2018
Presurgical language fMRI: Technical practices in epilepsy surgical planning
Benjamin CFA, Dhingra I, Li AX, Blumenfeld H, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen RA, Warfield SK, Peters JM, Reutens D, Połczyńska MM, Hirsch LJ, Spencer DD. Presurgical language fMRI: Technical practices in epilepsy surgical planning. Human Brain Mapping 2018, 39: 4032-4042. PMID: 29962111, PMCID: PMC6175127, DOI: 10.1002/hbm.24229.Peer-Reviewed Original ResearchConceptsLanguage functional MRIFunctional MRISurgical planningEpilepsy surgical planningEpilepsy surgical programsGeneral linear modelingBlood flowClinical practicePatient careSurgical programsRoutine useMarked heterogeneityClinical applicationVerbal fluencyData highlightFMRI dataMost programsPatientsWidespread useEpilepsyIndividualsMRICarePresurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning
Benjamin CFA, Li AX, Blumenfeld H, Constable RT, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen R, Warfield SK, Peters JM, Reutens D, Połczyńska M, Spencer DD, Hirsch LJ. Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning. Human Brain Mapping 2018, 39: 2777-2785. PMID: 29528160, PMCID: PMC6033659, DOI: 10.1002/hbm.24039.Peer-Reviewed Original ResearchMeSH KeywordsBrain MappingEpilepsyHumansLanguageMagnetic Resonance ImagingNeurosurgical ProceduresOutcome Assessment, Health CarePreoperative CareConceptsLanguage functional MRISurgical marginsFunctional MRIPatient outcomesClinical practiceEpilepsy surgical planningEpilepsy surgical programsCurrent clinical practiceDirect brain stimulationEpilepsy surgeryStimulation mappingBrain stimulationClinical teamLanguage lateralizationSurgical programsSurgical planningLanguage-critical areasFMRI findingsFMRI paradigmUnexpected preservationFurther validationLanguage declineAdultsOutcomesChildren
2015
Quantitative EEG Is an Objective, Sensitive, and Reliable Indicator of Transient Anesthetic Effects During Wada Tests
Tu B, Assassi NJ, Bazil CW, Hamberger MJ, Hirsch LJ. Quantitative EEG Is an Objective, Sensitive, and Reliable Indicator of Transient Anesthetic Effects During Wada Tests. Journal Of Clinical Neurophysiology 2015, 32: 152-158. PMID: 25580802, PMCID: PMC4385440, DOI: 10.1097/wnp.0000000000000154.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnestheticsBrainElectroencephalographyEpilepsyFemaleHumansMaleMiddle AgedPreoperative CareSensitivity and SpecificityYoung AdultConceptsPower ratio
2002
Levetiracetam May Be More Effective for Late-Onset Partial Epilepsy
Bazil CW, Rose A, Resor S, Yapicular B, Hirsch LJ. Levetiracetam May Be More Effective for Late-Onset Partial Epilepsy. JAMA Neurology 2002, 59: 1905-1908. PMID: 12470178, DOI: 10.1001/archneur.59.12.1905.Peer-Reviewed Original ResearchConceptsLevetiracetam therapySeizure typesRetrospective medical record reviewFrontal lobe onsetSame seizure typesTemporal lobe onsetLarge prospective trialsMedical record reviewSubset of patientsPopulation of patientsLocalization-related epilepsyNew antiepileptic drugsProspective trialRefractory epilepsyRecord reviewAntiepileptic drugsPartial epilepsySignificant worseningDrug choiceClinical experiencePatientsEpileptic seizuresEpilepsyCertain drugsCertain subpopulations