2023
Costs and Resource Utilization of People with Stable Heart Failure and Insomnia: Evidence from a Randomized Trial of Cognitive Behavioral Therapy for Insomnia
Hollenbeak C, Jeon S, Connell M, Conley S, Yaggi H, Redeker N. Costs and Resource Utilization of People with Stable Heart Failure and Insomnia: Evidence from a Randomized Trial of Cognitive Behavioral Therapy for Insomnia. Behavioral Sleep Medicine 2023, 22: 263-274. PMID: 37530117, PMCID: PMC10834836, DOI: 10.1080/15402002.2023.2241589.Peer-Reviewed Original ResearchSelf-management groupChronic heart failureHeart failureOutpatient visitsStable chronic heart failureCBT-I groupHalf of patientsStable heart failureEmergency department visitsPhysician office visitsSelf-management educationEffects of CBTCognitive behavioral therapyImpact of CBTUsual careDepartment visitsMultivariable analysisOffice visitsInpatient admissionsInpatient hospitalizationClinical trialsInsomnia symptomsHealthcare costsPatientsUnivariate comparisonsSleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia.
Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.Peer-Reviewed Original ResearchConceptsChronic heart failureCognitive behavioral therapyHeart failureGroup time effectsRest-activity rhythmBehavioral therapyChronic insomniaCBT-I groupSelf-reported cognitive functionProportion of participantsTrial of CBTQuality of lifeSelf-management strategiesGroup-based CBTWalk distanceSleep apneaChronic illnessWrist actigraphyCognitive impairmentInsomniaTherapyCognitive functionMinute walkSelf-reported cognitive abilitiesBaseline cognitionEE110 Costs and Resource Utilization of People with Stable Heart Failure and Insomnia: Evidence from a Randomized Trial
Hollenbeak C, Jeon S, O'Connell M, Conley S, Yaggi H, Redeker N. EE110 Costs and Resource Utilization of People with Stable Heart Failure and Insomnia: Evidence from a Randomized Trial. Value In Health 2023, 26: s79-s80. DOI: 10.1016/j.jval.2023.03.414.Peer-Reviewed Original Research0395 Effects of Insomnia and Rest-Activity on Hospitalizations and Emergency Department Visits in People with Stable Heart Failure
Jeon S, Conley S, Hollenbeak C, O’Connell M, Yaggi H, Jacoby D, Wang Z, Tocchi C, Redeker N. 0395 Effects of Insomnia and Rest-Activity on Hospitalizations and Emergency Department Visits in People with Stable Heart Failure. Sleep 2023, 46: a175-a175. DOI: 10.1093/sleep/zsad077.0395.Peer-Reviewed Original ResearchRest-activity rhythmED visitsHeart failureRisk factorsInsomnia Severity IndexHazard ratioEffects of insomniaInsomnia severityNew York Heart Association classDate of hospitalizationClinical risk factorsStable heart failureEmergency department visitsRandomized clinical trialsSelf-management educationAvailable medical recordsProportional hazards modelCognitive behavioral therapyGreater comorbidityHF patientsHigher insomnia severityCardiac eventsEarly hospitalizationFirst hospitalizationFrequent hospitalizations
2021
342 CBT-I Has Sustained Effects on Insomnia Versus Heart-Failure Self-Management Education among Adults with Chronic Heart Failure
Redeker N, Bessette A, Breazeale S, Conley S, Hollenbeak C, Hwang Y, Iannacco J, Jacoby D, Kelly-Hauser J, Linsky S, Moemeka L, Nwanaji-Enwerem U, O’Connell M, Yaggi H, Jeon S. 342 CBT-I Has Sustained Effects on Insomnia Versus Heart-Failure Self-Management Education among Adults with Chronic Heart Failure. Sleep 2021, 44: a136-a137. DOI: 10.1093/sleep/zsab072.341.Peer-Reviewed Original ResearchChronic heart failurePittsburgh Sleep Quality IndexHeart failureSleep apneaSleep disturbance questionnaireHS groupInsomnia severityStable chronic heart failureContinuous positive airway pressureSelf-reported sleep durationCBT-I interventionPoor daytime functionMild sleep apneaPositive airway pressureSleep-related cognitionsSleep Quality IndexModerate-severe insomniaCognitive behavioral therapyAirway pressureDaytime symptomsDaytime functionClinical insomniaSleep ScaleMild insomniaSleep qualityTreatment-Emergent Central Sleep Apnea
