2017
Clinical Imaging Factors Associated With Infarct Progression in Patients With Ischemic Stroke During Transfer for Mechanical Thrombectomy
Boulouis G, Lauer A, Siddiqui A, Charidimou A, Regenhardt R, Viswanathan A, Rost N, Leslie-Mazwi T, Schwamm L. Clinical Imaging Factors Associated With Infarct Progression in Patients With Ischemic Stroke During Transfer for Mechanical Thrombectomy. JAMA Neurology 2017, 74: 1361-1367. PMID: 28973081, PMCID: PMC5710581, DOI: 10.1001/jamaneurol.2017.2149.Peer-Reviewed Original ResearchConceptsThrombectomy-capable stroke centersCollateral blood flowIschemic strokeInfarct progressionMechanical thrombectomyCT angiographyMAIN OUTCOMEVessel statusBlood flowImaging factorsHigher adjusted odds ratioVascular imagingFavorable imaging profileHealth Stroke ScoreAcute ischemic strokeHigher National InstitutesAdjusted odds ratioRegional stroke networkStroke care networksStroke centersStroke ScoreConsecutive patientsStroke NetworkClinical severityFutile transfers
2009
False Positive CT Angiography in Brain Death
Greer DM, Strozyk D, Schwamm LH. False Positive CT Angiography in Brain Death. Neurocritical Care 2009, 11: 272-275. PMID: 19390993, DOI: 10.1007/s12028-009-9220-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain DeathBrain EdemaCerebral AngiographyCerebrovascular CirculationCircle of WillisDiagnosis, DifferentialElectroencephalographyFalse Positive ReactionsFemaleHeart ArrestHumansTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedUltrasonography, Doppler, TranscranialConceptsCerebral circulatory arrestBrain criteriaCirculatory arrestBrain deathPositive CT angiographyCerebral blood flowSingle photon emissionTranscranial DopplerNewer testsClinical examinationTomographic angiographyConventional angiographyCT angiographyBlood flowAncillary testsEase of performanceAngiographyDetermination of deathGold standardConfirmatory testDeathPhoton emissionAcceptable testArrestPatients
2001
Heterogeneous spatial-temporal evolution of DWI/PWI in human cerebral ischemia
Wu O, Schwamm L, Koroshetz W, Gonzalez R, Pan V, Benner T, Copen W, Ostergaard L, Sorensen A. Heterogeneous spatial-temporal evolution of DWI/PWI in human cerebral ischemia. Stroke 2001, 32: 348-348. DOI: 10.1161/str.32.suppl_1.348-d.Peer-Reviewed Original ResearchCerebral blood flowHuman cerebral ischemiaDWI/PWICerebral blood volumeMean transit timeApparent diffusion coefficientFractional anisotropyCerebral ischemiaRim tissueHuman ischemic strokeElevated fractional anisotropyTwo-sample t-testDWI abnormalitiesInitial DWIIschemic strokeMCA territoryAcute stageIschemic coreSalvageable tissueIntralesional heterogeneityIschemic tissueBlood flowBlood volumeRisk tissuePatients
1999
Hyperacute Stroke: Simultaneous Measurement of Relative Cerebral Blood Volume, Relative Cerebral Blood Flow, and Mean Tissue Transit Time
Sorensen A, Copen W, Ostergaard L, Buonanno F, Gonzalez R, Rordorf G, Rosen B, Schwamm L, Weisskoff R, Koroshetz W. Hyperacute Stroke: Simultaneous Measurement of Relative Cerebral Blood Volume, Relative Cerebral Blood Flow, and Mean Tissue Transit Time. Radiology 1999, 210: 519-27. PMID: 10207439, DOI: 10.1148/radiology.210.2.r99fe06519.Peer-Reviewed Original ResearchConceptsRelative cerebral blood flowCerebral blood flowRelative cerebral blood volumeCerebral blood volumeBlood flowBlood volumeTissue transit timeLesion volumeMR imagingDiffusion findingsAcute lesion volumesCompensatory hemodynamic responseHemodynamic MR imagingCerebral ischemic strokeOnset of symptomsInitial blood flowAltered blood flowBlood volume mapsFunctional magnetic resonance imagingMagnetic resonance imagingTransit time mapsBlood flow mapsInitial blood volumeInfarct volumeHemodynamic abnormalities