2024
Digital Health for Oncological Care
Cohen A, Schwamm L. Digital Health for Oncological Care. The Cancer Journal 2024, 30: 34-39. PMID: 38265925, DOI: 10.1097/ppo.0000000000000693.Peer-Reviewed Original ResearchConceptsDigital health toolsHealth care systemMental health solutionsDigital biomarkersRemote patient monitoringOncology careCancer screeningHealth continuumCare systemHealth toolsHealth solutionsDigital healthDigital therapeuticsCareHealthTelemedicinePatient monitoringPreventionRecommendationsOncologyDiagnosisOutcomesScreening
2023
Most Promising Approaches to Improve Stroke Outcomes: The Stroke Treatment Academic Industry Roundtable XII Workshop
Wechsler L, Adeoye O, Alemseged F, Bahr-Hosseini M, Deljkich E, Favilla C, Fisher M, Grotta J, Hill M, Kamel H, Khatri P, Lyden P, Mirza M, Nguyen T, Samaniego E, Schwamm L, Selim M, Silva G, Yavagal D, Yenari M, Zachrison K, Boltze J, Yaghi S, Roundtable O. Most Promising Approaches to Improve Stroke Outcomes: The Stroke Treatment Academic Industry Roundtable XII Workshop. Stroke 2023, 54: 3202-3213. PMID: 37886850, DOI: 10.1161/strokeaha.123.044279.Peer-Reviewed Original ResearchSMS-text messaging for collecting outcome measures after acute stroke
DiCarlo J, Erler K, Petrilli M, Emerson K, Gochyyev P, Schwamm L, Lin D. SMS-text messaging for collecting outcome measures after acute stroke. Frontiers In Digital Health 2023, 5: 1043806. PMID: 36910572, PMCID: PMC9996089, DOI: 10.3389/fdgth.2023.1043806.Peer-Reviewed Original ResearchModified Rankin ScaleAcute strokeOutcomes Measurement Information System (PROMIS) Global-10Acute stroke treatmentText messaging programsNIH Stroke ScaleOutcome data collectionHospitalization dischargeSMS text messagingHospital stayStroke ScaleMRS scoreRankin ScaleStroke treatmentFunctional outcomePROM scoresOutcome measuresWeighted Cohen's kappaPatientsSignificant associationStrokeTraditional followSMS textOutcomesParticipant satisfaction
2021
Outcomes of Endovascular Therapy in Patients With Prestroke Mobility Impairment
Beekman R, Sun JL, Alhanti B, Schwamm LH, Smith EE, Bhatt DL, Xian Y, Shah S, Lytle BL, Fonarow GC, Sheth KN. Outcomes of Endovascular Therapy in Patients With Prestroke Mobility Impairment. Stroke 2021, 52: e725-e728. PMID: 34517771, DOI: 10.1161/strokeaha.121.034464.Peer-Reviewed Original ResearchConceptsEndovascular thrombectomyGuidelines-Stroke registrySymptomatic intracranial hemorrhageMobility impairmentsLogistic regression modelsHospital deathEndovascular therapyClinical benefitIntracranial hemorrhageAdverse outcomesClinical trialsThrombectomyPatientsOutcomesFurther studiesImpairmentRegression modelsNational data setsSafetyHemorrhageRegistryTherapyPopulationHospiceTrials
2020
Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States.
Prabhakaran S, Messé S, Kleindorfer D, Smith E, Fonarow G, Xu H, Zhao X, Lytle B, Cigarroa J, Schwamm L. Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States. Neurology Clinical Practice 2020, 10: 396-405. PMID: 33299667, PMCID: PMC7717635, DOI: 10.1212/cpj.0000000000000736.Peer-Reviewed Original ResearchCryptogenic strokeIschemic strokeStroke etiologyDischarge outcomesHospital treatmentHospital characteristicsMultivariable logistic regressionGWTG-StrokeStroke RegistryNationwide registryMultivariable analysisPatientsLower mortalityHigh mortalityNationwide dataLogistic regressionSubtypesStrokeNational InstituteScale scaleOutcomesTreatmentRegistryHospitalEtiologyProbing the Effective Treatment Thresholds for Alteplase in Acute Ischemic Stroke With Regression Discontinuity Designs
Naidech A, Lawlor P, Xu H, Fonarow G, Xian Y, Smith E, Schwamm L, Matsouaka R, Prabhakaran S, Marinescu I, Kording K. Probing the Effective Treatment Thresholds for Alteplase in Acute Ischemic Stroke With Regression Discontinuity Designs. Frontiers In Neurology 2020, 11: 961. PMID: 32982952, PMCID: PMC7492202, DOI: 10.3389/fneur.2020.00961.Peer-Reviewed Original ResearchTreatment thresholdOutcomes of patientsAcute ischemic strokeCohort of patientsPatient demographic characteristicsIschemic strokeControlled TrialsStroke interventionClinical outcomesClinical careEffective treatmentLarger sample sizeMedical interventionsPatientsDemographic characteristicsGold standardAlteplaseInterventionTreatmentContinuous variablesOutcomesLimited populationSample sizeTreatment timePotential reasons
2019
Thrombolysis in young adults with stroke: Findings from Get With The Guidelines-Stroke.
