2017
AMP-activated protein kinase and adenosine are both metabolic modulators that regulate chloride secretion in the shark rectal gland (Squalus acanthias)
Neuman RI, van Kalmthout JAM, Pfau DJ, Menendez DM, Young LH, Forrest JN. AMP-activated protein kinase and adenosine are both metabolic modulators that regulate chloride secretion in the shark rectal gland (Squalus acanthias). American Journal Of Physiology - Cell Physiology 2017, 314: c473-c482. PMID: 29351415, PMCID: PMC5966785, DOI: 10.1152/ajpcell.00171.2017.Peer-Reviewed Original ResearchAdenosineAminoimidazole CarboxamideAMP-Activated Protein KinasesAnimalsCell HypoxiaChloridesCystic Fibrosis Transmembrane Conductance RegulatorEnergy MetabolismEnzyme ActivationEnzyme ActivatorsFish ProteinsPerfusionPhosphorylationProtein SubunitsRibonucleotidesSalt GlandSecretory PathwaySqualus acanthiasTissue Culture Techniques
2009
AMP‐activated protein kinase: a core signalling pathway in the heart
Kim AS, Miller EJ, Young LH. AMP‐activated protein kinase: a core signalling pathway in the heart. Acta Physiologica 2009, 196: 37-53. PMID: 19239414, DOI: 10.1111/j.1748-1716.2009.01978.x.BooksConceptsProtein kinaseEssential cellular processesTumor suppressor LKB1Downstream AMPK targetsProduction of ATPProtein phosphataseAMPK targetsActivated AMPKIntracellular glycogen accumulationCellular processesUpstream kinaseFatty acid metabolismCardiac myocyte hypertrophyAMPK activationAMPK activityImportant intracellularMolecular mechanismsMajor regulatorAMPKProtein synthesisKinaseAcid metabolismOral hypoglycaemic drugsGlycogen accumulationType 2 diabetes