2017
Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke
Yaghi S, Willey JZ, Cucchiara B, Goldstein JN, Gonzales NR, Khatri P, Kim LJ, Mayer SA, Sheth KN, Schwamm LH. Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke. Stroke 2017, 48: e343-e361. PMID: 29097489, DOI: 10.1161/str.0000000000000152.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageAcute ischemic strokeIschemic strokeSystemic thrombolysisCase seriesIntravenous thrombolytic therapyMainstay of treatmentSmall case seriesTreatment of patientsBlood-brain barrierWriting group membersHemorrhagic transformationIntravenous alteplaseFeared complicationSevere complicationsPrompt diagnosisRandomized trialsThrombolytic therapyIntracranial hemorrhageRetrospective studyRisk factorsEarly correctionAlteplaseStrokeLiterature review
2013
Factors Influencing the Decline in Stroke Mortality
Lackland DT, Roccella EJ, Deutsch AF, Fornage M, George MG, Howard G, Kissela BM, Kittner SJ, Lichtman JH, Lisabeth LD, Schwamm LH, Smith EE, Towfighi A. Factors Influencing the Decline in Stroke Mortality. Stroke 2013, 45: 315-353. PMID: 24309587, PMCID: PMC5995123, DOI: 10.1161/01.str.0000437068.30550.cf.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAir PollutionAmerican Heart AssociationAspirinAssociationAtrial FibrillationBlood PressureClinical Trials as TopicDiabetes MellitusExerciseFemaleHeart DiseasesHumansHyperlipidemiasHypertensionIncidenceInternational Classification of DiseasesMaleMiddle AgedObesityObservational Studies as TopicPlatelet Aggregation InhibitorsPopulationPrevalenceSecondary PreventionSex FactorsSmokingStrokeThrombolytic TherapyUnited StatesYoung AdultConceptsStroke mortalityCause of deathStroke riskAmerican Heart Association Stroke Council's Scientific Statement Oversight CommitteeAmerican Heart Association's Manuscript Oversight CommitteeAmerican Heart Association Science AdvisoryScientific Statements Oversight Committee reviewStroke Council Leadership reviewLower case fatality rateEvidence-based public health programsMajor public health burdenControl of hypertensionChronic lung diseaseFourth leading causeCase fatality rateTreatment of hypertensionPublic health burdenWriting group membersAttributable risk estimatesPublic health guidelinesYears of ageMajor public healthPublic health programsCombination of interventionsDyslipidemia control