2024
Contemporary Prestroke Dual Antiplatelet Use and Symptomatic Intracerebral Hemorrhage Risk After Thrombolysis
Peng T, Schwamm L, Fonarow G, Hassan A, Hill M, Messé S, Coronado F, Falcone G, Sharma R. Contemporary Prestroke Dual Antiplatelet Use and Symptomatic Intracerebral Hemorrhage Risk After Thrombolysis. JAMA Neurology 2024, 81: 722-731. PMID: 38767894, PMCID: PMC11106713, DOI: 10.1001/jamaneurol.2024.1312.Peer-Reviewed Original ResearchRisk of symptomatic intracerebral hemorrhageSymptomatic intracerebral hemorrhageTreated with IV-tPAAcute ischemic strokeIV-tPAAmerican Heart Association and American Stroke AssociationAssociated with lower oddsIschemic strokeDual antiplatelet therapyAssociated with increased riskPropensity score subclassificationAmerican Stroke AssociationIntracerebral hemorrhage riskGWTG-StrokeSymptomatic intracerebral hemorrhage riskGuidelines-StrokeDischarge modified Rankin Scale scoreIn-hospital deathStroke AssociationLower oddsRate of symptomatic intracerebral hemorrhageAntiplatelet therapyCohort studyAssociated with symptomatic intracerebral hemorrhagePrestroke
2020
Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States.
Prabhakaran S, Messé S, Kleindorfer D, Smith E, Fonarow G, Xu H, Zhao X, Lytle B, Cigarroa J, Schwamm L. Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States. Neurology Clinical Practice 2020, 10: 396-405. PMID: 33299667, PMCID: PMC7717635, DOI: 10.1212/cpj.0000000000000736.Peer-Reviewed Original ResearchCryptogenic strokeIschemic strokeStroke etiologyDischarge outcomesHospital treatmentHospital characteristicsMultivariable logistic regressionGWTG-StrokeStroke RegistryNationwide registryMultivariable analysisPatientsLower mortalityHigh mortalityNationwide dataLogistic regressionSubtypesStrokeNational InstituteScale scaleOutcomesTreatmentRegistryHospitalEtiology
2018
Participation in Get With the Guidelines–Stroke and Its Association With Quality of Care for Stroke
Howard G, Schwamm LH, Donnelly JP, Howard VJ, Jasne A, Smith EE, Rhodes JD, Kissela BM, Fonarow GC, Kleindorfer DO, Albright KC. Participation in Get With the Guidelines–Stroke and Its Association With Quality of Care for Stroke. JAMA Neurology 2018, 75: 1331-1337. PMID: 30083763, PMCID: PMC6248106, DOI: 10.1001/jamaneurol.2018.2101.Peer-Reviewed Original ResearchConceptsTissue plasminogen activatorIschemic strokeQuality of careGuidelines-StrokeGWTG-StrokeMean ageNonparticipating hospitalsCare measuresRisk factorsPopulation-based cohort studyPlasminogen activatorLipid profile assessmentParticipants 45 yearsStroke risk factorsQuality Improvement ProgramEvidence-based interventionsExercise counselingNeurologist evaluationAntithrombotic therapyCohort studyAntithrombotic useStroke careMAIN OUTCOMELipid evaluationHospital
2017
Impact of an Expanded Hospital Recognition Program for Stroke Quality of Care
Heidenreich P, Zhao X, Hernandez A, Schwamm L, Smith E, Reeves M, Peterson E, Fonarow G. Impact of an Expanded Hospital Recognition Program for Stroke Quality of Care. Journal Of The American Heart Association 2017, 6: e004278. PMID: 28110310, PMCID: PMC5523627, DOI: 10.1161/jaha.116.004278.Peer-Reviewed Original Research
2016
Association of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke
Song S, Fonarow G, Olson D, Liang L, Schulte P, Hernandez A, Peterson E, Reeves M, Smith E, Schwamm L, Saver J. Association of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke. Stroke 2016, 47: 1294-1302. PMID: 27079809, PMCID: PMC4975426, DOI: 10.1161/strokeaha.115.011874.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke admissionsGWTG-Stroke programIschemic stroke admissionsClinical outcomesStroke admissionsMedicare beneficiariesAcute care US hospitalsHospital-based quality improvement programsGWTG-Stroke hospitalsImproved functional outcomesAmerican Heart AssociationQuality Improvement ProgramGWTG-StrokePostdischarge mortalityAcute strokeIschemic strokeFunctional outcomeHeart AssociationNonparticipating hospitalsStroke hospitalsHospital participationUS hospitalsHospitalPre periodSimilar hospitals
