“Tectonic” hippocampal malformations in patients with temporal lobe epilepsy
Sloviter RS, Kudrimoti HS, Laxer KD, Barbaro NM, Chan S, Hirsch LJ, Goodman RR, Pedley TA. “Tectonic” hippocampal malformations in patients with temporal lobe epilepsy. Epilepsy Research 2004, 59: 123-153. PMID: 15246116, DOI: 10.1016/j.eplepsyres.2004.04.001.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyDentate gyrusHippocampal sclerosisFebrile seizuresLobe epilepsyEarly febrile seizuresTypical hippocampal sclerosisNeuronal marker NeuN.Subgroup of patientsAntecedent febrile seizuresTemporal lobe structuresMinor cell lossSubsequent epilepsyNeuronal lossSurgical treatmentHippocampal atrophySynaptic markersHippocampal anomaliesRetrospective analysisEpilepsy patientsHippocampal malformationsPatientsCell lossHippocampusConventional imaging methods