Zinchuk A, Yaggi H. Treatment-Emergent Central Sleep Apnea. 2021, 85-102. DOI: 10.1007/978-3-030-57942-5_8.ChaptersTreatment-emergent central sleep apneaContinuous positive airway pressureCentral sleep apneaObstructive sleep apneaSleep apneaPositive airway pressureUpper airway collapsibilityUpper airway patencyMulti-modality therapyVentilatory control systemAirway collapsibilityAirway pressureOpioid useOSA patientsAirway patencyHeart failureAtrial fibrillationCarbonic anhydrase inhibitorsCentral sleepPoor adherenceOptimal treatmentSedative hypnoticsClinical careApneaMultifactorial nature
2020
Obstructive sleep apnoe and cardiovascular, heart failure and mortality outcomes with empagliflozin versus placebo in the EMPA-REG OUTCOME trial
Yaggi H, Eliasson B, Kasai T, Marx N, Zinman B, Inzucchi S, Wanner C, Zwiener I, Wojeck B, Neeland I, Johansen O. Obstructive sleep apnoe and cardiovascular, heart failure and mortality outcomes with empagliflozin versus placebo in the EMPA-REG OUTCOME trial. European Heart Journal 2020, 41: ehaa946.2883. DOI: 10.1093/ehjci/ehaa946.2883.Peer-Reviewed Original ResearchEMPA-REG OUTCOMECardiovascular diseaseIncidence rateMajor adverse CV eventsPlacebo-controlled outcome trialsAdverse CV eventsGlomerular filtration rateSystolic blood pressureCox regression modelStandard of careType 2 diabetesCV deathCV eventsCV outcomesMultivariable adjustmentInhibitor empagliflozinOutcome trialsBlood pressureHeart failureWaist circumferenceMortality outcomesSodium glucoseFiltration rateMetabolic disturbancesPatients
2018
0881 Insomnia Is Related To Self-care In People With Stable Heart Failure
Conley S, Jeon S, Yaggi H, Jacoby D, Hollenbeak C, O’Connell M, Linsky S, Darden J, Gaiser E, Kelly-Hauser J, Matthew B, Richardson P, Redeker N. 0881 Insomnia Is Related To Self-care In People With Stable Heart Failure. Sleep 2018, 41: a327-a328. DOI: 10.1093/sleep/zsy061.880.Peer-Reviewed Original ResearchSelf-care maintenanceInsomnia Severity IndexPittsburgh Sleep Quality IndexStable heart failureHeart failureEpworth Sleepiness ScaleSleep disturbance questionnaireCognitive behavioral therapySleep characteristicsSleep-related cognitionsInsomnia severityStable chronic heart failureBehavioral therapyChronic heart failureSelf-care confidenceHeart Failure IndexUntreated sleep apneaSleep Quality IndexPoor sleep qualitySelf-care managementYears of ageSleep onset latencyHF patientsHigher insomnia severitySleep apnea
2017
Cognitive behavioral therapy for insomnia in stable heart failure: Protocol for a randomized controlled trial
Redeker NS, Knies AK, Hollenbeak C, Yaggi H, Cline J, Andrews L, Jacoby D, Sullivan A, O'Connell M, Iennaco J, Finoia L, Jeon S. Cognitive behavioral therapy for insomnia in stable heart failure: Protocol for a randomized controlled trial. Contemporary Clinical Trials 2017, 55: 16-23. PMID: 28159703, PMCID: PMC5348292, DOI: 10.1016/j.cct.2017.01.009.Peer-Reviewed Original ResearchConceptsEvent-free survivalStable heart failureHealth care utilizationSelf-management educationHeart failureCognitive behavioral therapyCost-effectiveness analysisHF patientsCare utilizationSleep characteristicsMedical record reviewParallel-group RCTFunctional performanceStochastic cost-effectiveness analysisEffects of CBTAttention control conditionIncident mortalityDaytime symptomsRecord reviewComorbid insomniaHF settingDaytime functionGroup RCTChronic insomniaWrist actigraphy
2010
Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack
Bravata DM, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight HJ, Lo A, Richerson GB, Gorman M, Williams LS, Brass LM, Agostini J, Mohsenin V, Roux F, Yaggi HK. Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack. Stroke 2010, 41: 1464-1470. PMID: 20508184, PMCID: PMC4567557, DOI: 10.1161/strokeaha.109.566745.Peer-Reviewed Original ResearchConceptsRecurrent vascular eventsVascular event ratesIntervention patientsSleep apneaTIA patientsVascular eventsContinuous positive airway pressure (CPAP) adherenceAcute transient ischemic attackTransient ischemic attack patientsContinuous positive airway pressurePositive airway pressure adherenceEvent ratesTransient ischemic attackPositive airway pressureCongestive heart failureMajority of patientsSleep apnea patientsIschemic attackRecurrent TIAAirflow obstructionAirway pressureControl patientsCPAP useHeart failureMyocardial infarction