Impact of Steroid Withdrawal on Gene Expression Profiling, Donor Derived Cell-Free DNA, and Clinical Outcomes in the SHORE Registry
Bellumkonda L, Uriel N, Fu Y, Shen L, Qu K, Baran D. Impact of Steroid Withdrawal on Gene Expression Profiling, Donor Derived Cell-Free DNA, and Clinical Outcomes in the SHORE Registry. The Journal Of Heart And Lung Transplantation 2023, 42: s494. DOI: 10.1016/j.healun.2023.02.1362.Peer-Reviewed Original ResearchDe novo donor-specific antibodiesDd-cfDNA levelsCardiac allograft vasculopathySteroid withdrawalGraft dysfunctionCell-free DNAGEP scoreGene expression profilingMulti-organ transplant recipientsNovo donor-specific antibodiesDe novo DSAPost-heart transplantSteroid withdrawal groupDonor-specific antibodiesAllograft vasculopathySteroid doseCause mortalityTransplant recipientsMethods PatientsSteroid treatmentComplete discontinuationPropensity matchingClinical outcomesOutcomes RegistryWithdrawal group