2022
Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer
Pathak C, Vaidya F, Waghela B, Chhipa A, Tiwari B, Ranjan K. Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer. 2022, 535-550. DOI: 10.1007/978-981-15-9411-3_44.ChaptersRegulated cell deathCell deathDanger-associated molecular patternsOxidative stressTranscription factorsMolecular mechanismsCancer progressionCellular dysfunctionMolecular patternsRedox imbalanceCancer cellsPathological consequencesTypes of cancerROS generationCurrent understandingAGEs/RAGENucleic acidsAdvanced glycation end productsEnd productsGlycation of proteinsRAGE interactionAccumulationPathophysiological effectsGenesGlycation end products
2020
AGE-RAGE synergy influences programmed cell death signaling to promote cancer
Waghela BN, Vaidya FU, Ranjan K, Chhipa AS, Tiwari BS, Pathak C. AGE-RAGE synergy influences programmed cell death signaling to promote cancer. Molecular And Cellular Biochemistry 2020, 476: 585-598. PMID: 33025314, DOI: 10.1007/s11010-020-03928-y.Peer-Reviewed Original ResearchConceptsCell deathCancer cellsCell death machinerySet of genesCellular redox balanceSignal transduction pathwaysCell death pathwaysComplex signaling mechanismsCell survival mechanismAGE-RAGEDeath machineryCellular reprogrammingTransduction pathwaysDeath pathwaysMolecular paradigmRedox balanceSurvival mechanismSignaling mechanismCancer progressionAGE-RAGE signalingPresent review focusProgression of malignancyTypes of cancerUpregulated expressionChronic hyperglycemic conditions