2019
Intravenous Tissue Plasminogen Activator in Stroke Mimics
Ali-Ahmed F, Federspiel J, Liang L, Xu H, Sevilis T, Hernandez A, Kosinski A, Prvu Bettger J, Smith E, Bhatt D, Schwamm L, Fonarow G, Peterson E, Xian Y. Intravenous Tissue Plasminogen Activator in Stroke Mimics. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005609. PMID: 31412730, PMCID: PMC6699639, DOI: 10.1161/circoutcomes.119.005609.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdultAgedAged, 80 and overBrain IschemiaDiagnosis, DifferentialFemaleFibrinolytic AgentsHumansIntracranial HemorrhagesMaleMiddle AgedPredictive Value of TestsRegistriesRisk AssessmentRisk FactorsStrokeThrombolytic TherapyTissue Plasminogen ActivatorTreatment OutcomeUnited StatesUnnecessary ProceduresConceptsTransient ischemic attackStroke mimicsIschemic strokeIschemic attackPrior stroke/transient ischemic attackStroke/transient ischemic attackIntravenous tissue plasminogen activatorGuidelines-Stroke registrySymptomatic intracranial hemorrhageCardiovascular risk factorsHealth Stroke ScaleHospital mortality rateAcute ischemic strokeStroke-like symptomsTissue plasminogen activatorUse of tPANonstroke diagnosisThrombolysis safetyIntravenous tPAStroke ScaleComplication rateIntracranial hemorrhagePresumed strokeRisk factorsFunctional disorders
2018
Evaluation of a score for the prehospital distinction between cerebrovascular disease and stroke mimic patients
Geisler F, Ali S, Ebinger M, Kunz A, Rozanski M, Waldschmidt C, Weber J, Wendt M, Winter B, Schwamm L, Audebert H. Evaluation of a score for the prehospital distinction between cerebrovascular disease and stroke mimic patients. International Journal Of Stroke 2018, 14: 400-408. PMID: 30303808, DOI: 10.1177/1747493018806194.Peer-Reviewed Original ResearchConceptsStroke mimic patientsIndividual patient characteristicsMimic patientsCerebrovascular diseaseStroke mimicsPatient characteristicsFocal neurological deficitsCerebrovascular disease patientsCertain patient characteristicsMobile stroke unitPre-hospital settingSevere strokeArterial hypertensionNeurological deficitsStroke unitAtrial fibrillationDisease patientsSudden onsetEmergency physiciansHospital destinationPatientsDiscriminative valueFinal analysisDiseaseStrokeValidating the TeleStroke Mimic Score
Ali S, Hubert G, Switzer J, Majersik J, Backhaus R, Shepard L, Vedala K, Schwamm L. Validating the TeleStroke Mimic Score. Stroke 2018, 49: 688-692. PMID: 29374105, PMCID: PMC5829006, DOI: 10.1161/strokeaha.117.018758.Peer-Reviewed Original ResearchConceptsStroke mimicsIschemic cerebrovascular diseaseTelestroke networkTelestroke consultationCerebrovascular diseaseReceiver-operating characteristic curve analysisAcute stroke evaluationExternal validation cohortRisk prediction scoreStroke care networksCharacteristic curve analysisStroke evaluationValidation cohortClinical differencesOriginal cohortFinal diagnosisTelestroke consultsScore's abilityGeorgia Regents UniversityDiverse cohortCare networkCurve analysisCohortConfidence intervalsPrediction score
2014
The TeleStroke Mimic (TM)‐Score: A Prediction Rule for Identifying Stroke Mimics Evaluated in a Telestroke Network
Ali SF, Viswanathan A, Singhal AB, Rost NS, Forducey PG, Davis LW, Schindler J, Likosky W, Schlegel S, Solenski N, Schwamm LH, Network O. The TeleStroke Mimic (TM)‐Score: A Prediction Rule for Identifying Stroke Mimics Evaluated in a Telestroke Network. Journal Of The American Heart Association 2014, 3: e000838. PMID: 24958778, PMCID: PMC4309074, DOI: 10.1161/jaha.114.000838.Peer-Reviewed Original ResearchConceptsStroke mimicsIschemic cerebrovascular diseaseTelestroke networkReceiver-operating characteristic curve analysisCurve analysisHealth Stroke ScaleVascular risk profileVascular risk factorsAcute stroke evaluationExternal validation cohortFinal clinical diagnosisLower mean ageROC curve analysisCharacteristic curve analysisStepwise logistic regressionTelestroke consultationStroke ScaleFacial weaknessConsecutive patientsDerivation cohortPrior seizuresStroke evaluationAlternate diagnosisCerebrovascular diseaseValidation cohort
2013
Separating Acute Stroke from Stroke Mimics in a TeleStroke Network: Differential Patient Characteristics and Exam Findings (P07.241)
Ali S, Cohen A, Viswanathan A, Feske S, Rost N, Silverman S, Anderson C, Schwamm L. Separating Acute Stroke from Stroke Mimics in a TeleStroke Network: Differential Patient Characteristics and Exam Findings (P07.241). Neurology 2013, 80 DOI: 10.1212/wnl.80.7_supplement.p07.241.Peer-Reviewed Original Research
1999
Normal diffusion-weighted MRI during stroke-like deficits
Ay H, Buonanno F, Rordorf G, Schaefer P, Schwamm L, Wu O, Gonzalez R, Yamada K, Sorensen G, Koroshetz W. Normal diffusion-weighted MRI during stroke-like deficits. Neurology 1999, 52: 1784-1792. PMID: 10371524, DOI: 10.1212/wnl.52.9.1784.Peer-Reviewed Original ResearchConceptsDiffusion-weighted MRICerebral ischemic eventsDWI abnormalitiesStroke mimicsIschemic eventsAcute ischemic strokeIschemic brain injuryTransient global amnesiaIschemic causePathophysiologic diagnosisLacunar syndromeNonischemic causesIschemic strokeLacunar infarctionNeurologic deficitsBrain ischemiaConsecutive patientsSuch patientsRadiologic dataFinal diagnosisBrain injuryCortical syndromesFunctional disordersEarly diagnosisGlobal amnesia