2023
Insurance-Based Disparities in Stroke Center Access in California: A Network Science Approach
Zachrison K, Hsia R, Schwamm L, Yan Z, Samuels-Kalow M, Reeves M, Camargo C, Onnela J. Insurance-Based Disparities in Stroke Center Access in California: A Network Science Approach. Circulation Cardiovascular Quality And Outcomes 2023, 16: e009868. PMID: 37746725, PMCID: PMC10592016, DOI: 10.1161/circoutcomes.122.009868.Peer-Reviewed Original ResearchConceptsInsurance-based disparitiesStroke centersEmergency departmentHospital clustersInitial emergency departmentIschemic stroke admissionsHospital emergency departmentClusters of hospitalsLogistic regression modelsStroke admissionsUninsured patientsPatient insuranceLower oddsPatientsLess strokeCenter accessOddsCenter transferHospitalLikelihood of transferInsurance groupsRegression modelsLower proportionDepartmentAssociation
2022
Temporal trends and rural–urban disparities in cerebrovascular risk factors, in-hospital management and outcomes in ischaemic strokes in China from 2005 to 2015: a nationwide serial cross-sectional survey
Wang C, Gu H, Zhang X, Jiang Y, Li H, Bettger J, Meng X, Dong K, Wangqin R, Yang X, Wang M, Liu C, Liu L, Tang B, Li G, Xu Y, He Z, Yang Y, Yip W, Fonarow G, Schwamm L, Xian Y, Zhao X, Wang Y, Wang Y, Li Z. Temporal trends and rural–urban disparities in cerebrovascular risk factors, in-hospital management and outcomes in ischaemic strokes in China from 2005 to 2015: a nationwide serial cross-sectional survey. Stroke And Vascular Neurology 2022, 8: 34-50. PMID: 35985768, PMCID: PMC9985802, DOI: 10.1136/svn-2022-001552.Peer-Reviewed Original ResearchConceptsCerebrovascular risk factorsHospital mortalityIschemic strokeRisk factorsComposite outcomeRural-urban disparitiesUrban hospitalHospital managementSecondary prevention treatmentSerial cross-sectional surveysHospital admission ratesIschemic stroke admissionsTwo-stage random sampling surveyCause of mortalityCross-sectional surveyHospital outcomesStroke admissionsCurrent smokingHospital admissionHospital burdenAdmission ratesMedical advicePrevention treatmentTemporal improvementHospital
2021
Associations of Medicaid Expansion With Access to Care, Severity, and Outcomes for Acute Ischemic Stroke
McGee B, Seagraves K, Smith E, Xian Y, Zhang S, Alhanti B, Matsouaka R, Reeves M, Schwamm L, Fonarow G. Associations of Medicaid Expansion With Access to Care, Severity, and Outcomes for Acute Ischemic Stroke. Circulation Cardiovascular Quality And Outcomes 2021, 14: e007940. PMID: 34587752, DOI: 10.1161/circoutcomes.121.007940.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeLow-income cohortSkilled nursing facilitiesIschemic strokeMedicaid expansionStroke admissionsNonexpansion statesNursing facilitiesLow-income US populationHigh stroke burdenPrimary stroke preventionOdds of dischargeIschemic stroke admissionsExpansion statesSeverity of presentationLevel of disabilityReceipt of rehabilitationHealth insurance statusHealth insurance coverageHospital mortalityUninsured hospitalizationsStroke preventionDischarge dispositionStroke burdenStroke outcome
2016
Differences in Acute Ischemic Stroke Quality of Care and Outcomes by Primary Stroke Center Certification Organization
Man S, Cox M, Patel P, Smith E, Reeves M, Saver J, Bhatt D, Xian Y, Schwamm L, Fonarow G. Differences in Acute Ischemic Stroke Quality of Care and Outcomes by Primary Stroke Center Certification Organization. Stroke 2016, 48: 412-419. PMID: 28008094, DOI: 10.1161/strokeaha.116.014426.Peer-Reviewed Original ResearchConceptsHealthcare Facilities Accreditation ProgramPSC certificationStroke patientsJoint CommissionIntravenous tissue-type plasminogen activator useHospital risk-adjusted mortalityAcute ischemic stroke patientsStroke qualityAcute ischemic stroke admissionsCare qualityPrimary stroke center certificationGuidelines-Stroke hospitalsStroke center certificationIschemic stroke patientsIschemic stroke admissionsRisk-adjusted mortalityEvidence-based careSystems of careAccreditation programGuidelines-StrokeHospital outcomesNeedle timeStroke admissionsCenter certificationGroup of hospitalsAssociation of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke
Song S, Fonarow G, Olson D, Liang L, Schulte P, Hernandez A, Peterson E, Reeves M, Smith E, Schwamm L, Saver J. Association of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke. Stroke 2016, 47: 1294-1302. PMID: 27079809, PMCID: PMC4975426, DOI: 10.1161/strokeaha.115.011874.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke admissionsGWTG-Stroke programIschemic stroke admissionsClinical outcomesStroke admissionsMedicare beneficiariesAcute care US hospitalsHospital-based quality improvement programsGWTG-Stroke hospitalsImproved functional outcomesAmerican Heart AssociationQuality Improvement ProgramGWTG-StrokePostdischarge mortalityAcute strokeIschemic strokeFunctional outcomeHeart AssociationNonparticipating hospitalsStroke hospitalsHospital participationUS hospitalsHospitalPre periodSimilar hospitals
2015
Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack
O'Brien E, Zhao X, Fonarow G, Schulte P, Dai D, Smith E, Schwamm L, Bhatt D, Xian Y, Saver J, Reeves M, Peterson E, Hernandez A. Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack. Circulation Cardiovascular Quality And Outcomes 2015, 8: s117-s124. PMID: 26515199, DOI: 10.1161/circoutcomes.115.002048.Peer-Reviewed Original ResearchConceptsTransient ischemic attackDefect-free careIschemic strokeIschemic stroke riskQuality of careIschemic attackStroke riskCare measuresRisk scoreOverall hospital admission rateRisk score quintilesYear post dischargeLow-risk patientsHospital admission ratesIschemic stroke admissionsPrevious myocardial infarctionAbsence of strokeMedicare inpatient claimsCox proportional hazardsModerate discriminative performanceTIA patientsCause mortalityCessation counselingStroke admissionsBaseline demographics
2013
Comparison of Ischemic Stroke Outcomes and Patient and Hospital Characteristics by Race/Ethnicity and Socioeconomic Status
Hanchate A, Schwamm L, Huang W, Hylek E. Comparison of Ischemic Stroke Outcomes and Patient and Hospital Characteristics by Race/Ethnicity and Socioeconomic Status. Stroke 2013, 44: 469-476. PMID: 23306327, PMCID: PMC3595403, DOI: 10.1161/strokeaha.112.669341.Peer-Reviewed Original ResearchConceptsRace/ethnicityAcute ischemic strokeInpatient mortalityRisk-adjusted ratesIschemic strokeSocioeconomic statusBlack patientsArea patientsNonfederal acute care hospitalsRisk-adjusted inpatient mortalityIschemic stroke outcomeInpatient mortality rateIschemic stroke admissionsCrude inpatient mortality rateLength of stayPatient's zip codeAcute care hospitalsLonger lengthStroke admissionsStroke outcomeStroke severityCare hospitalDischarge outcomesWhite patientsMechanical ventilation
2011
Representativeness of the Get With The Guidelines–Stroke Registry
Reeves M, Fonarow G, Smith E, Pan W, Olson D, Hernandez A, Peterson E, Schwamm L. Representativeness of the Get With The Guidelines–Stroke Registry. Stroke 2011, 43: 44-49. PMID: 21980197, DOI: 10.1161/strokeaha.111.626978.Peer-Reviewed Original ResearchConceptsIschemic stroke admissionsGWTG-Stroke hospitalsGWTG-StrokeMedicare cohortStroke admissionsStroke hospitalsIschemic strokePatient characteristicsMedicare patientsGuidelines-Stroke registryGWTG-Stroke programIschemic stroke populationService Medicare patientsAcute ischemic strokeLength of stayHospital mortalityDischarge homeHospital outcomesAcute strokeStroke populationHospital characteristicsMedicare beneficiariesAdmissionHospitalNational feeAre Quality Improvements in the Get With The Guidelines-Stroke Program Related to Better Care or Better Data Documentation?
Reeves M, Grau-Sepulveda M, Fonarow G, Olson D, Smith E, Schwamm L. Are Quality Improvements in the Get With The Guidelines-Stroke Program Related to Better Care or Better Data Documentation? Circulation Cardiovascular Quality And Outcomes 2011, 4: 503-511. PMID: 21828344, DOI: 10.1161/circoutcomes.111.961755.Peer-Reviewed Original ResearchConceptsGuidelines-Stroke programAtrial fibrillation/flutterIntravenous recombinant tissue plasminogen activator (rt-PA) therapyRecombinant tissue plasminogen activator therapyDeep vein thrombosis prophylaxisTissue plasminogen activator therapyBetter careTarget populationGWTG-Stroke hospitalsIschemic stroke admissionsPlasminogen activator therapyNumber of patientsProportion of subjectsData collection formDischarge antithromboticsEarly antithromboticsThrombosis prophylaxisTreatment contraindicationsEligible subjectsStroke admissionsActivator therapySmoking cessationLipid therapyMeasure complianceContraindications
2010
Age-Related Differences in Characteristics, Performance Measures, Treatment Trends, and Outcomes in Patients With Ischemic Stroke