Dodds J, Xian Y, Sheng S, Fonarow G, Bhatt D, Matsouaka R, Schwamm L, Peterson E, Smith E. Thrombolysis in young adults with stroke: Findings from Get With The Guidelines-Stroke. Neurology 2019, 92: e2784-e2792. PMID: 31092622, DOI: 10.1212/wnl.0000000000007653.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeTissue plasminogen activatorIschemic strokeOlder patientsYounger patientsYears of ageSymptomatic intracranial hemorrhage rateYoung adultsGuidelines-Stroke registryIntracranial hemorrhage rateGuidelines-StrokeHospital mortalityHospital arrivalHemorrhage rateIntracranial hemorrhageMultivariable modelPatientsBetter outcomesStrokePlasminogen activatorTPA treatmentTreatmentAdultsAgeOutcomes
2018
Protocols for Endovascular Stroke Treatment Diminish the Weekend Effect Through Improvements in Off-Hours Care
Raymond S, Akbik F, Stapleton C, Mehta B, Chandra R, Gonzalez R, Rabinov J, Schwamm L, Patel A, Hirsch J, Leslie-Mazwi T. Protocols for Endovascular Stroke Treatment Diminish the Weekend Effect Through Improvements in Off-Hours Care. Frontiers In Neurology 2018, 9: 1106. PMID: 30619062, PMCID: PMC6305592, DOI: 10.3389/fneur.2018.01106.Peer-Reviewed Original ResearchTime of presentationTreatment latencyTreatment intervalEndovascular stroke treatmentProspective observational cohortOff-hour careAcute strokeMedian doorObservational cohortConsecutive patientsEndovascular therapyStroke treatmentStroke carePuncture timeFunctional outcomeProtocol adherenceThrombolysis candidatesInstitutional protocolPatient outcomesWeekend effectProtocol experienceStudy periodOutcomesPatientsRegular work hours
2017
Visual Aids for Patient, Family, and Physician Decision Making About Endovascular Thrombectomy for Acute Ischemic Stroke
Tokunboh I, Vales Montero M, Zopelaro Almeida M, Sharma L, Starkman S, Szeder V, Jahan R, Liebeskind D, Gonzalez N, Demchuk A, Froehler M, Goyal M, Lansberg M, Lutsep H, Schwamm L, Saver J. Visual Aids for Patient, Family, and Physician Decision Making About Endovascular Thrombectomy for Acute Ischemic Stroke. Stroke 2017, 49: 90-97. PMID: 29222229, DOI: 10.1161/strokeaha.117.018715.Peer-Reviewed Original ResearchConceptsAcute cerebral ischemiaEndovascular thrombectomyBetter disability outcomesCerebral ischemiaDisability outcomesTPA-eligible patientsAcute ischemic strokeLarge vessel occlusionReperfusion treatmentTerritory infarctsIschemic strokeRankin ScaleVessel occlusionThrombectomyPatientsPhysician's decisionHealthcare providersTrial dataAdverse effectsOutcomesTreatment effectsIschemiaVisual decision aidsTPADecision aidRegional Variation in 30-Day Ischemic Stroke Outcomes for Medicare Beneficiaries Treated in Get With The Guidelines–Stroke Hospitals
Thompson M, Zhao X, Bekelis K, Gottlieb D, Fonarow G, Schulte P, Xian Y, Lytle B, Schwamm L, Smith E, Reeves M. Regional Variation in 30-Day Ischemic Stroke Outcomes for Medicare Beneficiaries Treated in Get With The Guidelines–Stroke Hospitals. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003604. PMID: 28798017, DOI: 10.1161/circoutcomes.117.003604.Peer-Reviewed Original ResearchMeSH KeywordsAdministrative Claims, HealthcareAgedBrain IschemiaDatabases, FactualFee-for-Service PlansFemaleGuideline AdherenceHealth ResourcesHealthcare DisparitiesHospitalsHumansInsurance BenefitsMaleMedicarePatient ReadmissionPractice Guidelines as TopicProcess Assessment, Health CareQuality Indicators, Health CareRegistriesRisk FactorsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsReadmission ratesHospital characteristicsHRR levelHealthcare resourcesGuidelines-Stroke hospitalsGuidelines-Stroke registryHealthcare resource dataIschemic stroke outcomeThirty-day mortalityIschemic stroke mortalityHospital referral region levelStroke outcomeHospital factorsPatient characteristicsStroke mortalityCare measuresMedicare beneficiariesMedicare feeMortalityDartmouth AtlasPatientsRegional variationHealth careOutcomesReadmissionThe American Heart Association’s Get With the Guidelines (GWTG)-Stroke development and impact on stroke care