2012
Trends in Smoking Cessation Counseling: Experience From American Heart Association‐Get With The Guidelines
Huang P, Kim C, Lerman A, Cannon C, Dai D, Laskey W, Peacock W, Hernandez A, Peterson E, Smith E, Fonarow G, Schwamm L, Bhatt D. Trends in Smoking Cessation Counseling: Experience From American Heart Association‐Get With The Guidelines. Clinical Cardiology 2012, 35: 396-403. PMID: 22753250, PMCID: PMC6652349, DOI: 10.1002/clc.22023.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmerican Heart AssociationCardiovascular DiseasesChi-Square DistributionCounselingFemaleGuideline AdherenceHumansMaleMiddle AgedMultivariate AnalysisPractice Guidelines as TopicQuality ImprovementRisk AssessmentRisk FactorsRisk Reduction BehaviorSmokingSmoking CessationSmoking PreventionTime FactorsUnited StatesConceptsAmerican Heart AssociationGWTG-CADGWTG-StrokeHeart AssociationSystematic quality improvement programmeCoronary artery disease patientsNational guideline recommendationsSuccessful smoking cessationQuality Improvement ProgramCessation counselingSmoking contributesStroke admissionsGuideline recommendationsRecent smokersSignificant morbidityStroke careStroke patientsSmoking cessationDisease patientsCardiovascular carePatientsAdmissionStudy periodStrokeCareData quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit
Xian Y, Fonarow G, Reeves M, Webb L, Blevins J, Demyanenko V, Zhao X, Olson D, Hernandez A, Peterson E, Schwamm L, Smith E. Data quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit. American Heart Journal 2012, 163: 392-398.e1. PMID: 22424009, DOI: 10.1016/j.ahj.2011.12.012.Peer-Reviewed Original ResearchConceptsMedical recordsDeep venous thrombosis prophylaxisPrimary stroke center certificationGWTG-Stroke hospitalsHospital academic statusStroke center certificationVenous thrombosis prophylaxisNational Stroke RegistryAmerican Heart AssociationQuality Improvement ProgramIntraclass correlationIschemic stroke volumeGuidelines-StrokeGWTG-StrokeStroke RegistryThrombosis prophylaxisNeedle timeSerum creatinineSymptom onsetHeart AssociationCenter certificationStroke volumeRegistry dataRegistry participationCategorical variables
2011
Representativeness of the Get With The Guidelines–Stroke Registry
Reeves M, Fonarow G, Smith E, Pan W, Olson D, Hernandez A, Peterson E, Schwamm L. Representativeness of the Get With The Guidelines–Stroke Registry. Stroke 2011, 43: 44-49. PMID: 21980197, DOI: 10.1161/strokeaha.111.626978.Peer-Reviewed Original ResearchConceptsIschemic stroke admissionsGWTG-Stroke hospitalsGWTG-StrokeMedicare cohortStroke admissionsStroke hospitalsIschemic strokePatient characteristicsMedicare patientsGuidelines-Stroke registryGWTG-Stroke programIschemic stroke populationService Medicare patientsAcute ischemic strokeLength of stayHospital mortalityDischarge homeHospital outcomesAcute strokeStroke populationHospital characteristicsMedicare beneficiariesAdmissionHospitalNational feeImprovement in use of anticoagulation therapy in patients with ischemic stroke: Results from Get With The Guidelines–Stroke
