2022
Use of Prolonged Cardiac Rhythm Monitoring to Identify Atrial Fibrillation After Cryptogenic Stroke
Roy A, Schwamm L, Singhal A. Use of Prolonged Cardiac Rhythm Monitoring to Identify Atrial Fibrillation After Cryptogenic Stroke. Current Cardiology Reports 2022, 24: 337-346. PMID: 35171442, DOI: 10.1007/s11886-022-01652-1.Peer-Reviewed Original ResearchConceptsCryptogenic strokeAtrial fibrillationCardiac monitoringTiming of AFConsideration of anticoagulationCryptogenic stroke patientsCardiac rhythm monitoringAF detectionDetection of AFAnticoagulation initiationClinical outcomesStroke evaluationStroke patientsClinical calculatorsRhythm monitoringRecent FindingsDespiteStrokeLonger durationDefinitive researchFibrillationAdditional researchDurationOptimal typeMore investigationAnticoagulation
2018
Isolated Upper Limb Weakness From Ischemic Stroke: Mechanisms and Outcome
Topcuoglu M, Rocha E, Siddiqui A, Mills B, Silva G, Schwamm L, Lamuraglia G, Singhal A. Isolated Upper Limb Weakness From Ischemic Stroke: Mechanisms and Outcome. Journal Of Stroke And Cerebrovascular Diseases 2018, 27: 2712-2719. PMID: 30033098, DOI: 10.1016/j.jstrokecerebrovasdis.2018.05.050.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCarotid StenosisCerebral AngiographyComputed Tomography AngiographyDiffusion Magnetic Resonance ImagingDisability EvaluationEmbolismFemaleHeart DiseasesHumansMagnetic Resonance AngiographyMaleMiddle AgedMotor ActivityMotor CortexMuscle StrengthMuscle WeaknessMuscle, SkeletalPlaque, AtheroscleroticPrognosisRecovery of FunctionRetrospective StudiesRisk FactorsRupture, SpontaneousStrokeUpper ExtremityConceptsCarotid artery stenosisArtery stenosisCarotid stenosisSubcortical white matter infarctsClinical imaging featuresUpper extremity weaknessDiffusion-weighted magnetic resonance imagingUpper limb weaknessRecurrent stroke riskWhite matter infarctsMagnetic resonance imagingCardioembolic mechanismRecurrent strokeBrainstem infarctsExtremity weaknessMultiple infarctsIschemic strokeLimb weaknessStroke riskMotor stripStroke evaluationMean agePlaque ulcerationStroke mechanismInfarctsValidating the TeleStroke Mimic Score
Ali S, Hubert G, Switzer J, Majersik J, Backhaus R, Shepard L, Vedala K, Schwamm L. Validating the TeleStroke Mimic Score. Stroke 2018, 49: 688-692. PMID: 29374105, PMCID: PMC5829006, DOI: 10.1161/strokeaha.117.018758.Peer-Reviewed Original ResearchConceptsStroke mimicsIschemic cerebrovascular diseaseTelestroke networkTelestroke consultationCerebrovascular diseaseReceiver-operating characteristic curve analysisAcute stroke evaluationExternal validation cohortRisk prediction scoreStroke care networksCharacteristic curve analysisStroke evaluationValidation cohortClinical differencesOriginal cohortFinal diagnosisTelestroke consultsScore's abilityGeorgia Regents UniversityDiverse cohortCare networkCurve analysisCohortConfidence intervalsPrediction score
2015
Telestroke
Rubin M, Demaerschalk B, Schwamm L, Wechsler L. Telestroke. 2015, 47-57. DOI: 10.1007/978-1-4939-2349-6_5.Peer-Reviewed Original ResearchSecondary preventionStroke careHealth Stroke Scale scoreMajor public health problemStroke Scale scoreAcute ischemic strokeAcute stroke carePrimary stroke centerAcute stroke evaluationPrevention of complicationsEducation of patientsPublic health problemPrehospital emergency medical systemEmergency medical systemExcellent interrater agreementStroke practiceStroke providersTelestroke modelIschemic strokeStroke centersStroke evaluationCerebrovascular diseaseEvidence-based practicePoststroke outcomesBedside assessment
2014
The TeleStroke Mimic (TM)‐Score: A Prediction Rule for Identifying Stroke Mimics Evaluated in a Telestroke Network
Ali SF, Viswanathan A, Singhal AB, Rost NS, Forducey PG, Davis LW, Schindler J, Likosky W, Schlegel S, Solenski N, Schwamm LH, Network O. The TeleStroke Mimic (TM)‐Score: A Prediction Rule for Identifying Stroke Mimics Evaluated in a Telestroke Network. Journal Of The American Heart Association 2014, 3: e000838. PMID: 24958778, PMCID: PMC4309074, DOI: 10.1161/jaha.114.000838.Peer-Reviewed Original ResearchConceptsStroke mimicsIschemic cerebrovascular diseaseTelestroke networkReceiver-operating characteristic curve analysisCurve analysisHealth Stroke ScaleVascular risk profileVascular risk factorsAcute stroke evaluationExternal validation cohortFinal clinical diagnosisLower mean ageROC curve analysisCharacteristic curve analysisStepwise logistic regressionTelestroke consultationStroke ScaleFacial weaknessConsecutive patientsDerivation cohortPrior seizuresStroke evaluationAlternate diagnosisCerebrovascular diseaseValidation cohort
2010
Cost-Effectiveness of CT Perfusion for Selecting Patients for Intravenous Thrombolysis: A US Hospital Perspective
Jackson D, Earnshaw S, Farkouh R, Schwamm L. Cost-Effectiveness of CT Perfusion for Selecting Patients for Intravenous Thrombolysis: A US Hospital Perspective. American Journal Of Neuroradiology 2010, 31: 1669-1674. PMID: 20538823, PMCID: PMC7965001, DOI: 10.3174/ajnr.a2138.Peer-Reviewed Original ResearchConceptsHospital perspectiveUnenhanced CTExtent of penumbraLife-year savedUS hospital perspectiveAcute stroke evaluationSelection of patientsCT-based methodClinical trial dataDecision analytic modelCTP selectionIntravenous thrombolysisIschemic strokeClinical outcomesStroke evaluationPatient populationCT perfusionFavorable outcomeRoutine CTClinical trialsPatientsTrial dataMultivariate sensitivity analysisHospitalTPA treatment