Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells
Ranjan K, Waghela BN, Vaidya FU, Pathak C. Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells. International Journal Of Molecular Sciences 2020, 21: 6890. PMID: 32961826, PMCID: PMC7555701, DOI: 10.3390/ijms21186890.Peer-Reviewed Original ResearchConceptsFADD proteinCancer cellsAnti-apoptotic genesCaveolar pathwayDeath domainCellular pathwaysCancer cell proliferationCytosolic expressionFADD expressionCell deathApoptosis inducersInduces ApoptosisExpression of FasProteinCell proliferationApoptosisNF-κB activationSimultaneous regulationInflammatory signalingExpressionCellsNLRP3 inflammasome primingRegulationPathwayInflammasome priming