Ormseth CH, Sheth KN, Saver JL, Fonarow GC, Schwamm LH. The American Heart Association’s Get With the Guidelines (GWTG)-Stroke development and impact on stroke care. Stroke And Vascular Neurology 2017, 2: 94. PMID: 28959497, PMCID: PMC5600018, DOI: 10.1136/svn-2017-000092.Peer-Reviewed Original ResearchConceptsStroke care deliveryAmerican Heart AssociationHeart AssociationCare deliveryEvidence-based careContinuous quality improvement initiativesQuality improvement initiativesInpatient outcomesStroke ProgramPatient characteristicsStroke outcomeStroke careStroke developmentVoluntary registryPatient outcomesHospital adherenceImprovement initiativesOutcomesCareGuidelinesAssociationGWTGDeliveryRegistry
2015
National stroke registries for monitoring and improving the quality of hospital care: A systematic review
Cadilhac D, Kim J, Lannin N, Kapral M, Schwamm L, Dennis M, Norrving B, Meretoja A. National stroke registries for monitoring and improving the quality of hospital care: A systematic review. International Journal Of Stroke 2015, 11: 28-40. PMID: 26763018, DOI: 10.1177/1747493015607523.Peer-Reviewed Original ResearchConceptsStroke careNational strokePatient outcomesNational Stroke RegistryAcute stroke careEvidence-based careHospital-based strokeStroke RegistryNational registryHospital careInitial keyword searchRegistrySystematic reviewPatient consentData linkagePotential papersSystematic searchMost registriesCareStrokeOutcomesBetter awarenessRoutine monitoringCurrent useBetter access
2013
Impact of macroeconomic status on prehospital management, in-hospital care and functional outcome of acute stroke in China
Ji R, Wang D, Liu G, Shen H, Wang Y, Li H, Schwamm L, Wang Y. Impact of macroeconomic status on prehospital management, in-hospital care and functional outcome of acute stroke in China. Journal Of Clinical Practice 2013, 10: 701-712. DOI: 10.2217/cpr.13.68.Peer-Reviewed Original ResearchPrehospital managementFunctional outcomeChina National Stroke RegistryModified Rankin Scale scoreOpportunity-based scoreNational Stroke RegistryRankin Scale scoreGood functional outcomeGeneralized estimation equationsStroke RegistryIschemic strokeHospital careScale scoreHospital qualityStrokeComposite measureCareOutcomesScores
2011
Stroke Quality Metrics
Parker C, Schwamm L, Fonarow G, Smith E, Reeves M. Stroke Quality Metrics. Stroke 2011, 43: 155-162. PMID: 21980213, DOI: 10.1161/strokeaha.111.635011.Peer-Reviewed Original ResearchConceptsPatient-centered outcomesQuality of carePublic reportingStroke metricsAcute hospital settingHigh-quality studiesPositive associationQuality improvement activitiesStroke outcomeStroke unitEmbase databasesEligible studiesPatient outcomesHospital settingEligibility criteriaSystematic reviewReported associationsHospital certificationProvider reimbursementOutcomesAssociationLimited associationCareQuality improvementCompliance
2010
Hospital Certification for Optimizing Cardiovascular Disease and Stroke Quality of Care and Outcomes
Fonarow G, Gregory T, Driskill M, Stewart M, Beam C, Butler J, Jacobs A, Meltzer N, Peterson E, Schwamm L, Spertus J, Yancy C, Tomaselli G, Sacco R. Hospital Certification for Optimizing Cardiovascular Disease and Stroke Quality of Care and Outcomes. Circulation 2010, 122: 2459-2469. PMID: 21098429, DOI: 10.1161/cir.0b013e3182011a81.Peer-Reviewed Original ResearchConceptsAmerican Heart Association/American Stroke AssociationAmerican Stroke AssociationCardiovascular diseaseStroke AssociationStroke qualityEvidence-based careStroke patientsLeading causeCurrent evidenceHospital accreditationStrokeDiseaseHealthcare expendituresHospital certificationCareOutcomesPatientsFuture strategiesAssociationHealthcare organizationsHospitalMixed findingsMortality
2005
Poor Outcomes in Patients Who Do Not Receive Intravenous Tissue Plasminogen Activator Because of Mild or Improving Ischemic Stroke
Smith E, Abdullah A, Petkovska I, Rosenthal E, Koroshetz W, Schwamm L. Poor Outcomes in Patients Who Do Not Receive Intravenous Tissue Plasminogen Activator Because of Mild or Improving Ischemic Stroke. Stroke 2005, 36: 2497-2499. PMID: 16210552, DOI: 10.1161/01.str.0000185798.78817.f3.Peer-Reviewed Original ResearchConceptsIntravenous tissue plasminogen activatorTissue plasminogen activatorNeurological worseningPoor outcomeHealth Stroke Scale scoreProspective single-center studyPlasminogen activatorStroke Scale scoreSingle-center studyIschemic stroke symptomsTPA eligibilityHome dischargeIschemic strokeNeurological deficitsSymptom onsetStroke symptomsSeverity criteriaPatientsScale scoreNational InstituteSubstantial minoritySymptomsStrokeWorseningOutcomes