2013
7T MR spectroscopic imaging in the localization of surgical epilepsy
Pan JW, Duckrow RB, Gerrard J, Ong C, Hirsch LJ, Resor SR, Zhang Y, Petroff O, Spencer S, Hetherington HP, Spencer DD. 7T MR spectroscopic imaging in the localization of surgical epilepsy. Epilepsia 2013, 54: 1668-1678. PMID: 23895497, PMCID: PMC3938332, DOI: 10.1111/epi.12322.Peer-Reviewed Original ResearchConceptsSevere metabolic abnormalitiesLocalization-related epilepsyMR spectroscopic imagingN-acetyl aspartateComplete resectionMetabolic abnormalitiesBetter outcomesMedial temporal lobe epilepsyResection regionTemporal lobe epilepsyNAA/CrSeizure onset zoneSurgical resectionLobe epilepsySurgical approachSeizure localizationMetabolic dysfunctionInternational LeagueSurgical epilepsyGray matterEpilepsyResectionAbnormalitiesMRSI abnormalitiesOutcome prediction
2009
Seizures in Patients Undergoing Resection of Low‐Grade Gliomas
Hirsch LJ. Seizures in Patients Undergoing Resection of Low‐Grade Gliomas. Epilepsy Currents 2009, 9: 98-100. PMID: 19693324, PMCID: PMC2728484, DOI: 10.1111/j.1535-7511.2009.01305.x.Peer-Reviewed Original ResearchLow-grade gliomasPostoperative seizure controlGross total resectionSeizure controlSeizure characteristicsLong seizure historyPatients Undergoing ResectionRetrospective chart reviewCohort of patientsMajority of patientsPoor seizure controlTreatment-related variablesSimple partial seizuresUndergoing resectionInitial surgeryPharmacoresistant seizuresSeizure improvementSeizure recurrenceAdult patientsChart reviewRare seizuresSubtotal resectionSurgical resectionFavorable prognosisPartial seizures