2022
Association Between Endovascular Therapy Time to Treatment and Outcomes in Patients With Basilar Artery Occlusion
Joundi R, Sun J, Xian Y, Alhanti B, Nogueira R, Bhatt D, Fonarow G, Saver J, Schwamm L, Smith E. Association Between Endovascular Therapy Time to Treatment and Outcomes in Patients With Basilar Artery Occlusion. Circulation 2022, 145: 896-905. PMID: 35050693, DOI: 10.1161/circulationaha.121.056554.Peer-Reviewed Original ResearchConceptsBasilar artery occlusionSymptomatic intracranial hemorrhageEndovascular therapySymptom onsetEVT timesHospital mortalityArtery occlusionMedian onsetIntracranial hemorrhageBetter outcomesHealth Stroke Scale scoreIndividual-level patient dataMedian National InstitutesStroke Scale scoreHospital-level factorsProportion of patientsLogistic regression modelsSubstantial reperfusionAnterior circulationPrimary outcomeUS registryMean ageDevastating conditionImproved outcomesTherapy time
2005
Hypoattenuation on CT angiographic source images predicts risk of intracerebral hemorrhage and outcome after intra-arterial reperfusion therapy.
Schwamm L, Rosenthal E, Swap C, Rosand J, Rordorf G, Buonanno F, Vangel M, Koroshetz W, Lev M. Hypoattenuation on CT angiographic source images predicts risk of intracerebral hemorrhage and outcome after intra-arterial reperfusion therapy. American Journal Of Neuroradiology 2005, 26: 1798-803. PMID: 16091532, PMCID: PMC7975152.Peer-Reviewed Original ResearchMeSH KeywordsAgedArterial Occlusive DiseasesBasilar ArteryCerebral AngiographyCerebral HemorrhageCerebral InfarctionFemaleFibrinolytic AgentsHematomaHumansMaleMiddle AgedMiddle Cerebral ArteryPredictive Value of TestsRetrospective StudiesRisk AssessmentTissue Plasminogen ActivatorTomography, X-Ray ComputedConceptsIntra-arterial reperfusion therapyHemorrhagic transformationPoor clinical outcomeCTA source imagesReperfusion therapyClinical outcomesCT angiographic source imagesCatheter-based reperfusionReal-time risk stratificationSymptomatic hemorrhagic transformationReceiver operator characteristic curveBlood glucose levelsOperator characteristic curveAxial source imagesNormal contralateral tissueConsecutive patientsVascular insufficiencyIntracerebral hemorrhageRisk stratificationStroke patientsPoor outcomeSignificant complicationsRisk factorsContralateral tissueLesion volume