2023
Human Immunodeficiency Virus Status, Tenofovir Exposure, and the Risk of Poor Coronavirus Disease 19 Outcomes: Real-World Analysis From 6 United States Cohorts Before Vaccine Rollout
Lea A, Leyden W, Sofrygin O, Marafino B, Skarbinski J, Napravnik S, Agil D, Augenbraun M, Benning L, Horberg M, Jefferson C, Marconi V, Park L, Gordon K, Bastarache L, Gangireddy S, Althoff K, Coburn S, Gebo K, Lang R, Williams C, Silverberg M. Human Immunodeficiency Virus Status, Tenofovir Exposure, and the Risk of Poor Coronavirus Disease 19 Outcomes: Real-World Analysis From 6 United States Cohorts Before Vaccine Rollout. Clinical Infectious Diseases 2023, 76: 1727-1734. PMID: 36861341, PMCID: PMC10209434, DOI: 10.1093/cid/ciad084.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAdjusted risk ratioCOVID-19 hospitalizationMechanical ventilationTenofovir useHIV statusAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSevere coronavirus disease 2019 (COVID-19) outcomesSyndrome coronavirus 2 infectionCoronavirus disease 2019 (COVID-19) outcomesHuman immunodeficiency virus statusCohort of PWHCD4 cell countCharlson Comorbidity IndexCoronavirus 2 infectionHIV RNA levelsUnited States cohortBody mass indexCOVID-19 severityCOVID-19 vaccine availabilityReal-world analysisTenofovir exposureComorbidity indexMass index
2012
Patient-Reported Symptoms on the Antiretroviral Regimen Efavirenz/Emtricitabine/Tenofovir
Edelman EJ, Gordon K, Rodriguez-Barradas MC, Justice F. Patient-Reported Symptoms on the Antiretroviral Regimen Efavirenz/Emtricitabine/Tenofovir. AIDS Patient Care And STDs 2012, 26: 312-319. PMID: 22612469, PMCID: PMC3412583, DOI: 10.1089/apc.2012.0044.Peer-Reviewed Original ResearchMeSH KeywordsAdenineAlkynesAnti-HIV AgentsBenzoxazinesCohort StudiesCross-Sectional StudiesCyclopropanesDeoxycytidineDrug Therapy, CombinationEmtricitabineFemaleHealth StatusHIV InfectionsHumansMaleMiddle AgedOrganophosphonatesQuality of LifeSeverity of Illness IndexTenofovirTreatment OutcomeVeteransConceptsEFV/FTC/TDFCombination antiretroviral therapyFTC/TDFHealth-related qualityTDF useSymptom experienceEfavirenz/emtricitabine/tenofovirVeterans Aging Cohort StudyPatient-reported symptomsAging Cohort StudyEmtricitabine/tenofovirCross-sectional analysisAntiretroviral therapyCohort studyMost patientsPatient tolerabilitySymptom burdenTreatment characteristicsPatientsDisease severityAnalytic sampleTenofovirSymptomsTDFAssociation