2024
Clinically relevant findings on 24-h head CT after acute stroke therapy: The 24-h CT score.
Zhang B, King A, Voetsch B, Silverman S, Schwamm L, Ji X, Singhal A. Clinically relevant findings on 24-h head CT after acute stroke therapy: The 24-h CT score. International Journal Of Stroke 2024, 17474930241289992. PMID: 39324561, DOI: 10.1177/17474930241289992.Peer-Reviewed Original ResearchCT scoreCT findingsHead CTClinically relevant findingsFollow-up head CTRoutine head computed tomographyHead CT findingsHead computed tomographyConsecutive acute ischemic stroke patientsBlood pressure goalsAcute ischemic stroke patientsLow-risk groupMedium-risk groupAdministration of mannitolHigh-risk groupMultivariate logistic regressionAcute stroke therapyComprehensive stroke centerIschemic stroke patientsBlood glucose levelsCT abnormalitiesAntithrombotic treatmentRelevant findingsHypertonic salineRetrospective study
2019
The Mild and Rapidly Improving Stroke Study (MaRISS): Rationale and design
Romano J, Gardener H, Campo-Bustillo I, Khan Y, Riley N, Tai S, Sacco R, Khatri P, Smith E, Schwamm L. The Mild and Rapidly Improving Stroke Study (MaRISS): Rationale and design. International Journal Of Stroke 2019, 14: 983-986. PMID: 31496438, DOI: 10.1177/1747493019873595.Peer-Reviewed Original ResearchConceptsStroke symptomsStroke Impact Scale-16Actual treatment ratesMild ischemic strokePrimary safety outcomeSymptomatic hemorrhagic transformationProportion of patientsThird of patientsProspective observational studyEffect of alteplaseAcute stroke trialsLong-term outcomesPredictors of outcomeAlteplase treatmentHemorrhagic transformationIschemic strokeRankin ScaleSecondary outcomesBarthel IndexPrimary outcomeResidual disabilityStroke presentationRetrospective studyStroke StudyStroke trials
2017
Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke
Yaghi S, Willey JZ, Cucchiara B, Goldstein JN, Gonzales NR, Khatri P, Kim LJ, Mayer SA, Sheth KN, Schwamm LH. Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke. Stroke 2017, 48: e343-e361. PMID: 29097489, DOI: 10.1161/str.0000000000000152.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageAcute ischemic strokeIschemic strokeSystemic thrombolysisCase seriesIntravenous thrombolytic therapyMainstay of treatmentSmall case seriesTreatment of patientsBlood-brain barrierWriting group membersHemorrhagic transformationIntravenous alteplaseFeared complicationSevere complicationsPrompt diagnosisRandomized trialsThrombolytic therapyIntracranial hemorrhageRetrospective studyRisk factorsEarly correctionAlteplaseStrokeLiterature review
2015
Treatment and Outcome of Thrombolysis-Related Hemorrhage: A Multicenter Retrospective Study
Yaghi S, Boehme A, Dibu J, Guerrero C, Ali S, Martin-Schild S, Sands K, Noorian A, Blum C, Chaudhary S, Schwamm L, Liebeskind D, Marshall R, Willey J. Treatment and Outcome of Thrombolysis-Related Hemorrhage: A Multicenter Retrospective Study. JAMA Neurology 2015, 72: 1-7. PMID: 26501741, PMCID: PMC4845894, DOI: 10.1001/jamaneurol.2015.2371.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageRecombinant tissue plasminogen activatorMulticenter retrospective studyHematoma expansionHospital mortalityMedian timeRetrospective studyIntravenous recombinant tissue plasminogen activatorHealth Stroke Scale scoreParenchymal hematoma type 2Code status changeOutcome of thrombolysisStroke-Monitoring StudyComprehensive stroke centerHospital mortality rateOutcomes of patientsStroke Scale scoreTissue plasminogen activatorIschemic strokePrimary outcomeRtPA therapySecondary outcomesStroke centersSymptom onsetIntracerebral hemorrhage
2002
T HE E VOLVING R OLE OF H ELICOPTER E MERGENCY M EDICAL S ERVICES IN THE T RANSFER OF S TROKE P ATIENTS TO S PECIALIZED C ENTERS
Thomas S, Kociszewski C, Schwamm L, Wedel S. T HE E VOLVING R OLE OF H ELICOPTER E MERGENCY M EDICAL S ERVICES IN THE T RANSFER OF S TROKE P ATIENTS TO S PECIALIZED C ENTERS. Prehospital Emergency Care 2002, 6: 210-214. PMID: 11962569, DOI: 10.1080/10903120290938562.Peer-Reviewed Original ResearchConceptsHospital arrivalERA patientsIschemic strokeThrombolysis eraSymptom onsetThrombolytic therapyInterfacility transportHEMS activationHelicopter emergency medical services (HEMS) programsE MERGENCY M EDICAL S ERVICESHospital requestsLogistic regression analysisHelicopter EMS (HEMS) transportEmergency medical services programPearson chi-squarePatient demographicsHEMS transportRetrospective studyStroke patientsInterfacility transferP atientsEMS transportHelicopter transportPatientsDrug Administration