2017
Disruption of Brain–Heart Coupling in Sepsis
Admiraal MM, Gilmore EJ, Van Putten MJAM, Zaveri HP, Hirsch LJ, Gaspard N. Disruption of Brain–Heart Coupling in Sepsis. Journal Of Clinical Neurophysiology 2017, 34: 413-420. PMID: 28520632, DOI: 10.1097/wnp.0000000000000381.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlpha RhythmBrain DiseasesBrain StemComaElectrocardiographyFemaleHeart RateHumansMaleMiddle AgedNeurovascular CouplingSepsisSeverity of Illness IndexThalamus
2012
Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II)
Bauerschmidt A, Koshkelashvili N, Ezeani CC, Yoo JY, Zhang Y, Manganas LN, Kapadia K, Palenzuela D, Schmidt C, Lief R, Kiely BT, Choezom T, McClurkin M, Shorten A, Detyniecki K, Hirsch LJ, Giacino JT, Blumenfeld H. Prospective assessment of ictal behavior using the revised Responsiveness in Epilepsy Scale (RES-II). Epilepsy & Behavior 2012, 26: 25-28. PMID: 23201609, PMCID: PMC3741052, DOI: 10.1016/j.yebeh.2012.10.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultBehaviorCohort StudiesConsciousness DisordersElectroencephalographyEpilepsyFemaleHumansMaleProspective StudiesSeverity of Illness IndexVideo Recording
2010
Intracortical EEG for the Detection of Vasospasm in Patients with Poor-Grade Subarachnoid Hemorrhage
Stuart RM, Waziri A, Weintraub D, Schmidt MJ, Fernandez L, Helbok R, Kurtz P, Lee K, Badjatia N, Emerson R, Mayer SA, Connolly ES, Hirsch LJ, Claassen J. Intracortical EEG for the Detection of Vasospasm in Patients with Poor-Grade Subarachnoid Hemorrhage. Neurocritical Care 2010, 13: 355-358. PMID: 20652443, DOI: 10.1007/s12028-010-9414-6.Peer-Reviewed Original ResearchConceptsPoor-grade SAH patientsAlpha/delta ratioDetection of vasospasmSAH patientsPoor-grade subarachnoid hemorrhageIntracortical electroencephalographyQuantitative EEG parametersQuantitative EEG analysisAngiographic confirmationAngiographic vasospasmSubarachnoid hemorrhageSustained decreaseVasospasmPatientsBaseline EEGPercent changeDepth electrodesQEEG recordingsLarger studySurface EEGDelta ratioIntracortical EEGEEG parametersAlarm criteriaBaselineIntracranial Multimodal Monitoring for Acute Brain Injury: A Single Institution Review of Current Practices
Stuart RM, Schmidt M, Kurtz P, Waziri A, Helbok R, Mayer SA, Lee K, Badjatia N, Hirsch LJ, Connolly ES, Claassen J. Intracranial Multimodal Monitoring for Acute Brain Injury: A Single Institution Review of Current Practices. Neurocritical Care 2010, 12: 188-198. PMID: 20107926, DOI: 10.1007/s12028-010-9330-9.Peer-Reviewed Original ResearchConceptsAcute brain injuryBrain injurySevere acute brain injuryNeurological intensive care unitInsertion techniqueSecondary brain injuryDay of admissionMethodsSixty-one patientsRate of hematomaSingle-institution reviewIntensive care unitBrain tissue oxygenCerebral blood flowFocal brain injuryMultimodality brain monitoringPatient-specific selectionInvasive monitoring devicesHospital lengthFrequent complicationNICU lengthPatient demographicsCare unitMultimodality monitoringConsecutive seriesInstitution review
2007
A Randomized, Double‐Blind, Placebo‐Controlled Trial of Donepezil to Improve Memory in Epilepsy
Hamberger MJ, Palmese CA, Scarmeas N, Weintraub D, Choi H, Hirsch LJ. A Randomized, Double‐Blind, Placebo‐Controlled Trial of Donepezil to Improve Memory in Epilepsy. Epilepsia 2007, 48: 1283-1291. PMID: 17484756, DOI: 10.1111/j.1528-1167.2007.01114.x.Peer-Reviewed Original ResearchMeSH KeywordsCholinesterase InhibitorsCognition DisordersCross-Over StudiesDonepezilDose-Response Relationship, DrugDouble-Blind MethodEpilepsyHealth StatusHumansIndansMemory DisordersNeuropsychological TestsPiperidinesPlacebosQuality of LifeSeverity of Illness IndexSocial AdjustmentTreatment OutcomeConceptsSubjective memory difficultyMemory difficultiesPsychological functionsCognitive functionSocial functioningSelf-rated memoryAssessment of memorySubjective memory complaintsTrial of donepezilDonepezil treatmentSubjective memoryMemory complaintsSelf-rated qualityMemoryTreatment phaseEpilepsy patientsMoodFunctioningParticular epilepsy syndromesGroup resultsDonepezilAcetylcholinesterase inhibitorsDifficultiesPlacebo treatmentSeizure frequency