Connexin Hemichannel Composition Determines the FGF-1–induced Membrane Permeability and Free [Ca2+]i Responses
Schalper K, Palacios-Prado N, Retamal M, Shoji K, Martínez A, Sáez J. Connexin Hemichannel Composition Determines the FGF-1–induced Membrane Permeability and Free [Ca2+]i Responses. Molecular Biology Of The Cell 2008, 19: 3501-3513. PMID: 18495870, PMCID: PMC2488314, DOI: 10.1091/mbc.e07-12-1240.Peer-Reviewed Original ResearchConceptsHeLa cellsC-terminusP38 MAP kinase-dependent pathwayMembrane permeabilityMAP kinase-dependent pathwayDifferent connexin typesKinase-dependent pathwayFGF-1HeLa transfectantsDiverse cellsRegulatory sitesCellular responsesCell surfaceCell permeabilizationHemichannelsConnexin typesSerum-free mediumCx26CellsPossible roleCell densityCx43Early intracellularPermeabilizationTransfectants