2023
SMS-text messaging for collecting outcome measures after acute stroke
DiCarlo J, Erler K, Petrilli M, Emerson K, Gochyyev P, Schwamm L, Lin D. SMS-text messaging for collecting outcome measures after acute stroke. Frontiers In Digital Health 2023, 5: 1043806. PMID: 36910572, PMCID: PMC9996089, DOI: 10.3389/fdgth.2023.1043806.Peer-Reviewed Original ResearchModified Rankin ScaleAcute strokeOutcomes Measurement Information System (PROMIS) Global-10Acute stroke treatmentText messaging programsNIH Stroke ScaleOutcome data collectionHospitalization dischargeSMS text messagingHospital stayStroke ScaleMRS scoreRankin ScaleStroke treatmentFunctional outcomePROM scoresOutcome measuresWeighted Cohen's kappaPatientsSignificant associationStrokeTraditional followSMS textOutcomesParticipant satisfaction
2020
Prehospital Stroke Care and Regionalized Stroke Systems
Zachrison K, Schwamm L. Prehospital Stroke Care and Regionalized Stroke Systems. 2020, 35-58. DOI: 10.1017/9781316286234.004.Peer-Reviewed Original ResearchPrehospital stroke careStroke careStroke systemsAcute stroke treatmentPrevention of strokeEndovascular reperfusion therapyCause of disabilityMagnetic brain stimulationCause of deathReperfusion therapyStroke preventionStroke treatmentSurgical treatmentStroke patientsStroke recoveryBrain stimulationReview GroupAppropriate interventionsOptimal evidenceTherapeutic topicsStrokeCliniciansTreatmentCarePrevention
2018
Protocols for Endovascular Stroke Treatment Diminish the Weekend Effect Through Improvements in Off-Hours Care
Raymond S, Akbik F, Stapleton C, Mehta B, Chandra R, Gonzalez R, Rabinov J, Schwamm L, Patel A, Hirsch J, Leslie-Mazwi T. Protocols for Endovascular Stroke Treatment Diminish the Weekend Effect Through Improvements in Off-Hours Care. Frontiers In Neurology 2018, 9: 1106. PMID: 30619062, PMCID: PMC6305592, DOI: 10.3389/fneur.2018.01106.Peer-Reviewed Original ResearchTime of presentationTreatment latencyTreatment intervalEndovascular stroke treatmentProspective observational cohortOff-hour careAcute strokeMedian doorObservational cohortConsecutive patientsEndovascular therapyStroke treatmentStroke carePuncture timeFunctional outcomeProtocol adherenceThrombolysis candidatesInstitutional protocolPatient outcomesWeekend effectProtocol experienceStudy periodOutcomesPatientsRegular work hours
2017
Healthcare Resource Availability, Quality of Care, and Acute Ischemic Stroke Outcomes
O'Brien E, Wu J, Zhao X, Schulte P, Fonarow G, Hernandez A, Schwamm L, Peterson E, Bhatt D, Smith E. Healthcare Resource Availability, Quality of Care, and Acute Ischemic Stroke Outcomes. Journal Of The American Heart Association 2017, 6: e003813. PMID: 28159820, PMCID: PMC5523738, DOI: 10.1161/jaha.116.003813.Peer-Reviewed Original ResearchConceptsHealthcare resource availabilityHospital referral regionsQuality of careReferral regionsHealthcare resourcesAcute ischemic stroke outcomesAcute ischemic stroke treatmentGuidelines-Stroke hospitalsIschemic stroke outcomeIschemic stroke patientsIschemic stroke treatmentMultivariable logistic regressionLength of stayHospital-based resourcesGuidelines-StrokeHospital mortalityHospital outcomesStroke outcomeStroke careStroke treatmentStroke patientsCare resourcesHealth care dataHospital qualityStroke quality
2016
Endovascular Stroke Treatment Outcomes After Patient Selection Based on Magnetic Resonance Imaging and Clinical Criteria
Leslie-Mazwi TM, Hirsch JA, Falcone GJ, Schaefer PW, Lev MH, Rabinov JD, Rost NS, Schwamm L, González RG. Endovascular Stroke Treatment Outcomes After Patient Selection Based on Magnetic Resonance Imaging and Clinical Criteria. JAMA Neurology 2016, 73: 1-7. PMID: 26524074, DOI: 10.1001/jamaneurol.2015.3000.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingSelection of patientsClinical criteriaFavorable outcomeSuccessful reperfusionMRS scoreLTB patientsIschemic strokeTerminal internal carotid artery occlusionResonance imagingInternal carotid artery occlusionStroke treatment outcomesEndovascular stroke treatmentAcute ischemic strokeCarotid artery occlusionProspective cohort studyMiddle cerebral arterySpecific magnetic resonance imagingInfarct volume determinationArtery occlusionCohort studyStroke treatmentCerebral arteryEndovascular treatmentPatient selection
2013
Patterns of Emergency Medical Services Use and Its Association With Timely Stroke Treatment