Fonarow G, Reeves M, Zhao X, Olson D, Smith E, Saver J, Schwamm L. Age-Related Differences in Characteristics, Performance Measures, Treatment Trends, and Outcomes in Patients With Ischemic Stroke. Circulation 2010, 121: 879-891. PMID: 20142445, DOI: 10.1161/circulationaha.109.892497.Peer-Reviewed Original ResearchConceptsIschemic stroke patientsOlder patientsIschemic strokeAge-related differencesAge groupsClinical characteristicsStroke patientsTreatment gapGuideline-recommended therapiesGuidelines-Stroke programWorse poststroke outcomesEarly clinical outcomesAcute ischemic strokeLarge contemporary cohortIschemic stroke admissionsHospital mortalityHospital outcomesStroke admissionsYounger patientsClinical outcomesContemporary cohortRecent smokersAtrial fibrillationMean agePoststroke outcomes
2009
Quality of Care in Women With Ischemic Stroke in the GWTG Program
Reeves M, Fonarow G, Zhao X, Smith E, Schwamm L. Quality of Care in Women With Ischemic Stroke in the GWTG Program. Stroke 2009, 40: 1127-1133. PMID: 19211482, DOI: 10.1161/strokeaha.108.543157.Peer-Reviewed Original ResearchConceptsQuality of careIschemic strokeAcute ischemic stroke admissionsMultivariable logistic regression modelDefect-free careGuidelines-Stroke programGWTG-Stroke programWorse poststroke outcomesIschemic stroke admissionsPast medical historySex differencesLogistic regression modelsSex-based differencesStroke admissionsCrude mortalityAtrial fibrillationMedical historyPoststroke outcomesHeart diseaseRisk adjustmentCareWomenFurther studiesMenStroke
2008
Off-Hour Admission and In-Hospital Stroke Case Fatality in the Get With The Guidelines-Stroke Program
Reeves M, Smith E, Fonarow G, Hernandez A, Pan W, Schwamm L. Off-Hour Admission and In-Hospital Stroke Case Fatality in the Get With The Guidelines-Stroke Program. Stroke 2008, 40: 569-576. PMID: 18988914, DOI: 10.1161/strokeaha.108.519355.Peer-Reviewed Original ResearchConceptsHemorrhagic stroke admissionsOff-hour presentationIschemic stroke admissionsQuality of careHospital case fatalityStroke admissionsHospital mortalityHours presentationCase fatalityIschemic strokeHospital case fatality rateGuidelines-Stroke programGWTG-Stroke programHospital-based outcomesAcute ischemic strokeHospital-level factorsStroke case fatalityTime of presentationCase fatality rateEquation logistic regressionQuality improvement effortsStroke ProgramAcute strokeHemorrhagic strokeHours admission
2006
The Paul Coverdell National Acute Stroke Registry Initial Results from Four Prototypes
Reeves M, Broderick J, Frankel M, LaBresh K, Schwamm L, Moomaw C, Weiss P, Katzan I, Arora S, Heinrich J, Hickenbottom S, Karp H, Malarcher A, Mensah G, Reeves M. The Paul Coverdell National Acute Stroke Registry Initial Results from Four Prototypes. American Journal Of Preventive Medicine 2006, 31: s202-s209. PMID: 17178304, DOI: 10.1016/j.amepre.2006.08.007.Peer-Reviewed Original ResearchConceptsRecombinant tissue plasminogen activatorTissue plasminogen activatorStroke admissionsPaul Coverdell National Acute Stroke RegistryNational Acute Stroke RegistryPlasminogen activatorAcute stroke admissionsAcute Stroke RegistrySmoking cessation counselingPercent of patientsTransient ischemic attackAcute stroke careAcute stroke patientsPercent of admissionsHours of onsetIschemic stroke admissionsHealthcare system levelQuality improvement interventionsYears of ageAntithrombotic treatmentIschemic attackLipid testingStroke RegistryEligible subjectsIschemic stroke
2005
Acute Stroke Care in the US
Reeves M, Arora S, Broderick J, Frankel M, Heinrich J, Hickenbottom S, Karp H, LaBresh K, Malarcher A, Mensah G, Moomaw C, Schwamm L, Weiss P. Acute Stroke Care in the US. Stroke 2005, 36: 1232-1240. PMID: 15890989, DOI: 10.1161/01.str.0000165902.18021.5b.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBrain IschemiaCerebral HemorrhageFemaleFibrinolytic AgentsGeorgiaHospital RecordsHumansInfusions, IntravenousIschemic Attack, TransientMaleMassachusettsMichiganMiddle AgedOhioPilot ProjectsProspective StudiesQuality ControlRecombinant ProteinsRegistriesRetrospective StudiesStrokeThrombolytic TherapyTime FactorsTissue Plasminogen ActivatorTreatment OutcomeUnited StatesConceptsRecombinant tissue plasminogen activatorAcute stroke careStroke careStroke admissionsPaul Coverdell National Acute Stroke RegistryIntravenous recombinant tissue plasminogen activatorNational Acute Stroke RegistryHealth care system levelsAcute stroke admissionsAcute Stroke RegistryTransient ischemic attackAcute stroke patientsHours of onsetIschemic stroke admissionsMinutes of arrivalSecondary prevention practicesAge 60 yearsQuality improvement interventionsTissue plasminogen activatorIschemic attackCessation counselingStroke RegistryIschemic strokeIntracerebral hemorrhageStroke patients