2018
International Comparison of Patient Characteristics and Quality of Care for Ischemic Stroke: Analysis of the China National Stroke Registry and the American Heart Association Get With The Guidelines––Stroke Program
Wangqin R, Laskowitz D, Wang Y, Li Z, Wang Y, Liu L, Liang L, Matsouaka R, Saver J, Fonarow G, Bhatt D, Smith E, Schwamm L, Bettger J, Hernandez A, Peterson E, Xian Y. International Comparison of Patient Characteristics and Quality of Care for Ischemic Stroke: Analysis of the China National Stroke Registry and the American Heart Association Get With The Guidelines––Stroke Program. Journal Of The American Heart Association 2018, 7: e010623. PMID: 30371291, PMCID: PMC6474951, DOI: 10.1161/jaha.118.010623.Peer-Reviewed Original ResearchConceptsChina National Stroke RegistryNational Stroke RegistryAcute ischemic strokeStroke RegistryIschemic strokeChinese patientsDeep venous thrombosis prophylaxisHealth Stroke ScaleVenous thrombosis prophylaxisAcute stroke careAdministration of thrombolyticsEvidence-based guidelinesAmerican Heart AssociationQuality of careBackground AdherenceDischarge antithromboticsThrombosis prophylaxisCessation counselingStroke ProgramStroke ScaleClinical characteristicsHospital arrivalNeedle timePatient characteristicsSecondary prevention
2014
Racial/Ethnic Differences in Process of Care and Outcomes Among Patients Hospitalized With Intracerebral Hemorrhage
Xian Y, Holloway R, Smith E, Schwamm L, Reeves M, Bhatt D, Schulte P, Cox M, Olson D, Hernandez A, Lytle B, Anstrom K, Fonarow G, Peterson E. Racial/Ethnic Differences in Process of Care and Outcomes Among Patients Hospitalized With Intracerebral Hemorrhage. Stroke 2014, 45: 3243-3250. PMID: 25213344, DOI: 10.1161/strokeaha.114.005620.Peer-Reviewed Original ResearchConceptsWhite patientsAsian patientsRace/ethnicityCessation counselingLower oddsDeep venous thrombosis prophylaxisGuidelines-Stroke hospitalsStroke performance measuresVenous thrombosis prophylaxisHospital-level characteristicsMultivariable logistic regressionProcess of careEthnic differencesHospital mortalityThrombosis prophylaxisCause mortalityHospital outcomesSevere strokeDysphagia screeningBlack patientsIntracerebral hemorrhageMedian lengthHigher oddsStroke educationComfort measuresHospitalized Hemorrhagic Stroke Patients with Renal Insufficiency: Clinical Characteristics, Care Patterns, and Outcomes
Ovbiagele B, Schwamm L, Smith E, Grau-Sepulveda M, Saver J, Bhatt D, Hernandez A, Peterson E, Fonarow G. Hospitalized Hemorrhagic Stroke Patients with Renal Insufficiency: Clinical Characteristics, Care Patterns, and Outcomes. Journal Of Stroke And Cerebrovascular Diseases 2014, 23: 2265-2273. PMID: 25158677, DOI: 10.1016/j.jstrokecerebrovasdis.2014.04.016.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseNormal renal functionICH patientsClinical characteristicsRenal functionKidney diseaseCare patternsDeep venous thrombosis prophylaxisGuidelines-Stroke programGWTG-Stroke programVenous thrombosis prophylaxisThird of patientsGlomerular filtration rateHemorrhagic stroke patientsNormal kidney functionIntracerebral hemorrhage patientsSmoking cessation interventionHospital mortalityThrombosis prophylaxisHospital outcomesRenal dysfunctionRenal insufficiencyInpatient mortalityClinical outcomesComorbid conditions
2013
Paradoxical Association of Smoking With In‐Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke
