2021
Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-19 experience
Lee E, Selig W, Meehan C, Bacha J, Barone A, Bloomquist E, Chang S, de Groot J, Galanis E, Hassan I, Kalidas C, Khasraw M, Kvedar J, Lassman A, Puduvalli V, Sahebjam S, Schwamm L, Tamir S, Welch M, Yung W, Zadeh G, Arons D, Wen P. Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-19 experience. Neuro-Oncology 2021, 23: 1252-1260. PMID: 33822177, PMCID: PMC8083574, DOI: 10.1093/neuonc/noab082.Peer-Reviewed Original ResearchConceptsTumor clinical trialsBrain tumor clinical trialsClinical trialsNational Brain Tumor SocietyCOVID-19 experienceClinical trial designUse of telemedicineNational Cancer InstituteCommunity cliniciansBrain tumor communityNeuro-oncologyTrial designCancer InstituteUS FoodDrug AdministrationPatient advocatesClinical research organizationsTrialsCOVID-19Potential long-term impactLong-term impactReportPatientsCliniciansAdministration
2016
Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials
Warach S, Luby M, Albers G, Bammer R, Bivard A, Campbell B, Derdeyn C, Heit J, Khatri P, Lansberg M, Liebeskind D, Majoie C, Marks M, Menon B, Muir K, Parsons M, Vagal A, Yoo A, Alexandrov A, Baron J, Fiorella D, Furlan A, Puig J, Schellinger P, Wintermark M, Ansari S, Aviv R, Barreto A, Broderick J, Christensen S, Davis S, Demchuk A, Dippel D, Donnan G, Fiebach J, Fiehler J, Houser G, Grotta J, Hacke W, Hill M, Hsia A, Jovin T, Köhrmann M, Latour L, Leigh R, Lees K, Lev M, Marshall R, Mocco J, Nadareishvili Z, Nogueira R, Olivot J, Palesch Y, Pedraza S, Sasaki M, Saver J, Savitz S, Schwamm L, Simpkins A, Smith W, Thijs V, Thomalla G, Wechsler L, Wu O, Zaharchuk G, Zaidat O. Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials. Stroke 2016, 47: 1389-1398. PMID: 27073243, PMCID: PMC6058693, DOI: 10.1161/strokeaha.115.012364.Peer-Reviewed Original ResearchConceptsClinical trialsEndovascular trialsImaging Working GroupFinal infarct volumeLarge vessel occlusionProspective clinical trialsImaging sessionAmerican SocietyOptimal imaging methodInfarct volumeStroke neurologistsEndovascular treatmentPooled analysisTherapy clinical trialsVessel occlusionImaging selectionGood collateralsNeurovascular imagingConsensus recommendationsUS FoodDrug AdministrationNeurological disordersPooled dataTrialsNational Institute
2009
Endovascular Approaches to Acute Stroke, Part 1: Drugs, Devices, and Data
Nogueira R, Schwamm L, Hirsch J. Endovascular Approaches to Acute Stroke, Part 1: Drugs, Devices, and Data. American Journal Of Neuroradiology 2009, 30: 649-661. PMID: 19279271, PMCID: PMC7051752, DOI: 10.3174/ajnr.a1486.Peer-Reviewed Original ResearchConceptsRecombinant tissue plasminogen activatorIntravenous recombinant tissue plasminogen activatorLonger treatment windowsAcute stroke treatmentHigher recanalization ratesTissue plasminogen activatorPublic health concernMechanical revascularizationAcute strokeReperfusion techniquesEndovascular therapyStroke treatmentEndovascular approachRecanalization ratePharmacologic strategiesTreatment windowUS FoodDrug AdministrationWire disruptionTheoretic advantagesPreclinical trialsHealth concernPlasminogen activatorTherapyStroke