2023
Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users
Das A, Gökçal E, Fouks A, Horn M, Regenhardt R, Viswanathan A, Singhal A, Schwamm L, Greenberg S, Gurol M. Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users. Journal Of Neurology 2023, 270: 5578-5588. PMID: 37548681, PMCID: PMC11111216, DOI: 10.1007/s00415-023-11916-7.Peer-Reviewed Original ResearchPrior cerebrovascular eventsAtrial volume indexVentricular hypertrophyCerebrovascular eventsNOAC usersAtrial sizeIS recurrenceSevere white matter hyperintensitiesVolume indexCerebral small vessel diseaseOral anticoagulant usersChronic renal failureRisk of strokeCox regression analysisQuaternary care centerSmall vessel diseaseAge-matched controlsWhite matter hyperintensitiesMultivariable regression modelsAnticoagulant usersApixaban useDabigatran useResults112 patientsMultivariable adjustmentOral anticoagulants
2022
Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants
Das A, Gökçal E, Regenhardt R, Warren A, Biffi A, Goldstein J, Kimberly W, Viswanathan A, Schwamm L, Rosand J, Greenberg S, Gurol M. Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants. Journal Of Neurology 2022, 269: 6589-6596. PMID: 35997817, PMCID: PMC10947801, DOI: 10.1007/s00415-022-11333-2.Peer-Reviewed Original ResearchConceptsCortical superficial siderosisPrior ischemic strokeDOAC usersCerebral microbleedsWhite matter hyperintensitiesIschemic strokeSevere white matter hyperintensitiesOral anticoagulant usageDirect oral anticoagulantsSingle referral centerHigh hemorrhagic riskCoronary artery diseaseAge-matched controlsMultivariable regression modelsDOAC therapyICH cohortPrior strokeOral anticoagulantsSuperficial siderosisBaseline demographicsReferral centerSmoking historyArtery diseaseConclusionsRisk factorsHemorrhage risk
2012
Predictors of Adherence to Performance Measures in Patients with Acute Myocardial Infarction
Kumbhani D, Fonarow G, Cannon C, Hernandez A, Peterson E, Peacock W, Laskey W, Pan W, Schwamm L, Bhatt D, Committee and Investigators G. Predictors of Adherence to Performance Measures in Patients with Acute Myocardial Infarction. The American Journal Of Medicine 2012, 126: 74.e1-74.e9. PMID: 22925314, DOI: 10.1016/j.amjmed.2012.02.025.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionGuidelines-Coronary Artery Disease registryAcute myocardial infarction treatmentAdherence modelCertain high-risk populationsGuideline-recommended therapiesLogistic multivariable regression modelsHigh-risk populationGuideline-based carePredictors of adherenceQuality improvement interventionsMultivariable regression modelsMyocardial infarction treatmentEligible patientsHospital characteristicsWorse adherenceSummary scoresDisease RegistryInfarction treatmentPatientsImprovement interventionsGreater adherenceInfarctionAdherence
2010
Patterns and Predictors of Discharge Statin Prescription Among Hospitalized Patients With Intracerebral Hemorrhage
Ovbiagele B, Schwamm L, Smith E, Hernandez A, Olson D, Pan W, Fonarow G, Saver J. Patterns and Predictors of Discharge Statin Prescription Among Hospitalized Patients With Intracerebral Hemorrhage. Stroke 2010, 41: 2271-2277. PMID: 20724709, DOI: 10.1161/strokeaha.110.593228.Peer-Reviewed Original ResearchConceptsDischarge statin prescriptionStatin prescriptionIntracerebral hemorrhageStatin useStatin treatmentPrior stroke/transient ischemic attackStroke/transient ischemic attackCholesterol Levels (SPARCL) trialStatin treatment armsLogistic multivariable regression modelsTransient ischemic attackHemorrhagic stroke riskHigher future riskMultivariable regression modelsGuidelines-StrokeIschemic attackEligible patientsStroke preventionIschemic eventsStroke riskHospitalized patientsHemorrhagic strokeTreatment armsMean ageFemale sex