Ali S, Smith E, Bhatt D, Fonarow G, Schwamm L. Paradoxical Association of Smoking With In‐Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke. Journal Of The American Heart Association 2013, 2: e000171. PMID: 23782919, PMCID: PMC3698779, DOI: 10.1161/jaha.113.000171.Peer-Reviewed Original ResearchConceptsNIH Stroke ScaleTissue plasminogen activatorAcute ischemic strokeIschemic strokeInpatient mortalityAtrial fibrillationMyocardial ischemiaDeep vein thrombosis prophylaxisGuidelines-Stroke registryLower inpatient mortalityOverall inpatient mortalityStroke risk factorsIn-Hospital MortalityIschemic stroke patientsCoronary artery diseaseCerebrovascular vasoreactivityEarly antithromboticsHospital mortalityThrombosis prophylaxisStroke ScaleArtery diseaseDiabetes mellitusOral intakeMultivariable analysisStroke patients
2012
Regional Variation in Recommended Treatments for Ischemic Stroke and TIA
Allen NB, Kaltenbach L, Goldstein LB, Olson DM, Smith EE, Peterson ED, Schwamm L, Lichtman JH. Regional Variation in Recommended Treatments for Ischemic Stroke and TIA. Stroke 2012, 43: 1858-1864. PMID: 22588262, DOI: 10.1161/strokeaha.112.652305.Peer-Reviewed Original ResearchConceptsDefect-free careLipid-lowering medicationsTissue-type plasminogen activatorLower oddsIschemic strokeIntravenous tissue-type plasminogen activatorSecondary stroke prevention treatmentDeep vein thrombosis prophylaxisTissue-type plasminogen activator administrationNational quality improvement programPlasminogen activatorGuideline-recommended treatmentGuidelines-Stroke hospitalsTransient ischemic attackQuarter of patientsStroke prevention treatmentBetter patient outcomesWeight loss educationQuality Improvement ProgramEligible patientsIschemic attackThrombosis prophylaxisPatient demographicsStroke treatmentMedical historyData quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit
Xian Y, Fonarow G, Reeves M, Webb L, Blevins J, Demyanenko V, Zhao X, Olson D, Hernandez A, Peterson E, Schwamm L, Smith E. Data quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit. American Heart Journal 2012, 163: 392-398.e1. PMID: 22424009, DOI: 10.1016/j.ahj.2011.12.012.Peer-Reviewed Original ResearchConceptsMedical recordsDeep venous thrombosis prophylaxisPrimary stroke center certificationGWTG-Stroke hospitalsHospital academic statusStroke center certificationVenous thrombosis prophylaxisNational Stroke RegistryAmerican Heart AssociationQuality Improvement ProgramIntraclass correlationIschemic stroke volumeGuidelines-StrokeGWTG-StrokeStroke RegistryThrombosis prophylaxisNeedle timeSerum creatinineSymptom onsetHeart AssociationCenter certificationStroke volumeRegistry dataRegistry participationCategorical variablesGet With The Guidelines Stroke Performance Indicators in a Brazilian Tertiary Hospital
de Carvalho F, Schwamm L, Kuster G, Alves M, Neto M, Silva G. Get With The Guidelines Stroke Performance Indicators in a Brazilian Tertiary Hospital. Cerebrovascular Diseases Extra 2012, 2: 26-35. PMID: 22811686, PMCID: PMC3398824, DOI: 10.1159/000339578.Peer-Reviewed Original ResearchDeep vein thrombosis prophylaxisGWTG-Stroke programEligible patientsBrazilian tertiary hospitalThrombosis prophylaxisAntithrombotic medicationStroke ProgramSymptom onsetTertiary hospitalAtrial fibrillationSmoking cessationDischarge useNational Cholesterol Education Program Adult Treatment Panel III guidelinesAmerican Heart Association/American Stroke AssociationAdult Treatment Panel III guidelinesAdult long-term disabilityTissue plasminogen activator useAntithrombotic medication useNCEP III guidelinesStroke quality improvementTransient ischemic attackAcute ischemic strokeAmerican Stroke AssociationClinical practice guidelinesLong-term disability
2011
Are Quality Improvements in the Get With The Guidelines-Stroke Program Related to Better Care or Better Data Documentation?