Ekundayo O, Saver J, Fonarow G, Schwamm L, Xian Y, Zhao X, Hernandez A, Peterson E, Cheng E. Patterns of Emergency Medical Services Use and Its Association With Timely Stroke Treatment. Circulation Cardiovascular Quality And Outcomes 2013, 6: 262-269. PMID: 23633218, DOI: 10.1161/circoutcomes.113.000089.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overChi-Square DistributionEmergency Medical ServicesEmergency Service, HospitalEthnicityFemaleGuideline AdherenceHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedMinority GroupsOdds RatioOutcome and Process Assessment, Health CarePatient Acceptance of Health CarePatient Education as TopicPractice Guidelines as TopicRegistriesRisk FactorsStrokeTime FactorsTime-to-TreatmentTransportation of PatientsTreatment OutcomeUnited StatesConceptsEmergency medical servicesStroke patientsEMS useEmergency medical services useMinority raceHealth Stroke ScoreMedical service useTreatment of strokeTissue-type plasminogen activatorEligible patientsGuidelines-StrokeSevere strokeStroke ScoreHospital arrivalOlder patientsYounger patientsHemorrhagic strokeStroke treatmentMedicare insuranceInsurance statusEMS activationDecreased oddsEMS transportService usePatients
2012
Emergency Medical Service Hospital Prenotification Is Associated With Improved Evaluation and Treatment of Acute Ischemic Stroke
Lin C, Peterson E, Smith E, Saver J, Liang L, Xian Y, Olson D, Shah B, Hernandez A, Schwamm L, Fonarow G. Emergency Medical Service Hospital Prenotification Is Associated With Improved Evaluation and Treatment of Acute Ischemic Stroke. Circulation Cardiovascular Quality And Outcomes 2012, 5: 514-522. PMID: 22787065, DOI: 10.1161/circoutcomes.112.965210.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCommunicationEmergency Medical ServicesEmergency Service, HospitalFemaleFibrinolytic AgentsGuideline AdherenceHealth Services AccessibilityHospitalsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOutcome and Process Assessment, Health CarePractice Guidelines as TopicQuality ImprovementRegistriesStrokeThrombolytic TherapyTime FactorsTime-to-TreatmentTissue Plasminogen ActivatorTreatment OutcomeUnited StatesConceptsAcute ischemic strokeTissue plasminogen activatorNeedle timeEMS prenotificationHospital prenotificationIschemic strokeEligible patientsShorter doorIntravenous tissue plasminogen activatorClustering of patientsShorter symptom onsetQuality of careGuidelines-StrokeTPA useSymptom onsetPotential strokeStroke treatmentPatientsPoisson regressionStrokeTreatment ratesIncoming patientsGreater likelihoodPrenotificationMinutesEconomic Impact of Using Additional Diagnostic Tests to Better Select Patients With Stroke for Intravenous Thrombolysis in the United Kingdom
Earnshaw S, McDade C, Chapman A, Jackson D, Schwamm L. Economic Impact of Using Additional Diagnostic Tests to Better Select Patients With Stroke for Intravenous Thrombolysis in the United Kingdom. Clinical Therapeutics 2012, 34: 1544-1558. PMID: 22695225, DOI: 10.1016/j.clinthera.2012.05.004.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingMRI selectionUsual careDiagnostic testsFavorable outcomeIncremental cost-effectiveness ratioAcute stroke treatmentPreferred diagnostic testNumber of patientsAdditional diagnostic testsCost-effectiveness ratioDecision analytic modelCTP selectionIntravenous thrombolysisStroke onsetStroke treatmentPatient selectionUK patientsPenumbral patternPatient outcomesPerfusion CTPatient historyThrombolysisPatientsPerfusion imagingRegional Variation in Recommended Treatments for Ischemic Stroke and TIA
Allen NB, Kaltenbach L, Goldstein LB, Olson DM, Smith EE, Peterson ED, Schwamm L, Lichtman JH. Regional Variation in Recommended Treatments for Ischemic Stroke and TIA. Stroke 2012, 43: 1858-1864. PMID: 22588262, DOI: 10.1161/strokeaha.112.652305.Peer-Reviewed Original ResearchConceptsDefect-free careLipid-lowering medicationsTissue-type plasminogen activatorLower oddsIschemic strokeIntravenous tissue-type plasminogen activatorSecondary stroke prevention treatmentDeep vein thrombosis prophylaxisTissue-type plasminogen activator administrationNational quality improvement programPlasminogen activatorGuideline-recommended treatmentGuidelines-Stroke hospitalsTransient ischemic attackQuarter of patientsStroke prevention treatmentBetter patient outcomesWeight loss educationQuality Improvement ProgramEligible patientsIschemic attackThrombosis prophylaxisPatient demographicsStroke treatmentMedical history
2010
Clinical Management of Acute Stroke
