2006
First-pass quantitative CT perfusion identifies thresholds for salvageable penumbra in acute stroke patients treated with intra-arterial therapy.
Schaefer P, Roccatagliata L, Ledezma C, Hoh B, Schwamm L, Koroshetz W, Gonzalez R, Lev M. First-pass quantitative CT perfusion identifies thresholds for salvageable penumbra in acute stroke patients treated with intra-arterial therapy. American Journal Of Neuroradiology 2006, 27: 20-5. PMID: 16418350, PMCID: PMC7976067.Peer-Reviewed Original ResearchConceptsCerebral blood volumeAcute stroke patientsCT perfusionStroke patientsCBF ratioGray matterWhite matterAbsolute cerebral blood volumeCBV ratioIntra-arterial therapyIschemic brain tissueQuantitative CT perfusionDynamic CT perfusionIA therapyRecanalization therapyStroke onsetSalvageable penumbraInfarct coreIschemic tissueUninvolved regionsIschemic regionBlood volumeCBF valuesPatientsBrain tissue
2004
Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury.
Huisman T, Schwamm L, Schaefer P, Koroshetz W, Shetty-Alva N, Ozsunar Y, Wu O, Sorensen A. Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury. American Journal Of Neuroradiology 2004, 25: 370-6. PMID: 15037457, PMCID: PMC8158566.Peer-Reviewed Original ResearchConceptsGlasgow Coma ScaleDiffusion tensor imagingTraumatic brain injuryRankin scoreInternal capsuleApparent diffusion coefficientADC valuesFA valuesWhite matter injuryHealthy control subjectsDiffuse axonal injuryCorresponding ADC valuesFractional anisotropy valuesNew MR imaging techniquesTBI correlatesComa ScaleClinical scoresAxonal injuryControl subjectsBrain injuryClinical markersMR imaging techniquesTissue injuryBrain ultrastructureWhite matter
2001
Frequency and Clinical Context of Decreased Apparent Diffusion Coefficient Reversal in the Human Brain
Grant P, He J, Halpern E, Wu O, Schaefer P, Schwamm L, Budzik R, Sorensen A, Koroshetz W, Gonzalez R. Frequency and Clinical Context of Decreased Apparent Diffusion Coefficient Reversal in the Human Brain. Radiology 2001, 221: 43-50. PMID: 11568319, DOI: 10.1148/radiol.2211001523.Peer-Reviewed Original ResearchConceptsImaging studiesClinical settingVenous sinus thrombosisMagnetic resonance imaging studyOnset of symptomsMR imaging findingsComplicated clinical settingsMR imaging studiesMR imaging examinationsResonance imaging studyGray matter regionsADC lesionsArterial infarctionPersistent symptomsSinus thrombosisClinical outcomesImaging findingsClinical historyImaging examinationsADC decreaseSame periodWhite matterGray matterMatter regionsT2 changes
1998
Assessment of cerebral perfusion and arterial anatomy in hyperacute stroke with three-dimensional functional CT: early clinical results.
Hunter G, Hamberg L, Ponzo J, Huang-Hellinger F, Morris P, Rabinov J, Farkas J, Lev M, Schaefer P, Ogilvy C, Schwamm L, Buonanno F, Koroshetz W, Wolf G, González R. Assessment of cerebral perfusion and arterial anatomy in hyperacute stroke with three-dimensional functional CT: early clinical results. American Journal Of Neuroradiology 1998, 19: 29-37. PMID: 9432154, PMCID: PMC8337333.Peer-Reviewed Original ResearchConceptsHyperacute strokeFunctional CTIschemic changesEarly clinical resultsCerebral blood volumeContrast-enhanced scansHelical CT techniqueOcclusion of vesselsHyperacute groupCerebral perfusionPBV mapsArterial anatomyPatient populationBrain stemClinical resultsCT angiogramContrast administrationRegional perfusionCT angiographyBlood volumePatientsPBV valuesWhite matterGray matterClinical feasibility