA Dermatology 1999, 135: 961-965. PMID: 10456346, DOI: 10.1001/archderm.135.8.961.Peer-Reviewed Original ResearchConceptsCystic acneBone densityWard's triangleCalcium metabolismHealthy control subjectsYoung menIsotretinoin useOral isotretinoinPatient groupControl subjectsMean changeHealthy volunteersControl groupAcnePatientsMeasurable alterationsIsotretinoinFurther studiesOsteoporosisDecreased densityRetinoidsMetabolismMenBoneDirect effect