Rost N, Koroshetz W, González R, Schwamm L. Clinical Management of Acute Stroke. 2010, 211-220. DOI: 10.1007/978-3-642-12751-9_10.Peer-Reviewed Original ResearchAcute strokeStroke patientsPermanent brain injurySerious permanent disabilityAcute stroke managementAcute stroke treatmentMin of presentationLocal clinical pathwayNeurologic dysfunctionStroke treatmentBlood testsStroke managementConsensus guidelinesPhysical examinationClinical managementBrain injuryPermanent disabilityClinical pathwayTreatment decisionsMedical attentionCT interpretationStrokeFirst hourPatientsScan completion
2009
A Review of the Evidence for the Use of Telemedicine Within Stroke Systems of Care
Schwamm L, Holloway R, Amarenco P, Audebert H, Bakas T, Chumbler N, Handschu R, Jauch E, Knight W, Levine S, Mayberg M, Meyer B, Meyers P, Skalabrin E, Wechsler L. A Review of the Evidence for the Use of Telemedicine Within Stroke Systems of Care. Stroke 2009, 40: 2616-2634. PMID: 19423852, DOI: 10.1161/strokeaha.109.192360.Peer-Reviewed Original ResearchConceptsUse of telemedicineStroke systemsStroke treatmentAmerican Heart Association/American CollegeStroke care deliveryAcute stroke treatmentEvidence-based reviewEvidence-based recommendationsEmergency medical servicesSecondary preventionNeurological assessmentPrimary preventionEmergency departmentCardiology FoundationConsensus recommendationsAmerican CollegeClass of evidenceCare deliveryAvailable evidenceCare frameworkMedical servicesPreventionTelemedicineTreatmentLevel of certaintyEndovascular Approaches to Acute Stroke, Part 1: Drugs, Devices, and Data
Nogueira R, Schwamm L, Hirsch J. Endovascular Approaches to Acute Stroke, Part 1: Drugs, Devices, and Data. American Journal Of Neuroradiology 2009, 30: 649-661. PMID: 19279271, PMCID: PMC7051752, DOI: 10.3174/ajnr.a1486.Peer-Reviewed Original ResearchConceptsRecombinant tissue plasminogen activatorIntravenous recombinant tissue plasminogen activatorLonger treatment windowsAcute stroke treatmentHigher recanalization ratesTissue plasminogen activatorPublic health concernMechanical revascularizationAcute strokeReperfusion techniquesEndovascular therapyStroke treatmentEndovascular approachRecanalization ratePharmacologic strategiesTreatment windowUS FoodDrug AdministrationWire disruptionTheoretic advantagesPreclinical trialsHealth concernPlasminogen activatorTherapyStroke
2008
Organizing regional stroke systems of care
Park S, Schwamm L. Organizing regional stroke systems of care. Current Opinion In Neurology 2008, 21: 43-55. PMID: 18180651, DOI: 10.1097/wco.0b013e3282f4304d.Peer-Reviewed Original ResearchConceptsStroke treatmentStroke systemsHospital-based stroke careMajor public health problemRegional stroke systemAcute stroke treatmentBetter patient outcomesPublic health problemCare delivery modelsContinuous quality improvement activitiesAcute stroke expertiseAir medical transportEmergency medical servicesHealth policy changesQuality improvement activitiesStroke survivalSecondary preventionStroke unitStroke careThrombolytic therapyPrimary preventionStroke expertisePatient outcomesStroke educationHealth problems
2002
CT Angiography With Whole Brain Perfused Blood Volume Imaging
Ezzeddine M, Lev M, McDonald C, Rordorf G, Oliveira-Filho J, Aksoy F, Farkas J, Segal A, Schwamm L, Gonzalez R, Koroshetz W. CT Angiography With Whole Brain Perfused Blood Volume Imaging. Stroke 2002, 33: 959-966. PMID: 11935044, DOI: 10.1161/hs0402.105388.Peer-Reviewed Original ResearchConceptsOxfordshire Community Stroke Project classificationCTA/CTPNoncontrast CTCTP imagingInfarct localizationRapid CT scanningAcute stroke treatmentAcute stroke patientsInitial clinical assessmentMajor intracranial vesselsCTA source imagesVascular phase imagesSteady-state administrationProject classificationParenchymal phase imagesOrg 10172Oxfordshire classificationTOAST classificationAcute strokeStroke neurologistsStroke treatmentStroke patientsBlood volume imagingClinical examinationInfarct location
1999
Role for Telemedicine in Acute Stroke
Shafqat S, Kvedar J, Guanci M, Chang Y, Schwamm L. Role for Telemedicine in Acute Stroke. Stroke 1999, 30: 2141-2145. PMID: 10512919, DOI: 10.1161/01.str.30.10.2141.Peer-Reviewed Original ResearchConceptsNIH Stroke ScaleNIHSS scoreStroke neurologistsStroke ScaleAcute strokePatient's bedsideAcute stroke assessmentTotal NIHSS scoreAcute stroke treatmentEvaluation of patientsReliable clinical instrumentIschemic strokeStroke treatmentClinical outcomesStroke specialistsStroke expertiseBedside examinationStroke assessmentBedside assessmentKappa coefficientTelemedicine linkPatientsBedsideClinical instrumentsStroke