2014
Intravenous Fibrinolysis Eligibility: A Survey of Stroke Clinicians' Practice Patterns and Review of the Literature
De Los Rios F, Kleindorfer D, Guzik A, Ortega-Gutierrez S, Sangha N, Kumar G, Grotta J, Lee J, Meyer B, Schwamm L, Khatri P, Investigators S. Intravenous Fibrinolysis Eligibility: A Survey of Stroke Clinicians' Practice Patterns and Review of the Literature. Journal Of Stroke And Cerebrovascular Diseases 2014, 23: 2130-2138. PMID: 25113084, PMCID: PMC4157964, DOI: 10.1016/j.jstrokecerebrovasdis.2014.03.024.Peer-Reviewed Original ResearchConceptsStroke cliniciansPractice patternsEligible patientsSymptom onsetEuropean Cooperative Acute Stroke Study-III criteriaIntravenous recombinant tissue plasminogen activator useCurrent American Heart Association guidelinesRecombinant tissue plasminogen activator useTissue plasminogen activator useAmerican Heart Association guidelinesHealth Stroke ScaleHeart Association guidelinesHour time frameClinician practice patternsNational InstituteSevere strokeStroke ScaleIschemic strokeMild strokeAssociation guidelinesMost cliniciansElderly individualsEligibility criteriaDrug AdministrationInvestigator meeting
2009
Unsuspected coagulopathy rarely prevents IV thrombolysis in acute ischemic strokeSYMBOL
Rost N, Masrur S, Pervez M, Viswanathan A, Schwamm L. Unsuspected coagulopathy rarely prevents IV thrombolysis in acute ischemic strokeSYMBOL. Neurology 2009, 73: 1957-1962. PMID: 19940272, PMCID: PMC4109188, DOI: 10.1212/wnl.0b013e3181c5b46d.Peer-Reviewed Original ResearchConceptsTissue plasminogen activatorEmergency departmentAbsolute contraindicationStroke patientsAmerican Heart Association/American Stroke Association guidelinesAcute ischemic stroke patientsAmerican Stroke Association guidelinesGuidelines-Stroke databaseIschemic stroke patientsCurrent practice guidelinesReferral centerRelative contraindicationThrombolysis patientsEarly administrationRetrospective reviewStroke databaseThrombolytic therapyTreatable factorsDiagnostic neuroimagingAssociation guidelinesClinical evaluationPractice guidelinesBleeding diathesisCoagulopathyPatients