Reeves M, Grau-Sepulveda M, Fonarow G, Olson D, Smith E, Schwamm L. Are Quality Improvements in the Get With The Guidelines-Stroke Program Related to Better Care or Better Data Documentation? Circulation Cardiovascular Quality And Outcomes 2011, 4: 503-511. PMID: 21828344, DOI: 10.1161/circoutcomes.111.961755.Peer-Reviewed Original ResearchConceptsGuidelines-Stroke programAtrial fibrillation/flutterIntravenous recombinant tissue plasminogen activator (rt-PA) therapyRecombinant tissue plasminogen activator therapyDeep vein thrombosis prophylaxisTissue plasminogen activator therapyBetter careTarget populationGWTG-Stroke hospitalsIschemic stroke admissionsPlasminogen activator therapyNumber of patientsProportion of subjectsData collection formDischarge antithromboticsEarly antithromboticsThrombosis prophylaxisTreatment contraindicationsEligible subjectsStroke admissionsActivator therapySmoking cessationLipid therapyMeasure complianceContraindications
2010
Development of Stroke Performance Measures
Reeves M, Parker C, Fonarow G, Smith E, Schwamm L. Development of Stroke Performance Measures. Stroke 2010, 41: 1573-1578. PMID: 20489174, DOI: 10.1161/strokeaha.109.577171.Peer-Reviewed Original ResearchConceptsStroke performance measuresStroke careStroke measuresHospital-based stroke careProcess-based performance measuresDeep vein thrombosis prophylaxisStroke quality improvementStroke unit carePatient-oriented outcomesQuality of careQuality Improvement ProgramIntravenous thrombolysisThrombosis prophylaxisAcute strokeIschemic strokeUnit careDysphagia screeningFunctional recoveryPatient outcomesInpatient careCardiovascular diseaseStroke educationLiterature searchCareStrokeRace/Ethnicity, Quality of Care, and Outcomes in Ischemic Stroke
Schwamm L, Reeves M, Pan W, Smith E, Frankel M, Olson D, Zhao X, Peterson E, Fonarow G. Race/Ethnicity, Quality of Care, and Outcomes in Ischemic Stroke. Circulation 2010, 121: 1492-1501. PMID: 20308617, DOI: 10.1161/circulationaha.109.881490.Peer-Reviewed Original ResearchConceptsQuality of careWhite patientsRace/ethnicityHospital mortalityIschemic strokeHispanic patientsBlack patientsDeep vein thrombosis prophylaxisEvidence-based care processesGuidelines-Stroke programStroke performance measuresHospital-level variablesQuality Improvement ProgramRace/ethnicity groupsDischarge antithromboticsIntravenous thrombolysisRecurrent strokeThrombosis prophylaxisDiabetes mellitusStroke careAtrial fibrillationMedian lengthSmoking cessationLipid therapyHigher odds
2008
Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack
Schwamm L, Fonarow G, Reeves M, Pan W, Frankel M, Smith E, Ellrodt G, Cannon C, Liang L, Peterson E, LaBresh K. Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack. Circulation 2008, 119: 107-115. PMID: 19075103, DOI: 10.1161/circulationaha.108.783688.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute DiseaseAgedAged, 80 and overEvidence-Based MedicineFemaleGuideline AdherenceHospitalizationHospitals, CommunityHumansIschemic Attack, TransientLogistic ModelsMaleMiddle AgedMultivariate AnalysisProspective StudiesQuality of Health CareRisk FactorsStrokeThrombolytic TherapyConceptsTransient ischemic attackGuidelines-StrokeIschemic attackDeep vein thrombosis prophylaxisNational quality improvement programStroke performance measuresTreatment of strokeEvidence-based guidelinesMain outcome measuresLow-density lipoproteinQuality Improvement ProgramComposite measureDischarge antithromboticsEarly antithromboticsThrombosis prophylaxisIntravenous thrombolyticsAcute strokeIschemic strokeGuideline recommendationsStroke careAtrial fibrillationLipid treatmentCommunity hospitalOutcome measuresSustained improvement