Lewis W, Fonarow G, Grau-Sepulveda M, Smith E, Bhatt D, Hernandez A, Olson D, Peterson E, Schwamm L. Improvement in use of anticoagulation therapy in patients with ischemic stroke: Results from Get With The Guidelines–Stroke. American Heart Journal 2011, 162: 692-699.e2. PMID: 21982662, DOI: 10.1016/j.ahj.2011.07.019.Peer-Reviewed Original ResearchConceptsTransient ischemic attackUse of anticoagulationAtrial fibrillationAnticoagulation therapyGWTG-StrokeEligible patientsStroke patientsIschemic stroke/transient ischemic attackJoint Commission Primary Stroke CentersStroke/transient ischemic attackEligible AF patientsGuidelines-Stroke programIschemic stroke patientsPrimary stroke centerHospital-level characteristicsAnticoagulation useGuidelines-StrokeIschemic attackThromboembolic eventsHospital dischargeIschemic strokeOlder patientsStroke centersAF patientsHispanic patients
2010
Rapid Change in Prescribing Behavior in Hospitals Participating in Get With The Guidelines–Stroke After Release of the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) Clinical Trial Results
Menon B, Frankel M, Liang L, LaBresh K, Ellrodt G, Hernandez A, Fonarow G, Schwamm L, Smith E. Rapid Change in Prescribing Behavior in Hospitals Participating in Get With The Guidelines–Stroke After Release of the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) Clinical Trial Results. Stroke 2010, 41: 2094-2097. PMID: 20634476, DOI: 10.1161/strokeaha.110.584151.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic attackIschemic strokeHigh-risk patients trialAmerican Heart Association Guidelines UpdateManagement of AtherothrombosisPatient clinical trialsGuidelines-StrokeGWTG-StrokeAntithrombotic medicationAntithrombotic therapyStroke ProgramDischarge prescriptionsGuideline updateRandomized trialsConsensus guidelinesHospital characteristicsClinical trialsPrescribing behaviorSustained decreasePatient trialsSustained reductionClinical informationPatientsMatch StudyQuality of Care and Outcomes in Patients With Diabetes Hospitalized With Ischemic Stroke
Reeves M, Vaidya R, Fonarow G, Liang L, Smith E, Matulonis R, Olson D, Schwamm L. Quality of Care and Outcomes in Patients With Diabetes Hospitalized With Ischemic Stroke. Stroke 2010, 41: e409-e417. PMID: 20224058, DOI: 10.1161/strokeaha.109.572693.Peer-Reviewed Original ResearchConceptsQuality of careStroke-related outcomesIschemic stroke patientsStroke patientsRt-PACholesterol treatmentIntravenous recombinant tissue plasminogen activatorRecombinant tissue plasminogen activatorCommon comorbid diseasesGuidelines-Stroke programPercent of patientsSecondary prevention treatmentHours of onsetMultivariable logistic regressionTissue plasminogen activatorUnited States hospitalsQuality improvement effortsGWTG-StrokeHospital mortalityDischarge homeHospital deathHospital outcomesStroke recurrenceComorbid diseasesIschemic strokeCharacteristics, Performance Measures, and In-Hospital Outcomes of the First One Million Stroke and Transient Ischemic Attack Admissions in Get With The Guidelines-Stroke
Fonarow G, Reeves M, Smith E, Saver J, Zhao X, Olson D, Hernandez A, Peterson E, Schwamm L. Characteristics, Performance Measures, and In-Hospital Outcomes of the First One Million Stroke and Transient Ischemic Attack Admissions in Get With The Guidelines-Stroke. Circulation Cardiovascular Quality And Outcomes 2010, 3: 291-302. PMID: 20177051, DOI: 10.1161/circoutcomes.109.921858.Peer-Reviewed Original ResearchConceptsHospital mortality rateIntracerebral hemorrhageQuality of careIschemic strokeSubarachnoid hemorrhageMortality rateTransient ischemic attack admissionsTransient ischemic attack patientsIn-Hospital OutcomesAcute ischemic strokeIschemic stroke patientsAdjusted odds ratioLength of stayQuality improvement effortsGuidelines-StrokeGWTG-StrokeTIA admissionsTIA careTIA patientsHospital outcomesAcute strokeStroke patientsMean ageAttack patientsNational surveillance