2015
The Protein Acyl Transferase ZDHHC21 Modulates &agr;1 Adrenergic Receptor Function and Regulates Hemodynamics
Marin EP, Jozsef L, Di Lorenzo A, Held KF, Luciano AK, Melendez J, Milstone LM, Velazquez H, Sessa WC. The Protein Acyl Transferase ZDHHC21 Modulates &agr;1 Adrenergic Receptor Function and Regulates Hemodynamics. Arteriosclerosis Thrombosis And Vascular Biology 2015, 36: 370-379. PMID: 26715683, PMCID: PMC4984414, DOI: 10.1161/atvbaha.115.306942.Peer-Reviewed Original ResearchMeSH KeywordsAcyltransferasesAdrenergic alpha-1 Receptor AgonistsAnimalsAortaBlood PressureDose-Response Relationship, DrugEpinephrineFibroblastsGenotypeHeart RateHEK293 CellsHemodynamicsHumansHypotensionLipoylationMesenteric ArteriesMice, Inbred C57BLMice, Mutant StrainsMutationNorepinephrinePhenotypePhenylephrineReceptors, Adrenergic, alpha-1Signal TransductionTachycardiaTime FactorsTransfectionVasoconstrictionConceptsProtein acyl transferasesNovel molecular modeZDHHC familyLipid palmitateZDHHC enzymesVascular toneNumerous proteinsPossible molecular mechanismsProtein localizationAdrenergic receptor gene expressionGene expressionMolecular mechanismsVascular functionBiochemical studiesReceptor gene expressionAcyl transferaseMolecular modePalmitoylationΑ1-adrenergic receptor agonistTelemetry studiesInfusion of phenylephrinePhysiological studiesΑ1-adrenergic receptorsReceptor functionAdrenergic receptor agonist
1985
Heterogeneity of Basal Keratinocytes: Nonrandom Distribution of Thymidine-Labeled Basal Cells in Confluent Cultures Is Not a Technical Artifact
Milstone L, LaVigne J. Heterogeneity of Basal Keratinocytes: Nonrandom Distribution of Thymidine-Labeled Basal Cells in Confluent Cultures Is Not a Technical Artifact. Journal Of Investigative Dermatology 1985, 84: 504-507. PMID: 3998498, DOI: 10.1111/1523-1747.ep12273479.Peer-Reviewed Original Research
1984
2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Hyperplasia in Confluent Cultures of Human Keratinocytes
Milstone L, LaVigne J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Hyperplasia in Confluent Cultures of Human Keratinocytes. Journal Of Investigative Dermatology 1984, 82: 532-534. PMID: 6210328, DOI: 10.1111/1523-1747.ep12261149.Peer-Reviewed Original Research
1982
Retinoic Acid Causes Premature Desquamation of Cells from Confluent Cultures of Stratified Squamous Epithelia
Milstone L, McGuire J, Lavigne J. Retinoic Acid Causes Premature Desquamation of Cells from Confluent Cultures of Stratified Squamous Epithelia. Journal Of Investigative Dermatology 1982, 79: 253-260. PMID: 7130743, DOI: 10.1111/1523-1747.ep12500073.Peer-Reviewed Original Research
1980
Keratins in Cultivated Human Keratinocytes Are Stable*
McGuire J, Milstone L, Osber M, Ingalls L. Keratins in Cultivated Human Keratinocytes Are Stable*. Current Problems In Dermatology 1980, 10: 327-342. PMID: 6165526, DOI: 10.1159/000396299.Peer-Reviewed Original Research