A Randomized, Double‐Blind, Placebo‐Controlled Trial of Donepezil to Improve Memory in Epilepsy
Hamberger MJ, Palmese CA, Scarmeas N, Weintraub D, Choi H, Hirsch LJ. A Randomized, Double‐Blind, Placebo‐Controlled Trial of Donepezil to Improve Memory in Epilepsy. Epilepsia 2007, 48: 1283-1291. PMID: 17484756, DOI: 10.1111/j.1528-1167.2007.01114.x.Peer-Reviewed Original ResearchMeSH KeywordsCholinesterase InhibitorsCognition DisordersCross-Over StudiesDonepezilDose-Response Relationship, DrugDouble-Blind MethodEpilepsyHealth StatusHumansIndansMemory DisordersNeuropsychological TestsPiperidinesPlacebosQuality of LifeSeverity of Illness IndexSocial AdjustmentTreatment OutcomeConceptsSubjective memory difficultyMemory difficultiesPsychological functionsCognitive functionSocial functioningSelf-rated memoryAssessment of memorySubjective memory complaintsTrial of donepezilDonepezil treatmentSubjective memoryMemory complaintsSelf-rated qualityMemoryTreatment phaseEpilepsy patientsMoodFunctioningParticular epilepsy syndromesGroup resultsDonepezilAcetylcholinesterase inhibitorsDifficultiesPlacebo treatmentSeizure frequency