2021
Cognitive Demands Influence Upper Extremity Motor Performance During Recovery From Acute Stroke
Lin D, Erler K, Snider S, Bonkhoff A, DiCarlo J, Lam N, Ranford J, Parlman K, Cohen A, Freeburn J, Finklestein S, Schwamm L, Hochberg L, Cramer S. Cognitive Demands Influence Upper Extremity Motor Performance During Recovery From Acute Stroke. Neurology 2021, 96: e2576-e2586. PMID: 33858997, PMCID: PMC8205451, DOI: 10.1212/wnl.0000000000011992.Peer-Reviewed Original ResearchConceptsIpsilesional upper extremityAcute strokeUpper extremity motor performanceGrip strength performanceUpper extremityCognitive dysfunctionMotor performanceMotor tasksAcute ischemic strokeVoxel-based lesion-symptom mappingGrip strength scoresDorsal anterior insulaBlock performanceBallistic motor taskLesion-symptom mappingIschemic strokeGrip strengthNeuroanatomic sitesCognitive impairmentSensorimotor regionsSymptom mappingStrokeCognitive functionAnterior insulaInjury
2019
Corticospinal Tract Injury Estimated From Acute Stroke Imaging Predicts Upper Extremity Motor Recovery After Stroke
Lin D, Cloutier A, Erler K, Cassidy J, Snider S, Ranford J, Parlman K, Giatsidis F, Burke J, Schwamm L, Finklestein S, Hochberg L, Cramer S. Corticospinal Tract Injury Estimated From Acute Stroke Imaging Predicts Upper Extremity Motor Recovery After Stroke. Stroke 2019, 50: 3569-3577. PMID: 31648631, PMCID: PMC6878199, DOI: 10.1161/strokeaha.119.025898.Peer-Reviewed Original ResearchConceptsUpper extremity motor recoveryAcute stroke hospitalizationCST injuryMotor recoveryCorticospinal tractStroke hospitalizationsPremotor cortexPrimary motorUpper extremity Fugl-MeyerAcute Stroke ImagingAcute stroke workupUpper extremity weaknessUpper extremity recoveryCorticospinal tract injuryExtent of injuryStroke standardsExtremity weaknessStroke workupTract injuryIschemic strokeFugl-MeyerInitial impairmentPredictive valueInjuryStroke imaging
1998
Increased plasma levels of lipid hydroperoxides in patients with ischemic stroke
Polidori M, Frei B, Cherubini A, Nelles G, Rordorf G, Keaney J, Schwamm L, Mecocci P, Koroshetz W, Beal M. Increased plasma levels of lipid hydroperoxides in patients with ischemic stroke. Free Radical Biology And Medicine 1998, 25: 561-567. PMID: 9741593, DOI: 10.1016/s0891-5849(98)00085-9.Peer-Reviewed Original ResearchConceptsIschemic brain injuryCerebral syndromeCortical strokePlasma levelsBrain injuryOxidative stressGlasgow Coma ScaleNIH Stroke ScaleLipid hydroperoxidesStroke ScaleIschemic strokeComa ScaleLacunar infarctsStroke volumeMRI scansPatientsTherapeutic interventionsDay 5Significant negative correlationSignificant positive correlationSyndromeStrokeAscorbic acid concentrationInjuryPositive correlation